[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100369718":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":58,"collaborators":60,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":10,"maxAge":10,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Retrospective Chart Review",null,"Medical record chart review of women seen previously for clinical care prior to June 20, 2019 at participating institutions with SCD and hydroxyurea exposure during gestation or lactation will be identified by healthcare providers.",[13],"Other: Chart Review",{"label":15,"type":10,"description":16,"interventionNames":17},"Participant Survey and Retrospective Chart Review","Participants providing their medical records without the assistance of a health care provider will be asked to complete a questionnaire through REDCap and will have the option to upload their deidentified medical records if they are available.",[13,18],"Other: Survey",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Chart Review","Medical records or data available from previous clinical care prior to June 20, 2019 about pregnancy and breastfeeding outcomes, both for babies with hydroxyurea exposure and other babies by these same women.",[15,9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Survey","Women who choose to participate directly and provide information in survey format will receive a brief survey and the option to upload their medical records (if available) into Cincinnati Children's maintained REDCap database.",[15],[29],{"name":30,"affiliation":5,"role":31},"Russell Ware, MD","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Teresa Latham","CONTACT","513-803-7922","Teresa.Latham@cchmc.org",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Cincinnati Children's Hospital Medical Center","RECRUITING","Cincinnati","Ohio","45229","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-84.51439,39.12711,{"lat":51,"lon":50},[54,55],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},{"name":56,"role":35,"phone":10,"phoneExt":10,"email":57},"Rebecca Geer","Rebecca.Geer@cchmc.org",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[61,63,65,67,69],{"name":62,"class":6},"University of Connecticut",{"name":64,"class":6},"University of Colorado, Denver",{"name":66,"class":6},"Guy's and St Thomas' NHS Foundation Trust",{"name":68,"class":6},"Duke University",{"name":70,"class":6},"Children's Hospital of Philadelphia","100369718","hydroxyurea-exposure-limiting-pregnancy-and-follow-up-lactation-100369718",false,"NCT04093986","Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation","HELPFUL","Inclusion Criteria:\n\n* Medical records or data available from previous clinical care prior to June 20, 2019 of pregnant females with SCD, including women who miscarried, had a still birth, or completed labor at any gestational stage, with any hydroxyurea exposure during either pregnancy and\u002For while breastfeeding.\n* Medical records or data available from previous clinical care prior to June 20, 2019 about pregnancy and breastfeeding outcomes, both for babies with hydroxyurea exposure and other babies by these same women.\n\nExclusion Criteria:\n\n* Unavailable medical records or lack of information about hydroxyurea exposure.","ALL",{"count":80,"type":81},200,"ESTIMATED","OBSERVATIONAL","The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.",[85,86],"Sickle Cell Disease","Sickle Cell Anemia",[88],"Hydroxyurea","2026-06-16",{"date":91,"type":92},"2026-06-18","ACTUAL",{"date":94,"type":92},"2019-12-22",{"date":96,"type":81},"2030-12-31",{"name":5,"class":6},1]