[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579069":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":26,"overallStatus":74,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Guangdong Provincial People's Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyperbaric Oxygen group","EXPERIMENTAL","Administration of 100% oxygen at a pressure of 2.0ATA once daily for 60-90 minutes for a total of 30-40 times and administration of pressurised ice gloves 30 minutes before, during and 30 minutes after the administration of paclitaxel-based chemotherapeutic agents.",[13,14],"Device: hyperbaric oxygenation treatment","Behavioral: routine care",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","ACTIVE_COMPARATOR","Administration of pressurised ice gloves 30 minutes before, during, and 30 minutes after administering paclitaxel chemotherapy drugs.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","hyperbaric oxygenation treatment","Administration of 100% oxygen at a pressure of 2.0ATA once daily for 60-90 minutes for a total of 30-40 times.",[9],null,{"type":28,"name":29,"description":18,"armGroupLabels":30,"otherNames":26},"BEHAVIORAL","routine care",[16,9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Kun wang, Professor","CONTACT","86+13829694500","gzwangkun@126.com",[38],{"facility":5,"status":26,"city":39,"state":40,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Guangzhou","Guangdong","China","CN",{"type":44,"coordinates":45},"Point",[46,47],113.25,23.11667,{"lat":47,"lon":46},[50],{"name":51,"role":34,"phone":52,"phoneExt":26,"email":36},"Kun Wang","13922118086",{"type":54,"investigatorFullName":51,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Professor","100579069","hyperbaric-oxygen-therapy-for-peripheral-neuropathy-due-to-paclitaxel-analogs-100579069",false,"NCT06819501","Hyperbaric Oxygen Therapy for Peripheral Neuropathy Due to Paclitaxel Analogs","Inclusion Criteria:\n\n1. Patients with newly diagnosed breast cancer by pathology\n2. Age 18-60 years\n3. ECOG 0-2\n4. CIPN patients with NCI-CTCAE grade 1 or higher after treatment with paclitaxel-based drugs\n\nExclusion Criteria:\n\n1. Patients with contraindications to hyperbaric oxygen i. Untreated pneumothorax. ii. concomitant administration of disulfiram. iii. concomitant administration of antineoplastic drugs such as bleomycin, cisplatin, adriamycin. iv. premature and\u002For low body mass newborns.\n\n   iv. Premature and\u002For low body mass neonates.\n2. Other cancers","FEMALE","18 Years","60 Years",{"count":66,"type":67},226,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this study was to explore the safety and efficacy of hyperbaric oxygen in the treatment of peripheral neuropathy due to paclitaxel analogues",[73],"Breast Cancers","NOT_YET_RECRUITING","2025-02-10",{"date":77,"type":78},"2025-02-11","ACTUAL",{"date":80,"type":67},"2025-02-05",{"date":82,"type":67},"2026-09-01",{"name":5,"class":6},1]