[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100412215":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":62,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":26,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":26,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Assaf-Harofeh Medical Center","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HBOT treatment group","ACTIVE_COMPARATOR","40 daily hyperbaric oxygen treatment sessions will be administered 5 days per week",[13],"Device: Hyperbaric oxygen",{"label":15,"type":16,"description":17,"interventionNames":18},"HBOT sham group","SHAM_COMPARATOR","40 daily Sham non-hyperbaric oxygen treatment will be administered 5 days per week",[19],"Device: Sham",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Hyperbaric oxygen","Each session will include exposure of 90 minutes to 100% at 2 ATA, with 5 minutes air breaks every 20 minutes",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham","Each session will include exposure of 90 minutes to 21% at 1.2 ATA during the first five minutes of the session with the noise of circulating air, and then decrease slowly during the next five minutes to 1.03 ATA",[15],[32],{"name":33,"affiliation":34,"role":35},"Shai a Efrati, MD","Asaf-Harofhe MC","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Shani Zilberman-Itskovich, Dr.","CONTACT","97289979383","shani.zilberman@mail.huji.ac.il",{"name":43,"role":39,"phone":26,"phoneExt":26,"email":44},"Shai Efrati, Prof.","efratishai@outlook.com",[46],{"facility":47,"status":48,"city":49,"state":26,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Assaf-Harofeh medical center","RECRUITING","Ẕerifin","70300","Israel","IL",{"type":54,"coordinates":55},"Point",[56,57],34.84852,31.95731,{"lat":57,"lon":56},[60],{"name":38,"role":39,"phone":61,"phoneExt":26,"email":41},"+97289979383",{"type":35,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Shay Efrati","MD","100412215","hyperbaric-oxygen-therapy-for-post-covid-19-syndrome-100412215",false,"NCT04647656","Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome","Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome: a Prospective, Randomized, Double Blind Study.","HBOTpCOVID","Inclusion Criteria:\n\n1. Age above 18 years\n2. Reported post COVID-19 cognitive deterioration that effect quality of life and persist at least 3 months after confirmed infection.\n3. Subject willing and able to read, understand and sign an informed consent\n\nExclusion Criteria:\n\n1. Inability to attend scheduled clinic visits and\u002For comply with the study protocol\n2. History of traumatic brain injury (TBI) or any other non COVID brain pathology\n3. Active malignancy\n4. Substance use at baseline\n5. Severe or unstable physical disorders or major cognitive deficits at baseline\n6. HBOT for any reason prior to study enrolment\n7. Chest pathology incompatible with pressure changes (including moderate to severe asthma)\n8. Ear or Sinus pathology incompatible with pressure changes\n9. An inability to perform an awake brain MRI\n10. Active smoking","ALL","18 Years",{"count":76,"type":77},91,"ESTIMATED","INTERVENTIONAL",[80],"NA","Post-COVID-19 syndrome is an assembly of symptoms, following an infection with Coronavirus disease 2019 (COVID-19). The syndrome is characterized by cognitive impairment, fatigue, sleep disorders, smell and taste disorders, pain and more. This long-term sequela can last for months after recovering from the virus, and no treatment is known to date. The aim of this study is to compare the effect of HBOT vs. Sham on post COVID-19 syndrome",[83,84],"Covid19","Neurocognitive Dysfunction","2026-04-16",{"date":87,"type":88},"2026-04-21","ACTUAL",{"date":90,"type":88},"2023-06-01",{"date":92,"type":77},"2027-12-31",{"name":5,"class":6},1]