[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625559":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":28,"locations":38,"responsibleParty":73,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":18,"enrollmentInfo":89,"targetDuration":18,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Università degli Studi del Piemonte Orientale Amedeo Avogadro","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hypnotic Communication","EXPERIMENTAL","In the intervention group, adult patients (≥18 years), of both sexes, referred to the Cardiology Unit and scheduled for elective coronary angiography, who are able to read and understand Italian, will receive a session of hypnotic communication in addition to standard care.\n\nThis session will be conducted by nursing staff trained in hypnotic communication. It will begin at the patient's bedside before the procedure and continue throughout the coronary angiography, ending when the procedure is complete. The communication technique follows a structured five-phase model: pre-induction, induction, core (body), de-induction, and closure (tail). It uses empathetic, suggestive language without formal hypnosis, aiming to reduce emotional distress (such as anxiety, stress, and fear) and improve the overall patient experience.\n\nPatients may withdraw from the session at any time if they feel discomfort or no longer wish to participate.",[13],"Other: Hypnotic Communication",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Patients in the control group will receive standard of care only.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":18},"Hypnotic communication follows a process consisting of five distinct phases (Granone, 1989):\n\n1. Pre-induction\n2. Induction\n3. Core (Body)\n4. De-induction\n5. Closure (Tail)\n\nThe intervention will be delivered by nursing staff trained and experienced in hypnotic communication.\n\nThe session will begin at the patient's bedside and continue throughout the entire procedure, concluding upon its completion.",[9],[24],{"name":25,"affiliation":26,"role":27},"Simona Milani, MSN","Azienda Sanitaria Locale di Biella","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Alberto Dal Molin, Associate Professor, PhD","CONTACT","+39 0321660607","alberto.dalmolin@med.uniupo.it",{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},"Dino Stefano Di Massimo, MSN","01515153432","dinostefano.dimassimo@aslbi.piemonte.it",[39],{"facility":26,"status":40,"city":41,"state":42,"zip":43,"country":42,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Ponderano","Italy","13875","IT",{"type":46,"coordinates":47},"Point",[48,49],8.05592,45.53846,{"lat":49,"lon":48},[52,55,56,59,61,63,65,67,69,71],{"name":25,"role":31,"phone":53,"phoneExt":18,"email":54},"003901515153432","simona.milani@aslbi.piemonte.it",{"name":35,"role":31,"phone":53,"phoneExt":18,"email":37},{"name":57,"role":58,"phone":18,"phoneExt":18,"email":18},"Cinzia Rollino, RN","SUB_INVESTIGATOR",{"name":60,"role":58,"phone":18,"phoneExt":18,"email":18},"Giuseppina D'Amico, RN",{"name":62,"role":58,"phone":18,"phoneExt":18,"email":18},"Massimo Fusco, RN",{"name":64,"role":58,"phone":18,"phoneExt":18,"email":18},"Paolo Giachino, RN",{"name":66,"role":58,"phone":18,"phoneExt":18,"email":18},"Gaetana Incardona, RN",{"name":68,"role":58,"phone":18,"phoneExt":18,"email":18},"Cinzia Ravetto, RN",{"name":70,"role":58,"phone":18,"phoneExt":18,"email":18},"Manuela Tonella, RN",{"name":72,"role":58,"phone":18,"phoneExt":18,"email":18},"Chiara Gallione, PhD, MSN, RN",{"type":74,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[76],{"name":77,"class":78},"Azienda Sanitaria Locale Biella","UNKNOWN","100625559","hypnotic-communication-in-cardiology-a-randomized-controlled-trial-100625559",false,"NCT07424209","Hypnotic Communication in Cardiology: A Randomized Controlled Trial","The Effectiveness of Hypnotic Communication in Reducing Emotional Distress and Improving Patient Experience During Elective Coronary Angiography: A Monocentric Randomized Controlled Trial","IPNOCARDIO","Inclusion Criteria:\n\n* Adult patients (≥18 years), of both sexes, referred to the Cardiology Unit and scheduled for elective coronary angiography;\n* Ability to read and understand the Italian language.\n\nExclusion Criteria:\n\n* Cognitive impairment or neurodegenerative disorders that may compromise the ability to provide informed consent;\n* Psychiatric disorders, neurodegenerative diseases, or major depressive states.","ALL","18 Years",{"count":90,"type":91},306,"ESTIMATED","INTERVENTIONAL",[94],"NA","Undergoing medical procedures, especially surgical ones, is a significant source of emotional stress for patients. Emotions like anxiety, fear, anger, and depression often accompany such experiences and can negatively impact clinical outcomes. Preoperative anxiety, in particular, affects nearly half of all surgical patients and can lead to complications such as hemodynamic instability, increased medication needs, and prolonged recovery times.\n\nManaging this emotional distress is therefore a priority. While pharmacological strategies are commonly used, growing attention is being given to non-drug interventions such as music, art, and play therapies. One such technique is hypnotic communication-a method that uses empathetic, suggestion-based language to influence emotional and physical states without formal hypnotic induction. This technique has roots in anesthesiology and has shown promise in reducing pain and anxiety during medical procedures.\n\nThe proposed study aims to evaluate the effectiveness of hypnotic communication in reducing emotional distress in patients undergoing elective coronary angiography. This will be done through a randomized controlled trial involving 306 adult patients at the Cardiology Unit of the Ospedale degli Infermi in Biella, Italy.\n\nParticipants will be randomly assigned to either an experimental group receiving hypnotic communication alongside standard care, or a control group receiving standard care only. The hypnotic session, delivered by trained nurses, will begin before the procedure and continue until it ends, following a five-phase structure (pre-induction, induction, core, de-induction, and closure).\n\nThe primary outcome is the patient's emotional state-specifically stress, anxiety, depression, anger, and need for help-measured before and after the procedure using the Emotion Thermometer Tool. Secondary outcomes include post-procedural pain (measured 15 and 60 minutes after) and patient satisfaction with the communication technique.\n\nThe study is designed with a type I error rate of 0.05 and 80% statistical power, and recruitment is expected to last 24 months. Data will be anonymized, securely stored, and analyzed using appropriate statistical methods. Ethical approval and informed consent are integral parts of the protocol.\n\nBy investigating the emotional and clinical impact of hypnotic communication, the study hopes to support its integration into routine care practices, offering a simple, safe, and cost-effective method to enhance patient well-being during invasive procedures.",[97,98,99],"Psychological Distress","Pain","Anxiety",[101,102,103,98,99],"Hypnosis","Psychological distress","Coronary Angiography","2026-02-13",{"date":106,"type":107},"2026-02-20","ACTUAL",{"date":109,"type":107},"2025-06-09",{"date":111,"type":91},"2027-10-09",{"name":5,"class":6},1]