[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100232534":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":35,"centralContacts":40,"locations":49,"responsibleParty":95,"collaborators":28,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":101,"sex":107,"minAge":108,"maxAge":28,"enrollmentInfo":109,"targetDuration":28,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":28,"overallStatus":66,"whyStopped":28,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"Universität Duisburg-Essen","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Hypoglossal acupuncture","EXPERIMENTAL","Single treatment of hypoglossal needle acupuncture during the chemotherapy administration: Treated points will be Jinjin (Golden Liquid\u002FEX-HN12) left beside the lingual frenulum and Yuye (Jade Fluid\u002FEX-HN13) right beside the lingual frenulum. Both points are treated in quick succession with immediate removal of the needle.",[13],"Other: Hypoglossal acupuncture",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham acupuncture","SHAM_COMPARATOR","Single treatment of hypoglossal sham acupuncture uring the chemotherapy administration: Treated points will be 1 to 1.5 cun (a cun is defined as the width of the patient's thumb at the knuckle) beside the verum acupuncture points Jinjin and Yuye using the dull side of the needle.",[19],"Other: Sham acupuncture",{"label":21,"type":22,"description":23,"interventionNames":24},"Dietary recommendations","ACTIVE_COMPARATOR","This group adheres to specific dietary recommendations for dysgeusia of the German Cancer Society.",[25],"Behavioral: Dietary recommendations",[27,30,32],{"type":6,"name":9,"description":28,"armGroupLabels":29,"otherNames":28},null,[9],{"type":6,"name":15,"description":28,"armGroupLabels":31,"otherNames":28},[15],{"type":33,"name":21,"description":28,"armGroupLabels":34,"otherNames":28},"BEHAVIORAL",[21],[36],{"name":37,"affiliation":38,"role":39},"Gustav Dobos, Prof., MD","Center for Integrative Medicine and Health, University Hospital Essen, University of Duisburg-Essen","STUDY_DIRECTOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":28,"email":45},"Heidemarie Haller, PhD","CONTACT","+4920172377382","heidemarie.haller@uk-essen.de",{"name":47,"role":43,"phone":28,"phoneExt":28,"email":48},"Holger Cramer, PhD","holger.cramer@med.uni-tuebingen.de",[50,64,81],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":28},"Department of Gynecology & Gynecologic Oncology, Evang. Kliniken Essen-Mitte","ACTIVE_NOT_RECRUITING","Essen","North Rhine-Westphalia","45136","Germany","DE",{"type":59,"coordinates":60},"Point",[61,62],7.01228,51.45657,{"lat":62,"lon":61},{"facility":65,"status":66,"city":67,"state":28,"zip":68,"country":56,"countryCode":57,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Universitätsklinikum Mannheim, Internistische Onkologie","RECRUITING","Mannheim","68167",{"type":59,"coordinates":70},[71,72],8.46694,49.4891,{"lat":72,"lon":71},[75,78],{"name":76,"role":43,"phone":28,"phoneExt":28,"email":77},"Ralf-Dieter Hofheinz, MD","ralf-dieter.hofheinz@medma.uni-heidelberg.de",{"name":79,"role":43,"phone":28,"phoneExt":28,"email":80},"Simone Weingärtner, MD","simone.weingaertner@umm.de",{"facility":82,"status":83,"city":84,"state":28,"zip":85,"country":56,"countryCode":57,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Robert Bosch Krankenhaus Stuttgart","NOT_YET_RECRUITING","Stuttgart","70376",{"type":59,"coordinates":87},[88,89],9.17702,48.78232,{"lat":89,"lon":88},[92],{"name":93,"role":43,"phone":28,"phoneExt":28,"email":94},"Marcela Winkler, MD","Marcela.Winkler@rbk.de",{"type":96,"investigatorFullName":97,"investigatorTitle":98,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"PRINCIPAL_INVESTIGATOR","Heidemarie Haller","Postdoctoral Research Fellow","100232534","hypoglossal-acupuncture-for-dysgeusia-in-patients-undergoing-chemotherapy-100232534",false,"NCT02304913","Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy","Hypoglossal Acupuncture for Dysgeusia in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial","OralAcu","Inclusion Criteria:\n\n* Initial treatment with platinum-containing or taxane-based CTX (regardless of the the length of the CTX cycle)\n* Senological, gynecological or internistic tumors\n* Phantogeusia (on average ≥4 NRS)\n* Willingness to participate in the study and written informed consent\n\nExclusion Criteria:\n\n* Severe stomatitis\n* Dysgeusia before the CTX based on neurological diseases, diabetes, or the ingestion of drugs with taste disorders as side effects\n* Leucopenia\u002Fneutropenia\n* Intake of anticoagulants\n* Smoking\n* Severe physical or mental comorbidity (due to which the patient is unable to participate in the study)\n* Participation in other CAM treatments within the integrative oncology care\n* Participation in other studies on the effectiveness of interventions for oral complications","ALL","18 Years",{"count":110,"type":111},75,"ESTIMATED","INTERVENTIONAL",[114],"NA","This randomized controlled trial aims to investigate hypoglossal acupuncture in comparison to sham acupuncture and standard medical treatment (dietary recommendations) in the treatment of dysgeusia in cancer patients undergoing chemotherapy.",[117,118,119,120,121],"Acupuncture","Taste Disorders","Dysgeusia","Chemotherapy","Cancer","2026-04-09",{"date":124,"type":125},"2026-04-14","ACTUAL",{"date":127,"type":125},"2015-01-01",{"date":129,"type":111},"2027-12-31",{"name":5,"class":6},3]