[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621754":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":19,"responsibleParty":36,"collaborators":7,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":7,"studyType":51,"phases":7,"briefSummary":52,"conditions":53,"keywords":7,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Centro di Riferimento Oncologico - Aviano","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Valli De Re","Centro di Riferimento Oncologico","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Valli De Re, PhD","CONTACT","+39 0434 659672","vdere@cro.it",[20],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Centro di Riferimento Oncologico (CRO) di aviano-IRCCS","RECRUITING","Aviano","Pordenone","33081","Italy","IT",{"type":29,"coordinates":30},"Point",[31,32],12.59472,46.07056,{"lat":32,"lon":31},[35],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},{"type":37,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100621754","identification-of-biomarkers-of-risk-for-pre-neoplastic-and-neoplastic-lesions-for-the-development-of-gastric-cancer-100621754",false,"NCT07374731","Identification of Biomarkers of Risk for Pre-neoplastic and Neoplastic Lesions for the Development of Gastric Cancer","DSCb score","Inclusion Criteria:\n\n* Aged over 18;\n* Ability to understand, accept, and sign the informed consent form for the study;\n* Ability to understand, accept, and sign the consent form for data processing;\n* Ability to understand, accept, and sign the consent form for the collection of a serum sample for research purposes;\n* Patients who are fasting and have requested a pepsinogen test or gastroscopy, or who have gastric cancer prior to treatment;\n* Subjects who are fasting and have suspected pre-neoplastic\u002Fneoplastic gastric lesions or who have requested a pepsinogen test and for whom endoscopic examination data are available.\n\nExclusion Criteria:\n\n* Patients under the age of 18\n* Pregnant women\n* Patients with a coexisting or previous diagnosis of another malignant neoplasm in the last 5 years\n* Patients unable to understand, accept, and sign the consent form for data processing","ALL","18 Years","100 Years",{"count":49,"type":50},192,"ESTIMATED","OBSERVATIONAL","Investigator propose the implementation of circulating biomarker monitoring, focusing on molecules related to the progression of gastric atrophy and\u002For associated with gastric cancer.\n\nMonitoring these biomarkers will provide gastroenterologists with timely information on individuals at risk and, if values worsen during follow-up, will alert physicians observing these patients to evaluate them.\n\nThis monitoring will be offered to individuals who contact the IBO (Immunopatologia e Biomarcatori Oncologici) Unit at CRO (Centro di Riferimento Oncologico) in Aviano requesting an assessment of gastric function through pepsinogen and G17 gastrin level testing. Monitoring these biomarkers will provide a dynamic analysis of patients' gastric status, allowing for timely intervention in case of deviations from normal values. This proactive approach is important for the preventive management of gastric diseases, particularly for the diagnosis and monitoring of gastric atrophy and gastric cancer.\n\nThe IBO unit of the CRO in Aviano, together with the pathological anatomy and clinical units of gastroenterology, medical oncology, and surgery, will play a role in coordinating and implementing this monitoring program, thus contributing to the promotion of gastric health and the prevention of associated diseases.",[54],"Gastric Cancer","2026-01-29",{"date":57,"type":58},"2026-02-02","ACTUAL",{"date":60,"type":58},"2025-05-21",{"date":62,"type":50},"2027-01-31",{"name":5,"class":6},1]