[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100547860":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":50,"collaborators":54,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Ospedale San Raffaele","OTHER",[8,13,16,19],{"label":9,"type":10,"description":10,"interventionNames":11},"CF patients with chronic M. abscessus infection",null,[12],"Other: Luminex; scRNAsec",{"label":14,"type":10,"description":10,"interventionNames":15},"CF patients with M. abscessus pulmonary disease",[12],{"label":17,"type":10,"description":10,"interventionNames":18},"CF patients with no history of M. abscessus infection",[12],{"label":20,"type":10,"description":10,"interventionNames":21},"Healty Controls",[12],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Luminex; scRNAsec","Evaluation of specific cell populations associated with development of M. abscessus lung disease; evaluation of circulating factors related to immunoresponses",[14,9,17,20],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Nicola I Lorè, PhD","CONTACT","+390226434902","lore.nicolaivan@hsr.it",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Milan","MI","20132","Italy","IT",{"type":42,"coordinates":43},"Point",[44,45],9.18951,45.46427,{"lat":45,"lon":44},[48],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":49},"nicolaivanlore@hsr.it",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Nicola Lore","Principal Investigator",[55],{"name":56,"class":6},"Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico","100547860","identification-of-new-biological-markers-for-the-progression-of-mycobacterium-abscessus-induced-lung-disease-in-cystic-fibrosis-100547860",false,"NCT06413459","Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis","BioMol-MA","Inclusion Criteria:\n\n* Patients with a certain diagnosis of cystic fibrosis and visited during normal clinical practice, in accordance with the standard operating procedures in force at the Centres.\n* Both sexes\n* Age \\>18 years\n* Obtaining informed consent for patients (based on the procedures established by the protocol).\n\nExclusion Criteria:\n\n* Patients unable to understand the instructions and information provided and be able to adequately accept the study methods.","ALL","18 Years",{"count":67,"type":68},40,"ESTIMATED","OBSERVATIONAL","In this project the investigators aim to identify new biological markers by characterizing the response\u002Finflammation associated with the development and progression of M. abscessus lung disease in patients suffering from cystic fibrosis with the aim of increasing current knowledge available on the development and progression of lung disease.",[72,73],"Non-Tuberculous Mycobacterial Pneumonia","Cystic Fibrosis Lung",[75],"scRNASec","2024-05-14",{"date":78,"type":79},"2024-05-16","ACTUAL",{"date":81,"type":79},"2021-04-08",{"date":83,"type":68},"2027-03-30",{"name":5,"class":6},1]