[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604741":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":17,"locations":23,"responsibleParty":39,"collaborators":43,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis","OTHER",[8,11,14],{"label":9,"type":10,"description":9,"interventionNames":10},"Patients undergoing surgery at the Department of Surgery, with a diagnosis of CRC;",null,{"label":12,"type":10,"description":13,"interventionNames":10},"Subjects with a negative endoscopic examination result.","Subjects who attend our Institution's Department of Digestive Endoscopy for a colonoscopy performed for diagnostic purposes, with a negative endoscopic examination result.",{"label":15,"type":10,"description":16,"interventionNames":10},"Subjects with a diagnosis of adenoma with high-grade dysplasia, a condition considered pre-cancerous","Subjects who attend our Institution's Department of Digestive Endoscopy for a colonoscopy performed for diagnostic purposes, or patients undergoing a surgical procedure at the Department of Surgery, in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.",[18],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Pasqua Letizia Pesole, Biologist","CONTACT","+390804994365","letizia.pesole@irccsdebellis.it",[24],{"facility":25,"status":26,"city":27,"state":10,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Biobank Core Facility","RECRUITING","Castellana Grotte","70013","Italy","IT",{"type":32,"coordinates":33},"Point",[34,35],17.16549,40.88643,{"lat":35,"lon":34},[38],{"name":19,"role":20,"phone":10,"phoneExt":10,"email":22},{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Pasqua Letizia Pesole","Principal Investigator",[44],{"name":45,"class":6},"University of Bari Aldo Moro","100604741","identification-of-new-non-invasive-predictive-and-diagnostic-biomarkers-for-colorectal-cancer-100604741",false,"NCT07153458","Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer","Inclusion Criteria:\n\n* AIM 1: Patients undergoing surgery at the U.O.C. of Surgery, with a diagnosis of CRC.\n* AIM 2: Subjects without colon disease.\n* AIM 3: Subjects with adenoma and high-grade dysplasia.\n\nExclusion Criteria:\n\n* Subject with any other pathology not included in the inclusion criteria.",true,"ALL","18 Years",{"count":56,"type":57},60,"ESTIMATED","OBSERVATIONAL","The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC.\n\nIt is an observational study with 3 enrollment arms:\n\nArm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis;\n\nArm 2: Subjects with a negative result from the endoscopic examination;\n\nArm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.",[61,62],"CRC (Colorectal Cancer)","Adenoma Colon",[64,65,66,67],"crc (colorectal cancer)","Adenoma colon","Biomarkers","neoplasm","2025-12-12",{"date":70,"type":71},"2025-12-19","ACTUAL",{"date":73,"type":71},"2025-12-01",{"date":75,"type":57},"2027-12-01",{"name":5,"class":6},1]