[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546699":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":38,"locations":43,"responsibleParty":59,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":24,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":88,"overallStatus":46,"whyStopped":24,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Imperial College London","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"High Calorie, Then Low Calorie","EXPERIMENTAL","Subjects will receive an unhealthy meal that against the healthy eating guidelines. After a washout period of at least 24hours, subjects will receive a balanced diet that meets healthy eating guidelines.",[13,14],"Other: High Calorie Meal Intervention","Other: Low Calorie Meal Intervention",{"label":16,"type":10,"description":17,"interventionNames":18},"Low Calorie, Then High Calorie","Subjects will receive a balanced diet that meets healthy eating guidelines. After a washout period of at least 24hours, subjects will receive an unhealthy meal that against the healthy eating guidelines",[13,14],[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"High Calorie Meal Intervention","Subjects will receive a unhealthy meal high in calorie, sugar and fat",[9,16],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Low Calorie Meal Intervention","Subjects will receive a healthy meal with balanced macronutrient, high in vegetables and dietary fibre",[9,16],[30,34],{"name":31,"affiliation":32,"role":33},"Mingzhu Cai, PhD","Nutrition Research Section, Imperial College London","STUDY_CHAIR",{"name":35,"affiliation":36,"role":37},"Mayue Shi, PhD","Department of Electrical and Electronic Engineering, Imperial College London","PRINCIPAL_INVESTIGATOR",[39],{"name":31,"role":40,"phone":41,"phoneExt":24,"email":42},"CONTACT","+44(0)7395757128","m.cai18@imperial.ac.uk",[44],{"facility":45,"status":46,"city":47,"state":24,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"NIHR Imperial College London Clinical Research Facility","RECRUITING","London","W12 0NN","United Kingdom","UK",{"type":52,"coordinates":53},"Point",[54,55],-0.12574,51.50853,{"lat":55,"lon":54},[58],{"name":31,"role":40,"phone":41,"phoneExt":24,"email":42},{"type":60,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100546699","identifying-wearable-biomarkers-to-monitor-dietary-intake-100546699",false,"NCT06398340","Identifying Wearable Biomarkers to Monitor Dietary Intake","Identifying Physiological Biomarkers for Monitoring Dietary Behaviours","FoodSense","Inclusion Criteria:\n\n* Male or female\n* Age between 18-65 years (inclusive)\n* Body mass index (BMI) of 18-30 kg\u002Fm2\n* Willingness and ability to give written informed consent.\n* Willingness and ability to understand, to participate and to comply with the study requirements\n\nExclusion Criteria:\n\n* Outside of specified age and BMI range\n* Chronic medical conditions including for eating disorders, diabetes, obesity, hypertension, cancer, acute infectious disease, renal disease, cardiovascular disease, and chronic gastrointestinal condition.\n* Taking part in another research study or donating any blood in the last 3 months",true,"ALL","18 Years","65 Years",{"count":74,"type":75},10,"ESTIMATED","INTERVENTIONAL",[78],"NA","Background: Measuring what people eat is a challenge in nutrition research. Traditional methods, like food diaries, rely on self-reporting of individuals, and suffer from poor accuracy and recall bias.\n\nAims: This project aims to identify physiological biomarkers related to food and energy intake, which may be used to develop an objective tool to estimate individuals' food intake in future. Eating behaviours are accompanied by significant physiological changes such as skin temperature, blood oxygen saturation, pulse rate etc. The investigators intend to investigate whether monitoring these physiological changes can help us estimate eating behaviour, such as meal size, eating speed, and duration of meals.\n\nStudy design: Ten healthy adults will be invited for two study visits at NIHR Imperial Clinical Research Facility. Each visit will last for approximately 2 hr. They will consume a high- and low-calorie meal designed by nutritional researchers in a randomised order. During eating events, the investigators will track their physiological changes via a bedside monitor and wearable sensors. Blood samples will be taken from participants to measure their glycaemic response. Associations between energy load, glycaemic response, and physiological changes will be investigated. Our findings may promote an accelerated development of a wearable tool for dietary assessment in future.",[81,82,83,84,85,86,87],"Energy Intake","Metabolism","Digestion","Wearables","Dietary Intake Assessment","Healthy Volunteers","Blood Glucose",[89,90,91,92],"Dietary intake monitoring","wearable sensors","digital health","blood glucose","2025-02-17",{"date":95,"type":96},"2025-02-18","ACTUAL",{"date":98,"type":96},"2024-08-19",{"date":100,"type":75},"2025-07-31",{"name":5,"class":6},1]