[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590355":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":27,"locations":37,"responsibleParty":61,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":10,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8,12,15,18,21,24],{"label":9,"type":10,"description":11,"interventionNames":10},"Non-Burned Individuals in Low Humidity Environment",null,"Non-burned individuals will perform up to three work:rest cycles in a heated environment with low humidity, with each work:rest cycle lasting up to 50 minutes.",{"label":13,"type":10,"description":14,"interventionNames":10},"Moderate Burned Individuals in Low Humidity Environment","Individuals with moderate sized burn injuries will perform up to three work:rest cycles in a heated environment with low humidity, with each work:rest cycle lasting up to 50 minutes.",{"label":16,"type":10,"description":17,"interventionNames":10},"Large Burned Individuals in Low Humidity Environment","Individuals with large sized burn injuries will perform up to three work:rest cycles in a heated environment with low humidity, with each work:rest cycle lasting up to 50 minutes.",{"label":19,"type":10,"description":20,"interventionNames":10},"Non-Burned Individuals in High Humidity Environment","Non-burned individuals will perform up to three work:rest cycles in a heated environment with high humidity, with each work:rest cycle lasting up to 50 minutes.",{"label":22,"type":10,"description":23,"interventionNames":10},"Moderate Burned Individuals in High Humidity Environment","Individuals with moderate sized burn injuries will perform up to three work:rest cycles in a heated environment with high humidity, with each work:rest cycle lasting up to 50 minutes.",{"label":25,"type":10,"description":26,"interventionNames":10},"Large Burned Individuals in HIgh Humidity Environment","Individuals with large sized burn injuries will perform up to three work:rest cycles in a heated environment with high humidity, with each work:rest cycle lasting up to 50 minutes.",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Craig Crandall, PhD","CONTACT","214-345-4623","craigcrandall@texashealth.org",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Erin Harper, BS","214-345-4737","erinharper2@texashealth.org",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"IEEM Texas Health Presbyterian Hospital Dallas","RECRUITING","Dallas","Texas","75231","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-96.80667,32.78306,{"lat":50,"lon":49},[53,55,59],{"name":34,"role":30,"phone":35,"phoneExt":10,"email":54},"erinharper@texashealth.org",{"name":56,"role":30,"phone":57,"phoneExt":10,"email":58},"Courtney Kirby, RN","214-345-6502","courtneykirby@texashealth.org",{"name":29,"role":60,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":60,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Craig Crandall","Principal Investigator",[65],{"name":66,"class":6},"Texas Health Resources","100590355","ieem--workrest-cycles-in-burn-survivors--humidity-100590355",false,"NCT06966336","IEEM- Work:Rest Cycles in Burn Survivors- Humidity","Inclusion Criteria for Non-burned Individuals:\n\n* Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants must be between the ages of 18 and 65.\n\nExclusion Criteria for Non-burned Individuals:\n\n* Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg\u002Fm2 will likewise be excluded. Participants must not have had a serious burn injury requiring more than 1 night stay in the hospital.\n\nInclusion Criteria for Individuals with up to 40% of their body surface area burned (moderate burn group):\n\n\\- Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants who have sustained a burn injury must have a burn covering 20-40% of their body surface area and 50% of those burns must be full-thickness burns requiring skin grafts. Participants must be between the ages of 18 and 65.\n\nExclusion Criteria for Individuals with up to 40% of their body surface area burned (moderate burn group):\n\n\\- Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg\u002Fm2 will likewise be excluded.\n\nInclusion Criteria for Individuals with greater than 40% of their body surface area burned (large burn group):\n\n\\- Participants must be free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram. Participants who have sustained a burn injury must have a burn covering more than 40% of their body surface area and 50% of those burns must be full-thickness burns requiring skin grafts. Participants must be between the ages of 18 and 65.\n\nExclusion Criteria for Individuals with greater than 40% of their body surface area burned (large burn group):\n\n\\- Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, lung disease, etc.; as well as serious abnormalities detected on routine screening. Current smokers, as well as individuals who regularly smoked within the past 3 years will be excluded. Participants may also be excluded if body mass index is ≥ 31 kg\u002Fm2 will likewise be excluded.",true,"ALL","18 Years","65 Years",{"count":78,"type":79},70,"ESTIMATED","OBSERVATIONAL","The purpose of this project is to identify the effects of a severe burn injuries in humans on core temperature responses during work:rest cycles while in a heated environment.",[83,84],"Hyperthermia","Burn Injury",[86,87,88,89,90,91,92],"Burn Survivor","Burn","humid","dry","core temperature","heat","body temperature","2025-08-19",{"date":95,"type":96},"2025-08-26","ACTUAL",{"date":98,"type":96},"2025-08-15",{"date":100,"type":79},"2031-08-01",{"name":5,"class":6},1]