[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100363586":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":58,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Imperial College Healthcare NHS Trust","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with multi-vessel coronary artery disease (MVCAD)",null,"iFR measurements will be taken pre-operatively during the invasive coronary angiography.",[13],"Procedure: Coronary artery bypass grafting surgery (CABG)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Coronary artery bypass grafting surgery (CABG)","Patients with MVCAD will undergo CABG as per standard of care.",[9],[21],{"name":22,"affiliation":5,"role":23},"Prakash P Punjabi, MBBS,MCh,FRCS,FFST,FESC,FCCP","PRINCIPAL_INVESTIGATOR",[25,30],{"name":22,"role":26,"phone":27,"phoneExt":28,"email":29},"CONTACT","020 3313 2026","+44","P.Punjabi@imperial.ac.uk",{"name":31,"role":26,"phone":27,"phoneExt":28,"email":32},"Panagiotis G Kyriazis, BSc, MRes","Panagiotis.Kyriazis@nhs.net",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Imperial College Healthcare NHS Trust - Hammersmith Hospital","RECRUITING","London","Greater London","W12 0HS","United Kingdom","UK",{"type":43,"coordinates":44},"Point",[45,46],-0.12574,51.50853,{"lat":46,"lon":45},[49,53,54,56],{"name":50,"role":26,"phone":51,"phoneExt":28,"email":52},"Becky Ward","02075949459","becky.ward@imperial.ac.uk",{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"name":31,"role":55,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":57,"role":55,"phone":10,"phoneExt":10,"email":10},"Jaspal Kooner, MD, FRCP",{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Prakash Punjabi","Consultant Cardiothoracic Surgeon","100363586","ifr-guided-coronary-artery-bypass-grafting-surgery-100363586",false,"NCT04014140","iFR Guided Coronary Artery Bypass Grafting Surgery","Long-term Graft Patency Outcomes of LIMA-LAD Post-CABG Surgery Based on iFR Measurements.","iCABG","INCLUSION CRITERIA\n\n1. Age of 25 to 80 years of age\n2. Willing to participate and able to understand, read and sign the informed consent form (ICF) before standard of care elective CABG surgery\n3. Undergoing isolated first-time elective CABG surgery\n4. Available pre-operative angiography data with iFR measurements done during the pre-operative angiography\n\nEXCLUSION CRITERIA\n\n1. Emergency CABG surgery\n2. Ejection Fraction≤ 40%\n3. Severe valvular heart disease","ALL","25 Years","80 Years",{"count":74,"type":75},100,"ESTIMATED","OBSERVATIONAL","The expected outcome of better and improved patency of bypass grafts and its direct relation to pre-operative iFR measurements of stenosis as compared to direct visual physiology of stenosis in the coronary angiogram.\n\nTo establish the correlation between the use of intracoronary physiology and improved graft patency at 12 months for patients undergoing CABG surgery.\n\nIt is a minimum of 28 and a maximum of 100 patients single-centre proof or concept\u002F observational study\u002F pilot study.",[79,80,81],"Ischaemic Heart Disease","Coronary Artery Disease","Coronary Stenosis",[83,84],"Instantaneous wave-free ratio (iFR)","Coronary Artery Bypass Grafting (CABG)","2023-11-20",{"date":87,"type":88},"2023-11-21","ACTUAL",{"date":90,"type":88},"2022-04-25",{"date":92,"type":75},"2026-08-31",{"name":60,"class":6},1]