[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629524":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":26,"responsibleParty":40,"collaborators":26,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":26,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":26,"enrollmentInfo":52,"targetDuration":26,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":26,"overallStatus":61,"whyStopped":26,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":26},{"fullName":5,"class":6},"Aga Khan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group B","EXPERIMENTAL","Intervention group in which genicular nerves radiofrequency ablation will be done with the help ultrasound guidance.",[13],"Procedure: Ultrasound Guided",{"label":15,"type":16,"description":17,"interventionNames":18},"Group A","ACTIVE_COMPARATOR","Control group in which genicular nerves radiofrequency ablation will be done with the help of fluoroscopic guidance.",[19],"Procedure: Fluoroscope Guided",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound Guided","Genicular nerves radiofrequency ablation will be done with the help of ultrasound guidance.",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Fluoroscope Guided",[15],[31],{"name":32,"affiliation":5,"role":33},"Ali Sarfraz Siddiqui, MBBS-FCPS","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":38,"email":39},"CONTACT","+92 021-38104397","4397","sarfraz.siddiqui@aku.edu",{"type":33,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Ali Sarfraz Siddiqui","Associate Professor","100629524","image-guided-genicular-nerve-radiofrequency-ablation-for-chronic-knee-osteoarthritis-100629524",false,"NCT07475793","Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis","Efficacy of Ultrasound vs Fluoroscopy Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Both gender patients of age more than 50 years.\n* Radiographic diagnosis of knee OA with KL level 3 and 4.\n* Chronic knee pain for more than 6 months\n* Patients with more than 50% reduction in pain intensity after diagnostic genicular nerve block\n\nExclusion Criteria:\n\n* Lack of consent\n* surgery of knee\n* Patient with BMI more than 40kg\u002Fm2\n* Intra-articular steroid injection or hyaluronic acid in last 3 months\n* Localized infection at procedure site or knee.\n* Patient unable to communicate properly (Severe psychiatric illness, severe dementia and cognitive impairment).\n* Patients have moderate to severe low back pain (NRS ≥5)","ALL","50 Years",{"count":53,"type":54},52,"ESTIMATED","INTERVENTIONAL",[57],"NA","The goal of this prospective randomized control trial is to provide continued pain relief, classically long-lasting 3 to12 months, and enhanced function in patients following: both gender; male and female, age group; \\>50yr, healthy volunteers along with Radiographic diagnosis of knee OA with KL grade 3 and 4 in addition of Chronic knee pain ≥ 6 months and patients with ≥50% decrease in pain strength after diagnostic genicular nerve block. The main question it aims to answer is:\n\nIs ultrasound-guided genicular nerve RFA more efficient in lowering pain intensity at six months contrasted with fluoroscopic guided method in patients with chronic knee osteoarthritis? Researchers will compare Group A (Fluoroscopic) to Group B (Ultrasound) to see comparison in efficiency of ultrasound guided against fluoroscopic guided genicular nerves block for decrease in pain intensity and functional improvement.",[60],"Chronic Knee Osteoarthritis","NOT_YET_RECRUITING","2026-03-24",{"date":64,"type":65},"2026-03-27","ACTUAL",{"date":67,"type":54},"2026-05-01",{"date":69,"type":54},"2027-05-31",{"name":5,"class":6}]