[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100447160":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":35,"responsibleParty":67,"collaborators":10,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":84,"studyType":85,"phases":10,"briefSummary":86,"conditions":87,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Respiratory Disease",null,"Any physician-diagnosed lung disease",[13],"Diagnostic Test: 1H and Xe-129 MRI",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy","Healthy control with no physician-diagnosed lung disease",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","1H and Xe-129 MRI","Traditional 1H-MRI (room air inhalation) and Xe-129 MRI (requires inhalation of Xenon 129 gas).",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Jonathan Rayment, MDCM, MSc","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Rodrigo Sandoval, MSc","CONTACT","6048752345","2928","Rodrigo.Sandoval@bcchr.ca",[36,57],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"British Columbia Children's Hospital","RECRUITING","Vancouver","British Columbia","V6H 3N1","Canada","CA",{"type":45,"coordinates":46},"Point",[47,48],-123.11934,49.24966,{"lat":48,"lon":47},[51,52,56],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},{"name":53,"role":31,"phone":32,"phoneExt":54,"email":55},"Alam Lakhani","7606","alam.lakhani@cw.bc.ca",{"name":26,"role":27,"phone":10,"phoneExt":10,"email":10},{"facility":58,"status":38,"city":39,"state":40,"zip":59,"country":42,"countryCode":43,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"St. Paul's Hospital","V6Z 1Y6",{"type":45,"coordinates":61},[47,48],{"lat":48,"lon":47},[64],{"name":65,"role":66,"phone":10,"phoneExt":10,"email":10},"Don Sin, MD MPH","SUB_INVESTIGATOR",{"type":27,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jonathan Rayment","Clinical Assistant Professor","100447160","imaging-measures-of-respiratory-health-registry-100447160",false,"NCT05102825","Imaging Measures of Respiratory Health Registry","iMRH","Respiratory Disease\n\nInclusion Criteria:\n\n1. Physician-diagnosed lung disease - based on a diagnosis made by a treating staff physician and confirmed by the principal investigator.\n2. Age 0-99 years.\n3. Informed consent by participant, parent, or legal guardian\n4. In the opinion of the Investigator, the participant will likely be able to perform maneuvers to obtain technically acceptable pulmonary XeMRI images.\n\nExclusion Criteria:\n\n1. Physical findings at screening that, in the opinion of the Investigator, would compromise the safety of the participant or the quality of the research data.\n2. Requirement of supplementary oxygen to maintain an oxygen saturation above 95%.\n3. Failed MRI screening form.\n4. History of claustrophobia.\n5. Known current pregnancy or lactation.\n\nHealthy\n\nInclusion Criteria:\n\n1. Age 0-99 years\n2. Informed consent by participant, parent, or legal guardian\n3. In the opinion of the Investigator, the participant will likely be able to perform maneuvers to obtain technically acceptable pulmonary MRI images.\n\nExclusion Criteria\n\n1. Physician-diagnosed lung disease.\n2. Failed MRI screening form.\n3. History of claustrophobia.\n4. Physical findings at screening that, in the opinion of the Investigator, would compromise the safety of the participant or the quality of the research data.\n5. Known current pregnancy or lactation.",true,"ALL","0 Years","99 Years",{"count":82,"type":83},1000,"ESTIMATED","10 Years","OBSERVATIONAL","This is a prospective, observational cohort registry that aims to collect data on pulmonary structure and function in healthy people and those with respiratory disease, using structural and functional pulmonary 1H-MRI and hyperpolarized 129Xe-MRI.\n\nOutcome measures generated from MRI may include but are not limited to measures of regional ventilation, pulmonary microarchitecture, and regional gas exchange. Additionally, one of the goals of the registry is to facilitate the development of novel image analysis techniques that have not yet been invented.\n\nThese data will be stored along with demographic data, clinical data, and pulmonary function testing (PFT) data.\n\nThis is an open registry. Eligible local and international investigators\u002Finstitutions can apply for access.",[9,15],"2021-10-29",{"date":90,"type":91},"2021-11-02","ACTUAL",{"date":93,"type":91},"2020-06-11",{"date":95,"type":83},"2045-06-01",{"name":5,"class":6},2]