[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553713":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":68,"collaborators":70,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":10,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":10,"enrollmentInfo":85,"targetDuration":10,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University of Zurich","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mammography finding",null,"Describes the mammography finding in patients prior breast surgery",[13],"Diagnostic Test: Experimental Intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Bellona","Describes the finding in the breast tissue samples",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","Experimental Intervention","Mammography in the radiology department is commonly performed using General Electrics Medical Systems Senographe Essential device",[15,9],[25],"control intervention",[27],{"name":28,"affiliation":29,"role":30},"Thomas Frau, Prof","University Hospital Zurich, DIR","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Thomas Frauenfelder, Prof","CONTACT","+41 44 255 93 83","thomas.frauenfelder@usz.ch",{"name":38,"role":34,"phone":39,"phoneExt":10,"email":40},"Judith Jehle","0763257051","judith.jehle@usz.ch",[42,61],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"University Hospital Zurich - Diagnostic Radiology","RECRUITING","Zurich","Canton of Zurich","8091","Switzerland","CH",{"type":51,"coordinates":52},"Point",[53,54],8.55,47.36667,{"lat":54,"lon":53},[57,60],{"name":58,"role":34,"phone":59,"phoneExt":10,"email":36},"Thomas Frauenfelder, PD MD","0041442551111",{"name":33,"role":30,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":44,"city":45,"state":10,"zip":10,"country":48,"countryCode":49,"cosmosGeoPoint":62,"geoPoint":64,"contacts":65},{"type":51,"coordinates":63},[53,54],{"lat":54,"lon":53},[66],{"name":67,"role":30,"phone":10,"phoneExt":10,"email":10},"Thomas Frauenfelder, MD",{"type":69,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[71,73],{"name":72,"class":6},"Center for Proton Therapy, Paul Scherrer Institute, Villigen,Switzerland",{"name":74,"class":75},"GratXray AG","UNKNOWN","100553713","imaging-quality-and-potential-clinical-relevance-of-phase-contrast-mammography-in-vivo-a-single-center-prospective-study-100553713",false,"NCT06489665","Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study","Imaging Quality and Potential Clinical Relevance of Phase Contrast","Inclusion Criteria:\n\n* Inclusion criteria -Phase 0:\n\n  * \\>18 years\n  * Mastectomy, tumorectomy or biopsy planned\n  * Informed consent of the patient\n\nInclusion criteria -Phase 1:\n\n* \\>18 years\n* BI-RADS 5 (highly suggestive of malignancy at ultrasound or mammography) or 6 (known biopsy proven malignancy);\n* Scheduled for mastectomy or breast conserving surgery with radiotherapy.\n* Informed consent of the patient\n\nInclusion criteria - Phase 2:\n\n* \\>40 years\n* undergoing mammography for screening or diagnostic purpose.\n* Informed consent of the patient\n\nExclusion Criteria:\n\n* Exclusion criteria for all three Phases:\n\n  * Breast implants. The women will be asked, if they have a breast-implant.\n  * Inability to understand the study procedure due to cognitive or linguistic deficits.\n\nExclusion criteria for patients, participating in Phase 1 and Phase 2:\n\n* Pregnancy\n* Breast-feeding.\n* Re-staging after neoadjuvant chemotherapy. Patients who participated in prior research projects with ionizing radiation in the past 12 months","ALL","18 Years",{"count":86,"type":87},350,"ESTIMATED","OBSERVATIONAL","Conventional mammography, breast sonography and breast MRI have specific weaknesses. In particular, mammography has a low sensitivity for the detection of mammary carcinoma in patients with a dense breast. Phase contrast mammography could help to overcome some of these limitations. Observational study.",[91,92,93],"Breast Cancer","Microcalcification","Image",[95],"Mammography","2025-02-02",{"date":98,"type":99},"2025-02-05","ACTUAL",{"date":101,"type":99},"2024-10-17",{"date":103,"type":87},"2030-09-01",{"name":5,"class":6},2]