[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626911":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":36,"locations":41,"responsibleParty":60,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":10,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"P. Herzen Moscow Oncology Research Institute","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with morbidity and mortality",null,"Patients who suffered from any type of morbidity after surgery",[13],"Procedure: Proximal Gastrectomy",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients without morbidity and mortality","Patients who did not suffered from any type of morbidity after surgery",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Proximal Gastrectomy","Resection of the upper third to one-half of the stomach and the distal portion of the esophagus with different types of digestive system reconstruction",[9,15],[25,29,32,34],{"name":26,"affiliation":27,"role":28},"Andrey Ryabov, MD, PhD","P.Herzen Moscow Oncological Research Institute","STUDY_DIRECTOR",{"name":30,"affiliation":27,"role":31},"Vladimir Khomyakov, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":33,"affiliation":27,"role":31},"Nuriddin Abdulkhakimov, PhD",{"name":35,"affiliation":27,"role":31},"Pavel Smirnov",[37],{"name":26,"role":38,"phone":39,"phoneExt":10,"email":40},"CONTACT","+7 (495) 150-11-22","ryabovdoc@mail.ru",[42],{"facility":27,"status":43,"city":44,"state":10,"zip":10,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Moscow","Russia","RU",{"type":48,"coordinates":49},"Point",[50,51],37.61781,55.75204,{"lat":51,"lon":50},[54,55,58],{"name":26,"role":38,"phone":10,"phoneExt":10,"email":10},{"name":56,"role":57,"phone":10,"phoneExt":10,"email":10},"Ilya Kolobaev, PhD","SUB_INVESTIGATOR",{"name":59,"role":57,"phone":10,"phoneExt":10,"email":10},"Anton Kollontai",{"type":31,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Andrey Ryabov","Head of Department of Thoracoabdominal Oncology",[64],{"name":65,"class":66},"A.Loginov Moscow Clinical Scientific Center","UNKNOWN","100626911","immediate-and-functional-results-of-different-types-of-reconstructions-after-proximal-gastrectomy-for-gastric-and-esophagogastric-junction-cancer-100626911",false,"NCT07441785","Immediate and Functional Results of Different Types of Reconstructions After Proximal Gastrectomy For Gastric and Esophagogastric Junction Cancer","PROXISTAT","Inclusion Criteria:\n\n* All consecutive patients with clinically documented primary Gastric or Esophagogastric Junction malignancy (including Siewert I and II) cT1-3N0-2M0 undergoing proximal gastrectomy with curative intent - via open, laparoscopic or robotic approach between 01th January 2025 and 31th December 2026\n\nExclusion Criteria:\n\n* Patients with clinical evidence of metastatic disease, including positive peritoneal cytology on a previous staging laparoscopy, or those with known synchronous other cancers.\n* Esophagogastric Junction Siewert I malignancy\n* Patients submitted to Emergency surgery or surgery without curative intent\n* Patients undergoing any other surgery in addition to the curative surgery for primary Esophageal or Esophagogastric Junction malignancy\n* Patients who have previously undergone surgery on the stomach or colon","ALL","18 Years",{"count":77,"type":78},400,"ESTIMATED","OBSERVATIONAL","Proximal gastric and esophagogastric junction cancers comprise up to 40% of gastric malignancies. For localized disease, proximal gastrectomy is the main radical procedure, but reconstruction of GI tract often leads to significant functional issues.\n\nRising use of proximal resections and broader indications have increased attention to postoperative quality of life (QoL). Common reconstructions include direct esophagogastrostomy (various types), double-tract reconstruction, jejunal interposition, and newer anti-reflux anastomoses (e.g., double-flap, overlap, tunnel techniques).\n\nEach method has unique pros and cons regarding reflux esophagitis, food passage, dumping syndrome, nutritional changes, and long-term QoL.\n\nNo consensus exists on the optimal technique, leading to variable practices and outcomes. Most research focuses on oncologic radicality and survival, while functional results and QoL remain understudied.\n\nSystematic evaluation of functional outcomes across reconstruction types after proximal subtotal gastrectomy is needed in Russian Federation to improve QoL, advance research, and standardize treatment of proximal gastric and EGJ cancers.",[82,83,84],"Gastric Cancer (GC)","Siewert Type III Adenocarcinoma of Esophagogastric Junction","Siewert Type II Adenocarcinoma of Esophagogastric Junction",[86,87,88,89,90,91],"Proximal gastrectomy","Morbidity","Mortality","Quality of life","Surgery","Esophagogastric Junction Cancer","2026-04-17",{"date":94,"type":95},"2026-04-22","ACTUAL",{"date":97,"type":95},"2025-01-01",{"date":99,"type":78},"2029-06-01",{"name":5,"class":6},1]