[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602565":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":31,"responsibleParty":51,"collaborators":20,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":20,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":20,"enrollmentInfo":63,"targetDuration":20,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":77,"overallStatus":34,"whyStopped":20,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Chile","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"VR-based Cognitive Rehabilitation","EXPERIMENTAL","Participants receive cognitive rehabilitation supported by immersive virtual reality using the Meta Quest 3 headset and the Kinesix XR application. Each session lasts 60 minutes, with the first 30 minutes involving VR-based cognitive tasks supervised by an occupational therapist. A total of ten sessions are completed over a period of approximately four weeks, with a frequency of two to three sessions per week. This arm is designed to assess the feasibility, safety, usability, and preliminary effects of VR-assisted rehabilitation in patients with post-stroke cognitive impairment.",[13],"Device: Kinesix XR on Meta Quest 3",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Kinesix XR on Meta Quest 3","Participants receive cognitive rehabilitation using immersive virtual reality through the Meta Quest 3 headset and the Kinesix XR application. Each session lasts one hour, with the first 30 minutes involving VR-based tasks guided by an occupational therapist. The intervention consists of a total of ten sessions, delivered two to three times per week. The VR component is integrated into the standard outpatient cognitive rehabilitation program. The study aims to evaluate the feasibility, safety, and acceptability of using this device during therapy.",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Natalia Gattini, MD","CONTACT","+56989019110","ngattini@hcuch.cl",{"name":28,"role":24,"phone":29,"phoneExt":20,"email":30},"Diego Elizondo, MD","+56951087567","diegoelizondo@ug.uchile.cl",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":20,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Hospital Clinico de la Universidad de Chile","RECRUITING","Independencia","Santiago Metropolitan","Chile","CL",{"type":40,"coordinates":41},"Point",[42,43],-70.66647,-33.41167,{"lat":43,"lon":42},[46,47,48,50],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},{"name":28,"role":24,"phone":29,"phoneExt":20,"email":30},{"name":23,"role":49,"phone":20,"phoneExt":20,"email":20},"PRINCIPAL_INVESTIGATOR",{"name":28,"role":49,"phone":20,"phoneExt":20,"email":20},{"type":49,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Natalia Gattini","Asistant professor","100602565","immersive-virtual-reality-in-cognitive-rehabilitation-of-patients-with-post-stroke-cognitive-impairment-100602565",false,"NCT07125170","Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment","Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment: A Pilot Study at the Department of Physical Medicine and Rehabilitation, Clinical Hospital of the University of Chile","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients with a cerebrovascular accident of any etiology with less than 3 months of progression\n* Patients with mild to moderate cognitive impairment post-stroke (impairment in at least one cognitive domain)\n* MoCA score of less than 24 points\n* Referred for cognitive rehabilitation at the Occupational Therapy Unit of HCUCH\n\nExclusion Criteria:\n\n* Patients with refractive errors that prevent the use of the headset\n* Patients with any type of aphasia that prevents the administration of the MoCA test\n* Patients with severe psychiatric disorders (presence of psychotic symptoms or derealization)\n* Patients with severe motor impairments (lack of trunk control or global strength of both upper limbs \\\u003C M3)","ALL","18 Years",{"count":64,"type":65},20,"ESTIMATED","INTERVENTIONAL",[68],"NA","This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy. Participants will use a head-mounted display and interactive software to engage in gamified cognitive exercises that simulate memory, attention, and executive function tasks. The intervention consists of 10 sessions, delivered two to three times per week over a period of approximately four weeks. The study will assess multiple feasibility indicators, including the recruitment rate based on eligibility criteria, the safety and tolerability of VR sessions for participants, and the usability and satisfaction reported by occupational therapists administering the intervention. Additionally, exploratory outcomes include changes in global cognition and specific cognitive domains, as well as self-reported quality of life. Adverse effects related to VR use will be tracked. This pilot study will help inform the design and implementation of future, larger-scale clinical trials.",[71,72,73,74,75,76],"Stroke","Post-Stroke Cognitive Impairment (PSCI)","Cognitive Dysfunction","Virtual Reality Therapy","Virtual Reality Cognitive Training","Cognitive Rehabilitation",[78,79,80,81,82,83,84,85],"virtual reality","Cognitive rehabilitation","Immersive Therapy","Meta Quest 3","Kinesix XR","Occupational Therapy","Montreal Cognitive Assessment (MoCA)","Simulator Sickness Questionnaire (SSQ)","2025-08-08",{"date":88,"type":89},"2025-08-15","ACTUAL",{"date":91,"type":89},"2025-08-06",{"date":93,"type":65},"2026-05-01",{"name":5,"class":6},1]