[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596076":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":46,"collaborators":18,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":33,"whyStopped":18,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Consorci Sanitari de Terrassa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Immersive VR-Based Multimodal Intervention (Virtual-METS)","EXPERIMENTAL","Participants in this arm will receive a multimodal group-based intervention using immersive virtual reality (IVR) without headsets. The intervention includes mindfulness (10 minutes), cognitive training (30 minutes), and physical exercises (20 minutes) delivered through MK360 immersive technology. Sessions are conducted in groups of 5 participants, twice per week for 12 weeks (24 sessions in total), led by a neuropsychologist.",[13],"Behavioral: Immersive VR-Based Multimodal Intervention (Virtual-METS)",{"label":15,"type":16,"description":17,"interventionNames":18},"No Intervention: Treatment as Usual (Control Group)","NO_INTERVENTION","Participants in this arm will continue with their usual care, including routine medical visits and remotely administered psychoeducational guidelines to support diet, physical activity, and adherence to pharmacological treatment. They will not receive any specific intervention during the study period.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Immersive VR-Based Multimodal Intervention (Virtual-METS)","This intervention consists of a 12-week, group-based program using immersive virtual reality technology (MK360) without head-mounted displays. Each 60-minute session combines mindfulness practices adapted from the Mindfulness-Based Stress Reduction (MBSR) program, cognitive training targeting attention, processing speed, memory, and executive function through realistic virtual environments (such as parks, markets, or home interiors), and chair-based physical exercises focused on balance, stretching, and muscle strengthening. The intervention is delivered in small groups of five participants, twice per week, for a total of 24 sessions, and is led by a trained neuropsychologist.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Maite Garolera","CONTACT","+34937310007","mgarolera@cst.cat",[32],{"facility":5,"status":33,"city":34,"state":18,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Terrassa","08227","Spain","ES",{"type":39,"coordinates":40},"Point",[41,42],2.01667,41.56667,{"lat":42,"lon":41},[45],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},{"type":47,"investigatorFullName":27,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Principal Investigator of the Brain, Cognition, and Behavior Research Group (C3-CST).","100596076","immersive-virtual-reality-training-for-improving-cognition-in-adults-with-metabolic-syndrome-100596076",false,"NCT07040748","Immersive Virtual Reality Training for Improving Cognition in Adults With Metabolic Syndrome","Multimodal Immersive Virtual Reality Training for Improving Cognition in Adults With Metabolic Syndrome: A Randomized Clinical Trial","VIRTUAL-METS","Inclusion Criteria:\n\n* Demonstrated criteria for the MetS: central obesity (waist circumference ≥ 94 cm for men or ≥ 80 cm for women) and at least 2 of the criteria described as follow: Triglycerides ≥ 150 mg\u002Fdl or specific treatment of this lipid disorder; HDL-C \\\u003C 40 mg\u002Fdl (men) or \\\u003C 50 mg\u002Fdl (women) or specific treatment of this lipid disorder; Systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 85 mmHg or previously diagnosed hypertension treatment; Basal glycemia ≥ 100 mg\u002Fdl or type 2 diabetes previously diagnosed).\n* Age: between 45 and 70 years old.\n* Subjective cognitive complaints: Subjective Cognitive Decline Questionnaire (≥ 7).\n* Ability to fully understand and speak Spanish or Catalan.\n\nExclusion Criteria:\n\n* Confirmed or suspicion of dementia (MMSE\\\u003C24).\n* Diagnosis of severe psychiatric, neurological, developmental disorders, systemic pathologies, hematological, hormonal, nutritional pathology, and\u002For neoplasm that are known to cause cognitive deficits.\n* Other severe comorbidities considered a probable bias for the study: a cardiac history of unstable angina, recent myocardial infarction within the last 3 months, congestive heart failure, significant heart valve dysfunction, or unstable hypertension; taking medications that could negatively affect cognitive function.\n* Physical, motor, or sensory alterations that impede the neuropsychological examination or the rehabilitation program.","ALL","45 Years","70 Years",{"count":61,"type":62},84,"ESTIMATED","INTERVENTIONAL",[65],"NA","This study aims to evaluate the effectiveness of a multimodal intervention using immersive virtual reality (Virtual-METS) to improve cognitive function in middle-aged adults with metabolic syndrome and subjective cognitive complaints. The intervention combines cognitive training and physical exercise in group sessions over 12 weeks.",[68],"Metabolic Syndrome",[70,71,72,73],"Metabolic syndrome","Cognitive impairment","Virtual Reality","Cognitive Training","2025-06-26",{"date":76,"type":77},"2025-06-27","ACTUAL",{"date":79,"type":77},"2025-03-01",{"date":81,"type":62},"2027-04-01",{"name":5,"class":6},1]