[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527988":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":34,"responsibleParty":54,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Healing Ulcer",null,"The patients will be recruited from the doctors and the nurses of the foot clinic of Department of Endocrinology. A complete medical history and physical parameters will be collected, moreover a peripheral circulation status will assess at the time of the enrolment. During the first visit blood samples and a biopsy from the site of foot ulcers will be taken together with a picture of the ulcer. All patients will follow the medical treatments, as recommended by the multidisciplinary clinical team (for example revascularization or ulcer debriding). Intervals between visits will range between 4 to 8 weeks according to the usual medical routine. During visits 1, 2 and 3 the ulcers status will be documented by pictures, physical parameter collected, biopsies, ulcer fluid and blood samples will be taken for further analysis.\n\nAt visit 3 the ulcers will be classified as \"healing\" if completely resolved or dramatically reduced (more than 50%), otherwise will be classified as \"non-healing\".",[13],"Other: medical treatments",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-Healing Ulcer","The patients will be recruited from the doctors and the nurses of the foot clinic of Department of Endocrinology. A complete medical history and physical parameters will be collected, moreover a peripheral circulation status will assess at the time of the enrolment. During the first visit blood samples and a biopsy from the site of foot ulcers will be taken together with a picture of the ulcer. All patients will follow the medical treatments, as recommended by the multidisciplinary clinical team (for example revascularization or ulcer debriding). Intervals between visits will range between 4 to 8 weeks according to the usual medical routine. During visits 1, 2 and 3 the ulcers status will be documented by pictures, physical parameter collected, biopsies, ulcer fluid and blood samples will be taken for further analysis.\n\nAt visit 3 the ulcers will be classified as \"non-healing\" if not resolved or not dramatically reduced (more than 50%).",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"medical treatments","All patients will follow the medical treatments, as recommended by the multidisciplinary clinical team (for example revascularization or ulcer debriding) according to the best standard of care",[9,15],[24],{"name":25,"affiliation":5,"role":26},"cecilia Morgantini, MD","PRINCIPAL_INVESTIGATOR",[28],{"name":29,"role":30,"phone":31,"phoneExt":32,"email":33},"Eva Steninger","CONTACT","70 00213 45","0046","eva.steninger@regionstockholm.se",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Karolinska University Hospital","RECRUITING","Huddinge","Stockholm County","141 57","Sweden","SE",{"type":44,"coordinates":45},"Point",[46,47],17.98192,59.23705,{"lat":47,"lon":46},[50],{"name":51,"role":30,"phone":52,"phoneExt":10,"email":53},"Cecilia Morgantini","+46709886692","cecilia.morgantini@ki.se",{"type":26,"investigatorFullName":51,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"MD, PhD","100527988","immune-cells-in-diabetic-chronic-foot-ulcers-100527988",false,"NCT06154915","Immune Cells in Diabetic Chronic Foot Ulcers","Characterise the Immunological Response of Diabetic Patients With Chronic Foot Ulcers","Inclusion Criteria:\n\n* diabetes with diabetic foot ulcer\n\nExclusion Criteria:\n\n* impaired cognitive function\n* on-going immune suppressive treatment\n* diagnosed active cancer\n* cancer treatment\n* known chronic inflammatory disease","ALL","18 Years","98 Years",{"count":67,"type":68},40,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the role of immune cells in patients with diabetes and chronic foot ulcers. Researchers will compare blood and tissue samples of patients with diabetes and a foot ulcer that is healing or healed compared to those diabetic patients where the foot ulcers is not healing (chronic ulcer).",[72,73],"Diabetic Foot","Immune Defect","2025-08-26",{"date":76,"type":77},"2025-09-03","ACTUAL",{"date":79,"type":77},"2022-09-09",{"date":81,"type":68},"2029-12-31",{"name":5,"class":6},1]