[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100455362":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":66,"collaborators":69,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":24,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":24,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":99,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Celiac Disease","EXPERIMENTAL","Individuals with a confirmed diagnosis of celiac disease based on serology and\u002For histology",[13],"Dietary Supplement: Gluten Powder",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Controls","Individuals without a diagnosis of celiac disease",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIETARY_SUPPLEMENT","Gluten Powder","Single oral dose of gluten powder",[9,15],null,[26],{"name":27,"affiliation":5,"role":28},"Jocelyn A Silvester, MD, PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","617-355-8880","jocelyn.silvester@childrens.harvard.edu",{"name":35,"role":31,"phone":24,"phoneExt":24,"email":36},"Marisa Stahl, MD, MSCS","marisa.stahl@childrenscolorado.org",[38,55],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Children's Hospital Colorado","RECRUITING","Aurora","Colorado","80045","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-104.83192,39.72943,{"lat":50,"lon":49},[53],{"name":35,"role":31,"phone":54,"phoneExt":24,"email":36},"720-777-2484",{"facility":5,"status":40,"city":56,"state":57,"zip":58,"country":44,"countryCode":45,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"Boston","Massachusetts","02115",{"type":47,"coordinates":60},[61,62],-71.05977,42.35843,{"lat":62,"lon":61},[65],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},{"type":28,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Jocelyn Silvester","Director of Research, Celiac Disease Program",[70,71],{"name":39,"class":6},{"name":72,"class":73},"Celiac Disease Foundation","UNKNOWN","100455362","immune-responses-to-gluten-100455362",false,"NCT05209568","Immune Responses to Gluten","Changes in Serum IL-2 Levels Following a Single Oral Dose of Gluten","Inclusion Criteria:\n\n1. On a gluten-free diet for ≥ 4 weeks\n2. Willing to consume gluten for research\n3. For the celiac disease arm, diagnosis confirmed by serology and\u002For histology\n\nExclusion Criteria:\n\n1. Pregnancy\n2. Wheat allergy\n3. Type 1 diabetes\n4. BMI z-score \\\u003C -2\n5. History of more than minimal symptoms following gluten exposure on a gluten-free diet\n6. Comorbid condition that in the opinion of the investigator would interfere with study participation or would confound study results",true,"ALL","2 Years","101 Years",{"count":86,"type":87},400,"ESTIMATED","INTERVENTIONAL",[90],"NA","This is a study of immune responses after eating gluten powder in people with celiac disease and healthy controls.",[9,93,94,95,96,97,98],"Malabsorption Syndromes","Digestive System Disease","Intestinal Disease","Gastrointestinal Diseases","Gluten Sensitivity","Celiac Disease in Children",[100,101,102],"gluten","cytokine","T cell immune response","2025-04-18",{"date":105,"type":106},"2025-04-23","ACTUAL",{"date":108,"type":106},"2023-01-15",{"date":110,"type":87},"2029-09-30",{"name":5,"class":6},2]