[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555750":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":40,"locations":50,"responsibleParty":71,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":20,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":20,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":52,"whyStopped":20,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise, Diet, Mindfulness","EXPERIMENTAL","The intervention group will start the intervention immediately following their baseline assessment. They will undergo another assessment after the 6 month intervention period.",[13,14,15],"Behavioral: Exercise","Behavioral: Meditation","Behavioral: Diet",{"label":17,"type":18,"description":19,"interventionNames":20},"Waitlist Group","NO_INTERVENTION","Participants randomized into the waitlist group will undergo a baseline assessment, and will then be encouraged to continue their daily activities as usual for 6 months. Physical activity and sleep will be monitored during this time using wearable devices. Links to questionnaires will be emailed monthly. After the 6-month waitlist period, participants will undergo a second assessment prior to starting the intervention. The multimodal intervention will be 6-months in length, using the same measures of adherence, and will be followed by a final assessment.",null,[22,27,31],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":20},"BEHAVIORAL","Exercise","The intervention will involve online (via University of British Colombia (UBC) Zoom videoconferencing) 1-hour moderate to high intensity exercise classes 3 times a week for 6 months",[9],{"type":23,"name":28,"description":29,"armGroupLabels":30,"otherNames":20},"Meditation","The intervention will involve 15 minute guided mediation following exercise classes as well as mindfulness classes.\n\nMindfulness classes will consist of 1.5 hour Mindfulness Based Stress Reduction (MBSR) classes for the first 2 months, followed by 1 month of 1 hour bi-weekly discussions and practice, then MBSR 2.0 for months 4 and 5, and 1 hour bi-weekly discussions and practice for the remaining month of the intervention.",[9],{"type":23,"name":32,"description":33,"armGroupLabels":34,"otherNames":20},"Diet","The intervention will involve biweekly 1-hour nutrition and cooking classes with a dietician.",[9],[36],{"name":37,"affiliation":38,"role":39},"Silke Appel-Cresswell, MD, FRCPC","University of British Colombia","PRINCIPAL_INVESTIGATOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":20,"email":45},"Jeffrey Kelly, MSc","CONTACT","6048274230","jeffrey.kelly@ubc.ca",{"name":47,"role":43,"phone":48,"phoneExt":20,"email":49},"Annie Kuan","(604) 827-0576","annie.kuan@ubc.ca",[51],{"facility":38,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Vancouver","British Columbia","V6T 1Z3","Canada","CA",{"type":59,"coordinates":60},"Point",[61,62],-123.11934,49.24966,{"lat":62,"lon":61},[65,69,70],{"name":66,"role":43,"phone":67,"phoneExt":20,"email":68},"Madeleine Powell","(604) 822-8691","madeleine.powell@ubc.ca",{"name":47,"role":43,"phone":48,"phoneExt":20,"email":49},{"name":37,"role":39,"phone":20,"phoneExt":20,"email":20},{"type":39,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Silke Cresswell","Principal Investigator",[75],{"name":76,"class":77},"The Jack and Darlene Poole Foundation","UNKNOWN","100555750","impact-360-for-healthy-agers-100555750",false,"NCT06516146","Impact 360 for Healthy Agers","Impact 360 Study for Healthy Agers","Inclusion Criteria:\n\n* Participants who are able to complete questionnaires and follow directions for interventions\n* Have access to a smartphone that can support the Fitbit app\n\nExclusion Criteria:\n\n* Any neurological disease\u002Fdisorder diagnosis (Ex: Parkinson's Disease, Multiple Sclerosis, Traumatic Brain Injury, Brain lesion, Stroke, etc)\n* Any chronic medical condition which would affect ability to participate in exercise\n* Any contraindication for exercise based on the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and medical clearance form\n* Participants who were told by a medical doctor that they need to be medically supervised for exercise\n* Montreal Cognitive Assessment (MoCA) scores \\\u003C21\u002F30\n* Significant cognitive impairment, depression, or eating disorder\n* Any contraindication to MRI scanning; such as implanted metal clips or wires (see list below)\n* Participants currently doing 180 minutes or more of moderate-vigorous intensity exercise per week AND either of the following:\n* Completion of an Mindfulness-Based Stress Reduction course OR; Score \\>8\u002F15 in the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) Diet Questionnaire\n* Significant or unstable cardiovascular or respiratory disease\n* Severe\u002Fmultiple head trauma(s)\n* Subjects who are pregnant or breastfeeding\n* Subjects with a history or major episodes of drug or alcohol abuse\n* Chronic\u002Facute bacterial\u002Fviral infection\n* GI cancer\n* Inflammatory bowel disease\n\nExclusion for MRI scanning:\n\n* Individuals weighing \\> 400 lbs (limit of MRI machine)\n* Artificial heart valve\n* Brain aneurysm clip\n* Electrical stimulator for nerves or bones\n* Ear or eye implant\n* Implanted drug infusion pump\n* Coil, catheter, or filter in any blood vessel\n* Orthopedic hardware (artificial joint, plate, screws)\n* Other metallic prostheses\n* Shrapnel, bullets, or other metal fragments\n* Surgery or tattoos (including tattooed eyeliner) in the last six weeks\n* Brain surgery\n* Have a cardiac pacemaker, wires or defibrillator\n* Have had an injury where a piece of metal lodged in the eye or orbit\n* Have a ferromagnetic aneurysm clip",true,"ALL","50 Years","75 Years",{"count":90,"type":91},60,"ESTIMATED","INTERVENTIONAL",[94],"NA","The Impact 360 study will evaluate the effects of a combined intervention of exercise, mindfulness, and nutrition on 8 key indicators of health and the mechanisms that drive these changes. 60 subjects aged 50 to 75 without a current diagnosis of a brain disorder will be recruited. This study will follow a partial crossover design. All participants will receive the intervention. Participants randomized into the intervention group after their baseline screening will receive the 6-month intervention. Those randomized into the waitlist group will complete another assessment at the end of the 6-month care as usual phase before receiving the intervention.",[97],"Healthy Aging",[24,99,100,101],"Mindfulness","Microbiome","Well-Being","2026-03-19",{"date":104,"type":105},"2026-03-23","ACTUAL",{"date":107,"type":105},"2024-01-24",{"date":109,"type":91},"2028-01-05",{"name":5,"class":6},1]