[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632461":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":41,"centralContacts":50,"locations":58,"responsibleParty":71,"collaborators":31,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":31,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":31,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":31,"overallStatus":95,"whyStopped":31,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"York University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise alone","PLACEBO_COMPARATOR","Exercise Only Group: All procedures in the exercise only treatment will be identical to the exercise and milk\u002Fyogurt groups, except for the dietary component. Participants in the exercise only group will be instructed to maintain their habitual low dairy diets. Nutritional guidance will still be provided to help manage increases in total daily energy expenditure from training.",[13],"Behavioral: Exercise training",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise + Milk","EXPERIMENTAL","Exercise and Milk Group: Participants assigned to the exercise and milk group will begin a 12-week structured exercise program. In addition to exercise training, participants in the exercise and milk group will consume 2 servings of 1% MF milk (1 serving = 250 mL) on non-training days and 3 servings on training days, integrated into their habitual diets. Nutritional guidance from a registered dietitian will be provided to help manage increases in total daily energy expenditure from training, and increased energy intake from milk consumption.",[19,13],"Dietary Supplement: Milk",{"label":21,"type":16,"description":22,"interventionNames":23},"Exercise + Greek Yogurt","Exercise and Greek Yogurt Group: All procedures in the exercise and GY treatment group will be identical to the exercise and milk group, except for what dairy product is consumed. Exercise and GY participants will consume 3 servings of plain or flavoured GY (1 serving = 175 g) on training days, and 2 servings of GY on non-training days.",[24,13],"Dietary Supplement: Greek Yogurt",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Milk","2 servings of 1% MF milk (1 serving = 250 mL) on non-training days and 3 servings on training days, integrated into habitual diet.",[15],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Greek Yogurt","2 servings of plain or flavoured GY (1 serving = 175 g) on non-training days, and 3 servings of GY on training days, integrated into your habitual diet.",[21],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":31},"BEHAVIORAL","Exercise training","12-week structured exercise training program. Exercise sessions will take place three times per week and will last approximately 60 minutes per session. Sessions will be conducted at York University in the Exercise Research Lab. Each session will be facilitated by a certified personal trainer and\u002For kinesiology student",[21,15,9],[42,45,48],{"name":43,"affiliation":5,"role":44},"Nicholas Cheng, MSc","STUDY_DIRECTOR",{"name":46,"affiliation":5,"role":47},"Andrea Josse, PhD","PRINCIPAL_INVESTIGATOR",{"name":49,"affiliation":5,"role":47},"Ali Abdul-Sater, PhD",[51,56],{"name":46,"role":52,"phone":53,"phoneExt":54,"email":55},"CONTACT","416-736-2100","33990","ajosse@yorku.ca",{"name":49,"role":52,"phone":31,"phoneExt":31,"email":57},"aasater@yorku.ca",[59],{"facility":5,"status":31,"city":60,"state":61,"zip":62,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":31},"Toronto","Ontario","M3J 1P3","Canada","CA",{"type":66,"coordinates":67},"Point",[68,69],-79.39864,43.70643,{"lat":69,"lon":68},{"type":47,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Andrea Josse","Associate Professor","100632461","impact-immune-and-musculoskeletal-physiological-adaptations-to-combined-exercise-training--nutrition-100632461",false,"NCT07513987","IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition","Investigating Different Dairy Wholefoods in Combination With Exercise on Inflammation, Immune Cell Function and Musculoskeletal Health in Overweight Adults","Inclusion Criteria:\n\n* Between the ages of 18 and 50 years\n* Overweight BMI (25.0-29.9) kg\u002Fm2\n* 'Overweight' body fat percentage (males: ≤30%; females: ≤42%)\n* Low to moderately physically active (0-2 times\u002Fweek)\n* Habitual low dairy consumption (≤ 1 serving\u002Fday, assessed via baseline food record)\n\nExclusion Criteria:\n\n* Peri- or postmenopausal status (female)\n* Dairy protein allergy or lactose intolerance\n* Use of vitamin D and\u002For calcium supplements\n* Any musculoskeletal, autoimmune, or inflammatory conditions\n* Use of medication related to a chronic condition",true,"ALL","18 Years","50 Years",{"count":86,"type":87},60,"ESTIMATED","INTERVENTIONAL",[90],"NA","The purpose of this study is to determine whether 12 weeks of exercise training combined with dairy consumption influences inflammation and immune responses in adults with overweight, compared to exercise training alone.",[93,94],"Overweight (BMI > 25)","Males and Females","NOT_YET_RECRUITING","2026-04-04",{"date":98,"type":99},"2026-04-07","ACTUAL",{"date":101,"type":87},"2026-05-01",{"date":103,"type":87},"2027-12-31",{"name":5,"class":6},1]