[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100500620":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":41,"centralContacts":45,"locations":55,"responsibleParty":72,"collaborators":10,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":10,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":10,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"ART Fertility Clinics LLC","OTHER",[8,13,16,20,24],{"label":9,"type":10,"description":10,"interventionNames":11},"One CS with isthmocele",null,[12],"Diagnostic Test: Ultrasound between 6+0 and 6+7 weeks of pregnancy - With Isthmocele",{"label":14,"type":10,"description":10,"interventionNames":15},"More than one CS with Isthmocele",[12],{"label":17,"type":10,"description":10,"interventionNames":18},"One or more CS without isthmocele",[19],"Diagnostic Test: Ultrasound between 6+0 and 6+7 weeks of pregnancy - Without Isthmocele",{"label":21,"type":10,"description":10,"interventionNames":22},"With previous vaginal delivery",[23],"Diagnostic Test: Ultrasound between 6+0 and 6+7 weeks of pregnancy",{"label":25,"type":10,"description":10,"interventionNames":26},"With first ongoing pregnancy",[23],[28,33,37],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"DIAGNOSTIC_TEST","Ultrasound between 6+0 and 6+7 weeks of pregnancy - With Isthmocele","Location of implantation of the GS (gestational sac) amended to Naji et al, defined as 3 possible implantation sites: (A: fundal, B: anterior, C: posterior)\n\nSize of isthmocele:\n\n* Depth of isthmocele\n* Width of isthmocele\n* Circumference of isthmocele\n\nDistance between isthmocele and outer cervical os (measured with the trace line) Distance between CS scar and outer cervical os (measured with the trace line) Size of gestational sac Measurements of the isthmocele size \u002F circumference \u002F distance between isthmocele \u002F CS and outer cervical os",[14,9],{"type":29,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Ultrasound between 6+0 and 6+7 weeks of pregnancy - Without Isthmocele","Location of implantation of the GS amended to Naji et al, defined as 3 possible implantation sites: (A: fundal, B: anterior, C: posterior) Distance between CS scar and outer cervical os (measured with the trace line) Size of gestational sac",[17],{"type":29,"name":38,"description":39,"armGroupLabels":40,"otherNames":10},"Ultrasound between 6+0 and 6+7 weeks of pregnancy","Location of implantation of the GS (gestational sac) amended to Naji et al, defined as 3 possible implantation sites (A: fundal, B: anterior, C: posterior)\n\nSize of gestational sac",[25,21],[42],{"name":43,"affiliation":5,"role":44},"Barbara Lawrenz, PhD","PRINCIPAL_INVESTIGATOR",[46,51],{"name":43,"role":47,"phone":48,"phoneExt":49,"email":50},"CONTACT","+971 2 652 8000","1108","barbara.lawrenz@artfertilityclinics.com",{"name":52,"role":47,"phone":48,"phoneExt":53,"email":54},"Jonalyn Edades","1106","jonalyn.edades@artfertilityclinics.com",[56],{"facility":5,"status":57,"city":58,"state":10,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"RECRUITING","Abu Dhabi","60202","United Arab Emirates","AE",{"type":63,"coordinates":64},"Point",[65,66],54.39696,24.45118,{"lat":66,"lon":65},[69,70,71],{"name":43,"role":47,"phone":48,"phoneExt":49,"email":50},{"name":52,"role":47,"phone":48,"phoneExt":53,"email":54},{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},{"type":44,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Barbara Lawrenz","Scientific Director","100500620","impact-of-a-previous-cs-on-the-ongoing-pregnancy-rate-in-single-euploid-frozen-embryo-transfer-et-100500620",false,"NCT05798624","Impact of a Previous CS on the Ongoing Pregnancy Rate in Single Euploid Frozen Embryo Transfer (ET)","To Study the Impact of a Previous Cesarean Section (CS) With \u002F Without an Isthmocele on the Ongoing Pregnancy Rate in Single Euploid Frozen Embryo Transfer","Inclusion Criteria:\n\n\\- All participants undergoing a single euploid FET, independent of the endometrial preparation approach\n\nExclusion Criteria:\n\n* Intracavitary fluid during preparation for FET\n* Known anomaly of the uterus or the adnexae (e.g.: fibroids, polyps, hydrosalpinx, endometriosis, adenomyosis)\n* Embryo which was biopsied on day 7\n* Poor quality embryo which was transferred (Gardner criteria: AC \u002F BC \u002F CB, biopsied on day 6 and CC embryos from both, day 5 and day 6 biopsies, classified as \"poor\" quality embryos)\n* History of recurrent abortion\n* Antiphospholipid syndrome \u002F autoimmune diseases","FEMALE","18 Years","42 Years",{"count":86,"type":87},1050,"ESTIMATED","OBSERVATIONAL","As embryo ploidy is a crucial factor not only for implantation but also for maintenance of a pregnancy, the aim of this study is to evaluate the impact of the CS \u002F isthmocele on the ongoing pregnancy rates and the implantation site in single euploid frozen embryo transfer, independent of the endometrial preparation approach.",[91,92],"Infertility","Implantation",[92,91,94,95],"Isthmocele","Cesarean section","2024-07-16",{"date":98,"type":99},"2024-07-17","ACTUAL",{"date":101,"type":99},"2023-05-01",{"date":103,"type":87},"2025-07-30",{"name":5,"class":6},1]