[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550228":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":117,"collaborators":119,"id":123,"slug":124,"hasResults":125,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":25,"eligibilityCriteria":129,"healthyVolunteers":130,"sex":131,"minAge":132,"maxAge":25,"enrollmentInfo":133,"targetDuration":25,"studyType":136,"phases":137,"briefSummary":139,"conditions":140,"keywords":25,"overallStatus":96,"whyStopped":25,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":151},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Biosynthetic Mesh","EXPERIMENTAL","The biosynthetic mesh group will undergo hiatal hernia repair with Phasix Mesh (Becton Dickinson, Franklin Lakes, NJ) reinforcement, secured with permanent suture. This is a biosynthetic mesh that completely reabsorbs in 12-18 months after surgery. The mesh is designed to provide strength during the initial healing phase after hernia repair, allowing for rapid tissue ingrowth and vascularization, gradually transferring the load to native tissue as it resorbs1. This mesh has been FDA approved for procedures involving soft tissue repair, such as hernia defects.",[13,14],"Device: Biosynthetic Mesh","Procedure: Hiatal Hernia Repair",{"label":16,"type":17,"description":18,"interventionNames":19},"No Mesh","ACTIVE_COMPARATOR","The non-mesh group will undergo repair with permanent suture only.",[14],[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","The biosynthetic mesh group will undergo hiatal hernia repair with Phasix Mesh (Becton Dickinson, Franklin Lakes, NJ) reinforcement, secured with permanent suture.",[9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"PROCEDURE","Hiatal Hernia Repair","The non-mesh group will undergo hiatal hernia repair with permanent suture only.",[9,16],[32],{"name":33,"affiliation":5,"role":34},"Rasa Zarnegar, MD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Annabel Endean, NP","CONTACT","646-962-5250","ant2028@med.cornell.edu",{"name":42,"role":38,"phone":25,"phoneExt":25,"email":43},"Niloufar Salehi, MD","nis4017@med.cornell.edu",[45,59,69,79,94,106],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":25},"University of Southern California Keck School of Medicine","WITHDRAWN","Los Angeles","California","90089","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-118.24368,34.05223,{"lat":57,"lon":56},{"facility":60,"status":47,"city":61,"state":62,"zip":63,"country":51,"countryCode":52,"cosmosGeoPoint":64,"geoPoint":68,"contacts":25},"Louisiana State University School of Medicine","New Orleans","Louisiana","70112",{"type":54,"coordinates":65},[66,67],-90.07507,29.95465,{"lat":67,"lon":66},{"facility":70,"status":47,"city":71,"state":72,"zip":73,"country":51,"countryCode":52,"cosmosGeoPoint":74,"geoPoint":78,"contacts":25},"Washington University School of Medicine","St Louis","Missouri","63110",{"type":54,"coordinates":75},[76,77],-90.19789,38.62727,{"lat":77,"lon":76},{"facility":80,"status":81,"city":82,"state":82,"zip":83,"country":51,"countryCode":52,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"NYU Langone Health","NOT_YET_RECRUITING","New York","10016",{"type":54,"coordinates":85},[86,87],-74.00597,40.71427,{"lat":87,"lon":86},[90,92],{"name":91,"role":38,"phone":25,"phoneExt":25,"email":25},"Luis Espinosa, MD",{"name":93,"role":34,"phone":25,"phoneExt":25,"email":25},"Tanuja Damani, MD",{"facility":95,"status":96,"city":82,"state":82,"zip":97,"country":51,"countryCode":52,"cosmosGeoPoint":98,"geoPoint":100,"contacts":101},"Weill Cornell Medicine","RECRUITING","10065",{"type":54,"coordinates":99},[86,87],{"lat":87,"lon":86},[102,103,105],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},{"name":42,"role":38,"phone":104,"phoneExt":25,"email":43},"212-746-5187",{"name":33,"role":34,"phone":25,"phoneExt":25,"email":25},{"facility":107,"status":81,"city":82,"state":82,"zip":108,"country":51,"countryCode":52,"cosmosGeoPoint":109,"geoPoint":111,"contacts":112},"Lenox Hill Hospital","10075",{"type":54,"coordinates":110},[86,87],{"lat":87,"lon":86},[113,115],{"name":114,"role":38,"phone":25,"phoneExt":25,"email":25},"Mattia Ballo, MD",{"name":116,"role":34,"phone":25,"phoneExt":25,"email":25},"Filippo Filicori, MD",{"type":118,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[120],{"name":121,"class":122},"Intuitive Surgical","INDUSTRY","100550228","impact-of-biosynthetic-mesh-on-paraesophageal-hernia-repair-100550228",false,"NCT06444347","Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair","The Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair in Robotic Anti-Reflux Surgery: A Multi-Institutional Randomized Trial","Inclusion Criteria:\n\n* Documented diagnosis of gastroesophageal reflux disease\n* Adults aged 18 years or older\n* English speaking\n* Subject is planned to undergo surgery for reflux disease\n\nExclusion Criteria:\n\n* Physician deems the subject is unable to complete the study due to documented dementia.\n* Subject is undergoing emergent surgery.\n* Pregnancy\n* Patient has known allergy to tetracycline hydrochloride or kanamycin sulfate",true,"ALL","18 Years",{"count":134,"type":135},200,"ESTIMATED","INTERVENTIONAL",[138],"NA","The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery. Participants undergoing antireflux surgery will be assigned to one of two groups, a group that has surgery with mesh, or a group that has surgery without mesh.",[141],"Hiatal Hernia","2025-11-17",{"date":144,"type":145},"2025-11-18","ACTUAL",{"date":147,"type":145},"2024-06-10",{"date":149,"type":135},"2030-07",{"name":5,"class":6},6]