[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598131":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":25,"responsibleParty":40,"collaborators":43,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":25,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":25,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":25,"overallStatus":67,"whyStopped":25,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":25},{"fullName":5,"class":6},"University of Missouri-Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non Invasive ventilator arm (per current standard of care)","ACTIVE_COMPARATOR","per current standard of care",[13],"Device: Biphasic cuirass ventilator which is a type of negative pressure ventilator will be applied to patients on the intervention arm",{"label":15,"type":16,"description":17,"interventionNames":18},"Biphasic cuirass ventilator arm","EXPERIMENTAL","patients in this arm will be the intervention arm and will be placed on the Biphasic cuirass ventilator.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Biphasic cuirass ventilator which is a type of negative pressure ventilator will be applied to patients on the intervention arm","As opposed to patients being placed on Non invasive ventilation (CPAP or BiPAP) the intervention arm patients will be placed on the Biphasic cuirass ventilator which is a form of negative pressure ventilator.",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Dennis B Chairman, MD","T","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":35},"CONTACT","573 884 1057","chairmand@umsystem.edu",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Tamar Gubeladze, MD","573 884 0808","gubeladzet@health.missouri.edu",{"type":30,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Dennis Chairman","Associate Professor",[44],{"name":45,"class":46},"Hayek Medical","UNKNOWN","100598131","impact-of-biphasic-cuirass-ventilation-compared-to-non-invasive-ventilation-in-high-risk-extubations-100598131",false,"NCT07067502","Impact of Biphasic Cuirass Ventilation Compared to Non Invasive Ventilation in High Risk Extubations","Impact of Biphasic Cuirass Ventilation Compared to Non-Invasive Ventilation in High Risk Extubations","Inclusion Criteria:\n\n* High risk extubation patients in the Medical Intensive care units who are being thought to be placed on non invasive ventilator post extubation.\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>80\n* Pregnant\n* Inmate\u002FPrisoner\n* Chest wall defects\n* BMI \\>50\n* History of Diaphragmatic paralysis\n* History of Neuromuscular disease\n* Contraindication to study device (open chest wound, flail chest, complex thoracic surgeries in the past)","ALL","19 Years","80 Years",{"count":58,"type":59},50,"ESTIMATED","INTERVENTIONAL",[62],"NA","subjects on mechanical ventilator who are about to be extubated to Non invasive ventilation because the physician thinks they are high risk for failure will be approached and consented for our study. Once randomized they will either be on the standard of care Non invasive arm or the intervention arm which would mean they are placed on the Biphasic cuirass ventilation.",[65,66],"Respiratory Failure","Extubation Failure","NOT_YET_RECRUITING","2026-02-10",{"date":70,"type":71},"2026-02-13","ACTUAL",{"date":73,"type":59},"2026-03-01",{"date":75,"type":59},"2026-10-30",{"name":5,"class":6}]