[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541912":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Simon Fraser University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Image and video data set shown with BII stimuli.","EXPERIMENTAL","Participants will undergo this test on two separate days. On each day, participants will be asked to watch a series of videos and images. For this arm of the study, participants will view the BII phobia-related stimuli.",[13],"Other: blood-injection-injury (BII) phobia stimuli",{"label":15,"type":16,"description":17,"interventionNames":18},"Image and video data set shown with neutral stimuli.","PLACEBO_COMPARATOR","Participants will undergo this test on two separate days. On each day, participants will be asked to watch a series of videos and images. For this arm of the study, participants will view the neutral stimuli.",[19],"Other: neutral stimuli",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"blood-injection-injury (BII) phobia stimuli","498 seconds of BII phobia-related images and videos will begin two-minutes prior to head-up tilt test, while in supine.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"neutral stimuli","498 seconds of neutral images and videos will begin two-minutes prior to head-up tilt test, while in supine.",[15],[31],{"name":32,"affiliation":33,"role":34},"Victoria E Claydon, PhD","Professor, Biomedical Physiology and Kinesiology","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","7787828513","victoria_claydon@sfu.ca",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Vera E Lucci, PhD","7787828560","vlucci@sfu.ca",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Burnaby","British Columbia","V5A 1S6","Canada","CA",{"type":53,"coordinates":54},"Point",[55,56],-122.95263,49.26636,{"lat":56,"lon":55},[59,60],{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},{"name":32,"role":34,"phone":25,"phoneExt":25,"email":25},{"type":34,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Dr. Victoria Claydon","Professor","100541912","impact-of-blood-phobia-on-fainting-susceptibility-100541912",false,"NCT06336031","Impact of Blood Phobia on Fainting Susceptibility","Inclusion Criteria:\n\n* male and female\n* 18 to 50 years old\n* those without a suspected BII fear and those with a suspected fear\n* english speaking\n\nExclusion Criteria:\n\n* diagnosis of any cardiovacular or neurological disorder\n* menopausal\n* taking medication for a cardiovascular condition\n* if they are pregnant",true,"ALL","18 Years","50 Years",{"count":75,"type":76},20,"ESTIMATED","INTERVENTIONAL",[79],"NA","The primary purpose of this study is to characterize cardiovascular autonomic function to emotional stimuli (blood-injection-injury phobia \\[needle phobia\\]) during an orthostatic (upright) challenge in individuals with and without known needle phobia. It is well established that emotional stress can produce hypotensive (low blood pressure) reactions. Interestingly, these hypotensive reactions to venipuncture (even with minimal blood drawn), insulin injections, finger sticks for blood sugar monitoring, dental care, and vaccinations can affect up to a quarter of adults and appear to be uniquely associated with blood-injection-injury phobia rather than other phobias. These hypotensive reactions can ultimately lead to a vasovagal syncope (fainting) response, and lead to increased avoidance of medical and dental procedures as a result of this phobia. Ultimately, this has severe implications on public health and places additional strain on the Canadian healthcare system. Currently, there is limited understanding surrounding the initiation of this response. Additionally, a comprehensive profile of cardiovascular autonomic function during exposure to provoking stimuli during orthostatic stress has not been captured in the literature. We will test individuals with and without blood-injection-injury phobia using our standard approach while exposing them to emotional stimuli.",[82,83],"Syncope, Vasovagal","Blood, Injection, Injury Type Phobia",[85],"tilt table","2025-05-12",{"date":88,"type":89},"2025-05-15","ACTUAL",{"date":91,"type":89},"2024-03-30",{"date":93,"type":76},"2026-12",{"name":5,"class":6},1]