[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100438790":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":40,"centralContacts":45,"locations":51,"responsibleParty":68,"collaborators":70,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":10,"eligibilityCriteria":82,"healthyVolunteers":79,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":10,"studyType":89,"phases":10,"briefSummary":90,"conditions":91,"keywords":10,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,16,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Male Cancer Survivors with DVSS Score ≥ 9",null,"Childhood cancer survivors treated with DOX and\u002For VCR with evidence of BD on DVSS",[13,14,15],"Diagnostic Test: Non-invasive Urodynamic Test (niUDS)","Diagnostic Test: Urinary proteomic screen","Other: Dysfunctional Voiding Symptom Score Survey (DVSS)",{"label":17,"type":10,"description":11,"interventionNames":18},"Female Cancer Survivors with DVSS Score ≥ 6",[13,14,15],{"label":20,"type":10,"description":21,"interventionNames":22},"Male Cancer Survivors with DVSS Score \u003C 9","Childhood cancer survivors treated with DOX and\u002For VCR without evidence of BD on DVSS",[13,14,15],{"label":24,"type":10,"description":21,"interventionNames":25},"Female Cancer Survivors with DVSS Score \u003C 6",[13,14,15],[27,32,36],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"DIAGNOSTIC_TEST","Non-invasive Urodynamic Test (niUDS)","A noninvasive urodynamics is a simple test used to evaluate urinary flow.",[24,17,20,9],{"type":28,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"Urinary proteomic screen","Urine proteomics is a powerful platform to identify urinary excreted proteins and peptides in different stages of disease or therapy and to determine their quantity, functions, and interaction.",[24,17,20,9],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"Dysfunctional Voiding Symptom Score Survey (DVSS)","The Dysfunctional Voiding Symptom Score provides accurate and objective grading of voiding behaviors of children.",[24,17,20,9],[41],{"name":42,"affiliation":43,"role":44},"Nicholas Cost, MD","Children's Hospital Colorado","PRINCIPAL_INVESTIGATOR",[46],{"name":47,"role":48,"phone":49,"phoneExt":10,"email":50},"Gemma Beltran","CONTACT","(720) 777-4418","gemma.beltran@childrenscolorado.org",[52],{"facility":43,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"RECRUITING","Aurora","Colorado","80045","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-104.83192,39.72943,{"lat":63,"lon":62},[66,67],{"name":47,"role":48,"phone":49,"phoneExt":10,"email":50},{"name":42,"role":44,"phone":10,"phoneExt":10,"email":10},{"type":69,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[71,74,76],{"name":72,"class":73},"National Cancer Institute (NCI)","NIH",{"name":75,"class":73},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",{"name":43,"class":6},"100438790","impact-of-chemotherapy-on-urinary-biomarkers-and-non-invasive-urodynamics-in-children-100438790",false,"NCT04993859","Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children","Inclusion Criteria:\n\n* Children aged 5-13 years old\n* A history of cancer\n* Treatment with a chemotherapy regimen including VCR and\u002For DOX\n* Completion of chemotherapy at least one year prior to study enrollment and survey completion.\n\nExclusion Criteria:\n\n* Patients with a:\n* Primary pelvic tumor\n* Pelvic irradiation\n* Pre-existing bladder\u002Fbowel dysfunction\n* Spinal defects\n* Neurologic disorder\n* Neuro-oncologic tumor or brain metastasis\n* Cyclophosphamide or ifosfamide therapy","ALL","5 Years","13 Years",{"count":87,"type":88},152,"ESTIMATED","OBSERVATIONAL","The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.",[92,93],"Survivors of Childhood Cancer","Bladder Dysfunction","2025-10-13",{"date":96,"type":97},"2025-10-15","ACTUAL",{"date":99,"type":97},"2021-06-02",{"date":101,"type":88},"2026-07-09",{"name":5,"class":6},1]