[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619592":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":19,"collaborators":10,"id":23,"slug":24,"hasResults":25,"nctId":26,"briefTitle":27,"officialTitle":28,"acronym":10,"eligibilityCriteria":29,"healthyVolunteers":25,"sex":30,"minAge":31,"maxAge":10,"enrollmentInfo":32,"targetDuration":35,"studyType":36,"phases":10,"briefSummary":37,"conditions":38,"keywords":10,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":10},{"fullName":5,"class":6},"Sohag University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"adult bronchiectasis patient with acute excerbations",null,"Group 1: Mild-to-Moderate Disease Severity Patients diagnosed with bronchiectasis who present with acute exacerbations and have mild to moderate disease severity scores (based on BSI or FACED scoring). Data on comorbidities, clinical outcomes, and hospital stay will be recorded.\n\nGroup 2: Severe Disease Severity Patients with acute exacerbations of bronchiectasis classified as severe according to BSI or FACED score. These patients are expected to have higher comorbidity burden and worse clinical outcomes.\n\nAlternative grouping (if by comorbidity burden):\n\nGroup A: With Significant Comorbidities Patients with one or more major comorbidities such as COPD, diabetes, or cardiovascular disease.\n\nGroup B: Without Significant Comorbidities Patients without major comorbid conditions, serving as a comparison group.",[13],"Other: Observational assessment of comorbidities and disease severity",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Observational assessment of comorbidities and disease severity","\\> This study involves no active intervention. Data will be collected from patients with acute exacerbations of bronchiectasis to assess the impact of comorbidities and disease severity on clinical outcomes such as hospital stay, ICU admission, and mortality.",[9],{"type":20,"investigatorFullName":21,"investigatorTitle":22,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Aliaa Elsayed Mahmoud","Impact of comorbiditries and Disease severity on clinical outcomes of patients with acute exacerbations of bronchiectesis","100619592","impact-of-comorbidities-and-severity-on-outcomes-in-bronchiectasis-excerbations-100619592",false,"NCT07346625","Impact of Comorbidities and Severity on Outcomes in Bronchiectasis Excerbations","Impact of Comorbiditries and Disease Severity on Clinical Outcomes of Patients With Acute Exacerbations of Bronchiectesis","Inclusion Criteria:\n\n* Adults (≥18 years) admitted with a diagnosis of \"Bronchiectasis with acute exacerbation\". The bronchiectasis exacerbation is diagnosed based on deterioration in three or more of the following main symptoms for 48h at least: cough, sputum volume or sputum consistency, purulent sputum, breathlessness or exercise tolerance, fatigue or malaise, hemoptysis, and the requirement of a change in the bronchiectasis treatment as determined by a clinician.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age. Patients who refuse participation or whose medical records lack informed consent (if applicable).","ALL","18 Years",{"count":33,"type":34},100,"ESTIMATED","1 Year","OBSERVATIONAL","Acute exacerbations of bronchiectasis are associated with variable outcomes depending on patient factors. Comorbidities such as COPD, diabetes, and cardiovascular disease, as well as disease severity scores, significantly influence hospitalization rates, length of stay, need for intensive care, and mortality. Understanding these associations helps in risk stratification, guiding management, and improving prognosis in affected patients.",[39],"Bronchiectasis With Acute Exacerbation","NOT_YET_RECRUITING","2026-01-07",{"date":43,"type":44},"2026-01-16","ACTUAL",{"date":46,"type":34},"2026-02-01",{"date":48,"type":34},"2026-12-01",{"name":5,"class":6}]