[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613024":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":50,"collaborators":23,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":23,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":23,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":36,"whyStopped":23,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Ottawa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exposure to indoor temperature upper limit of 26°C","EXPERIMENTAL","Participants exposed daylong (6 hours) to an indoor temperature maintained at 26°C and 45% relative humidity (humidex equivalent of 29).",[13],"Other: Simulated exposure to indoor overheating",{"label":15,"type":10,"description":16,"interventionNames":17},"Exposure to hot indoor environment of 36°C","Participants exposed daylong (6 hours) to an indoor temperature maintained at 36°C and 45% relative humidity (humidex equivalent of 45).",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Simulated exposure to indoor overheating","Children exposed to a 6-hour simulated heat exposure",[15,9],null,[25],{"name":26,"affiliation":5,"role":27},"Glen P Kenny, PhD","PRINCIPAL_INVESTIGATOR",[29],{"name":26,"role":30,"phone":31,"phoneExt":32,"email":33},"CONTACT","613-562-5800","4282","gkenny@uottawa.ca",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Ottawa","Ontario","K1N 6N5","Canada","CA",{"type":43,"coordinates":44},"Point",[45,46],-75.69812,45.41117,{"lat":46,"lon":45},[49],{"name":26,"role":30,"phone":31,"phoneExt":32,"email":33},{"type":27,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Glen P. Kenny","Full Professor, University Research Chair","100613024","impact-of-indoor-overheating-on-physiological-strain-in-children-100613024",false,"NCT07261202","Impact of Indoor Overheating on Physiological Strain in Children","A Preliminary Study Assessing the Effectiveness of a 26 °C Indoor Temperature Limit on Physiological Responses in Children","Inclusion Criteria:\n\n* English or French speaking.\n* Ability to provide informed assent.\n\nExclusion Criteria:\n\n* Chronic health conditions\n* Endurance exercise training (greater than 3 sessions of vigorous exercise training per week for 30 minutes or more)\n* Restrictions to physical activity",true,"ALL","10 Years","15 Years",{"count":65,"type":66},10,"ESTIMATED","INTERVENTIONAL",[69],"NA","Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children. Compared with adults, children are more susceptible to heat related illness due to less efficient thermoregulatory systems and difficulty recognizing early signs of heat stress. In addition, prolonged heat exposure can adversely affect their mental health, contributing to cognitive decline, heightened anxiety, and irritability. As children spend substantial time in hot environments at school and at home, and as these conditions intensify with climate change, actions to safeguard their health are essential. Yet our understanding of heat exposure effects in children remains incomplete, hindering the development of evidence based strategies to protect them.\n\nTo address this gap, the investigators aim to evaluate whether an indoor temperature limit of 26 °C (45 percent relative humidity), the upper threshold recommended to protect older adults, can effectively prevent dangerous increases in physiological strain and declines in cognitive function in children during a simulated daylong heatwave. The preliminary study will assess physiological and cognitive responses in children aged 10 to 15 years during a 6 hour exposure (approximating a typical school day) to two conditions: (1) the recommended indoor temperature upper limit (26 °C) and (2) a high heat condition representative of homes and schools without air conditioning during extreme heat events (36 °C). In both conditions, children will remain seated at rest while wearing light clothing (t shirt and shorts), with the exception of performing 15 minutes of stepping exercise (6-6.5 METS) each hour (excluding the lunch period) to reflect typical daily activity in a school setting. This experimental design will allow investigators to determine whether maintaining indoor temperatures at the recommended upper limit for older adults sufficiently mitigates physiological strain in children.",[72,73,74],"Heat Stress","Physiological Stress","Cognitive Change",[76,77,78,79,80,81,82,83,84,85,86],"Indoor overheating","Indoor temperatures","Heat wave","Thermoregulation","Adolescent","Heat strain","Heat vulnerability","Hyperthermia","Youth","Thermal comfort","Physical activity","2026-04-20",{"date":89,"type":90},"2026-04-23","ACTUAL",{"date":92,"type":90},"2025-11-08",{"date":94,"type":66},"2026-12-31",{"name":5,"class":6},1]