[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546800":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":51,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Vrinnevi Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective cohort",null,"Prospective cohort measuring the previously described biomarkers.",[13],"Other: Blood sampling",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"Blood sampling",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Jakob Hytting, MD","CONTACT","+46 + 707679724","jakob.hytting@liu.se",[25,40],{"facility":26,"status":27,"city":28,"state":29,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Medical department","RECRUITING","Jönköping","Småland","Sweden","SE",{"type":33,"coordinates":34},"Point",[35,36],14.15618,57.78145,{"lat":36,"lon":35},[39],{"name":20,"role":21,"phone":10,"phoneExt":10,"email":23},{"facility":41,"status":27,"city":42,"state":43,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":44,"geoPoint":48,"contacts":49},"Cardiology Clinic","Norrköping","Östergötland County",{"type":33,"coordinates":45},[46,47],16.1826,58.59419,{"lat":47,"lon":46},[50],{"name":20,"role":21,"phone":10,"phoneExt":10,"email":23},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jakob Hytting","MD, Department of Cardiology, Principal Investigator, Doctoral Candidate",[56],{"name":57,"class":6},"Ryhov County Hospital","100546800","impact-of-inflammatory-indexes-and-gene-scores-in-prediction-of-atrial-fibrillation-100546800",false,"NCT06399666","Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation","Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation - IERV Trial","IERV","Inclusion Criteria:\n\n* Persistent atrial fibrillation (ICD-10 I48.1)\n* Age over 18 years\n\nExclusion Criteria:\n\n* Autoimmune disease\n* Inflammatory diseases\n* Acute or chronic liver dysfunction\n* Ongoing infectious diseases\n* Thyroid disorders\n* Any other conditions known to impact inflammatory activity (including medication use and hematological diseases)",true,"ALL","18 Years",{"count":70,"type":71},182,"ESTIMATED","OBSERVATIONAL","Because of the high recurrence rates following electrical cardioversion and high morbidity in AF patients there is a need to explore prediction models for AF recurrence following ECV. Previous studies have primarily focused on high-sensitivity CRP (hsCRP), CRP, and IL-6, while other inflammatory indexes and gene scores might hold greater value.\n\nThis prospective cohort study is planning to include 182 patients with persistent atrial fibrillation, planned for electrical cardioversion, and \\>18 years at two medium-sized hospitals in Sweden. Blood samples will be collected prior to electrical cardioversion and at 7-, 30-, 90-, and 180-days follow-up. Atrial fibrillation recurrence will be evaluated at follow-up or upon patient request and diagnosed with 12-lead ECG.\n\nAn interim analysis will be conducted after more than 80 patients have been included. If the results from univariate and\u002For multivariable logistic regression on inflammatory markers and genetic expression regarding atrial fibrillation recurrence are significant, the study will be concluded.",[75,76,77],"Atrial Fibrillation","Inflammation","Genetic Predisposition to Disease","2024-09-11",{"date":80,"type":81},"2024-09-19","ACTUAL",{"date":83,"type":81},"2023-10-30",{"date":85,"type":71},"2026-02-28",{"name":5,"class":6},2]