[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577910":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":19,"centralContacts":39,"locations":45,"responsibleParty":63,"collaborators":19,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":19,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":19,"enrollmentInfo":75,"targetDuration":19,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":19,"overallStatus":48,"whyStopped":19,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Iuliu Hatieganu University of Medicine and Pharmacy","OTHER",[8,15,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"+ NOL + lidocaine group","EXPERIMENTAL","NOL guided analgesia and intravenous lidocaine infusion",[13,14],"Drug: Lidocaine Intravenous Infusion","Device: NOL",{"label":16,"type":17,"description":18,"interventionNames":19},"- NOL - lidocaine group","NO_INTERVENTION","group without NOL monitoring or lidocaine administration",null,{"label":21,"type":10,"description":22,"interventionNames":23},"+ NOL - lidocaine group","NOL guided analgesia without intravenous lidocaine infusion",[14],{"label":25,"type":10,"description":26,"interventionNames":27},"- NOL + lidocaine group","group without NOL monitoring but with lidocaine intravenous infusion",[13],[29,34],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":19},"DRUG","Lidocaine Intravenous Infusion","intravenous lidocaine 10 mg\u002Fml continuous infusion",[9,25],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":19},"DEVICE","NOL","Intraoperative Nociception Level index monitoring and guided analgesia",[9,21],[40],{"name":41,"role":42,"phone":43,"phoneExt":19,"email":44},"Cristiana Osoian","CONTACT","+40743352189","osoiancris@yahoo.com",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":19,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Regional Gastroenterology and Hepatology Institute Octavian Fodor","RECRUITING","Cluj-Napoca","Cluj","Romania","RO",{"type":54,"coordinates":55},"Point",[56,57],23.6,46.76667,{"lat":57,"lon":56},[60,61],{"name":41,"role":42,"phone":43,"phoneExt":19,"email":44},{"name":41,"role":62,"phone":19,"phoneExt":19,"email":19},"PRINCIPAL_INVESTIGATOR",{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Osoian Cristiana","Principal Investigator","100577910","impact-of-intraoperative-non-invasive-analgesia-monitoring-using-nociception-level-index-on-patient-management-100577910",false,"NCT06804434","Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management","Inclusion Criteria:\n\n* age \\> 18 years\n* ASA score I-III\n* surgery for gastric or hepatobiliary or pancreatic neoplasia\n\nExclusion Criteria:\n\n* pregnancy\n* lactation\n* neuraxial or regional anesthesia\n* chronic treatment with drugs that can influence autonomic nervous system\n* diuretics or nitroglycerin administration on the day of surgery\n* severe neurological disability\n* severe hemodynamic instability\n* chronic pain\n* chronic opioid treatment\n* allergy to any of the study drugs\n* severe untreated disease or organ failure\n* pacemaker\n* emergency surgery\n* patient refusal to participate","ALL","18 Years",{"count":76,"type":77},160,"ESTIMATED","INTERVENTIONAL",[80],"NA","This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.",[83,84,85],"Pain","Anesthesia","Perioperative Care","2025-01-27",{"date":88,"type":89},"2025-02-03","ACTUAL",{"date":91,"type":89},"2023-05-18",{"date":93,"type":77},"2026-02-01",{"name":65,"class":6},1]