[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604699":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":60,"collaborators":24,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":24,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":24,"overallStatus":36,"whyStopped":24,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group Iso","EXPERIMENTAL","Patients will receive general anesthesia and maintenance by isoflurane.",[13],"Drug: Isoflurane",{"label":15,"type":10,"description":16,"interventionNames":17},"Group Sev","Patients will receive general anesthesia and maintenance by sevoflurane.",[18],"Drug: Sevoflurane",[20,25],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG","Isoflurane",[9],null,{"type":21,"name":26,"description":16,"armGroupLabels":27,"otherNames":24},"Sevoflurane",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Eman A Ali, Master","CONTACT","00201008005684","eman.adel@med.asu.edu.eg",[35],{"facility":5,"status":36,"city":37,"state":24,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Cairo","11591","Egypt","EG",{"type":42,"coordinates":43},"Point",[44,45],31.24967,30.06263,{"lat":45,"lon":44},[48,49,52,54,56,58],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},{"name":50,"role":51,"phone":24,"phoneExt":24,"email":24},"Ayman M Kamaly, MD","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":24,"phoneExt":24,"email":24},"Randa A Shoukry, MD",{"name":55,"role":51,"phone":24,"phoneExt":24,"email":24},"Tarek S Shabana, MD",{"name":57,"role":51,"phone":24,"phoneExt":24,"email":24},"Abdelrahman M Elsotouhy, MD",{"name":59,"role":51,"phone":24,"phoneExt":24,"email":24},"Haitham K Sultan, MD",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Eman adel ali abd moaty","Assistant Lecturer of Anesthesiology, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University.","100604699","impact-of-isoflurane-and-sevoflurane-on-oxidative-stress-in-patients-undergoing-laparoscopic-cholecystectomy-100604699",false,"NCT07152912","Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy","A Comparative Study Between the Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* Age from 20 to 60 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) Physical Status I-II.\n* Undergoing elective laparoscopic cholecystectomy under general anesthesia.\n\nExclusion Criteria:\n\n* Refusal of participation in the study by patients.\n* Diabetes (type I or II), endocrine system, and immune system diseases.\n* Chronic infection and sepsis.\n* Cardiac condition as classified bythe New York Heart Association (NYHA) \\> class II.\n* Hepatic disease: INR \\> 1.5, and\u002For albumin \\\u003C 2.5 g\u002FdL.\n* Renal disease: glomerular filtration rate (GFR) \\\u003C 85 ml\u002Fmin.\n* Mental and neurological disorders.","ALL","20 Years","60 Years",{"count":75,"type":76},80,"ESTIMATED","INTERVENTIONAL",[79],"NA","The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive surgery (laparoscopic cholecystectomy).",[22,26,82,83],"Oxidative Stress","Laparoscopic Cholecystectomy","2025-09-04",{"date":86,"type":87},"2025-09-05","ACTUAL",{"date":84,"type":87},{"date":90,"type":76},"2026-03-01",{"name":5,"class":6},1]