[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545529":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":61,"centralContacts":65,"locations":74,"responsibleParty":118,"collaborators":32,"id":120,"slug":121,"hasResults":122,"nctId":123,"briefTitle":124,"officialTitle":124,"acronym":125,"eligibilityCriteria":126,"healthyVolunteers":122,"sex":127,"minAge":128,"maxAge":32,"enrollmentInfo":129,"targetDuration":32,"studyType":132,"phases":133,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":77,"whyStopped":32,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":152},{"fullName":5,"class":6},"Johns Hopkins University","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Neck Manual, Stretches, Pain Neuroscience Education with Voice Exercise and Scar Massage Arm","ACTIVE_COMPARATOR","Patients will receive direct manual massage to the anterior neck, general neck stretches and pain neuroscience education along with voice exercises and scar massage with a trained Speech-Language Pathologist",[13,14,15,16,17],"Behavioral: Anterior Neck Manual Therapy","Behavioral: Pain Neuroscience Education","Behavioral: Neck Stretches","Behavioral: Scar massage","Behavioral: Voice Exercises",{"label":19,"type":20,"description":21,"interventionNames":22},"Voice Exercises and Scar Massage with placebo Manual\u002FStretching and Pain Education","PLACEBO_COMPARATOR","Patients will be given voice exercise and scar massages with a trained Speech Language Pathologist, alongside placebo manual\u002Fstretching and placebo pain education.",[16,17,23,24,25],"Behavioral: Placebo Anterior Neck Manual Therapy","Behavioral: Placebo Pain Neuroscience Education","Behavioral: Placebo Neck Stretches",[27,33,37,41,45,49,53,57],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Anterior Neck Manual Therapy","Manual massage applied to the anterior neck, including hyolaryngeal elevators, depressors, sternocleidomastoid.",[9],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Pain Neuroscience Education","Description of how the pain system works from a neurobiological level, discussing the biopsychosocial model that influences pain.",[9],{"type":28,"name":38,"description":39,"armGroupLabels":40,"otherNames":32},"Neck Stretches","Bilateral cervical side bending, cervical extension and bilateral rotational neck stretches held for 20 seconds x3.",[9],{"type":28,"name":42,"description":43,"armGroupLabels":44,"otherNames":32},"Scar massage","Digital manipulation of the scar itself in circles.",[9,19],{"type":28,"name":46,"description":47,"armGroupLabels":48,"otherNames":32},"Voice Exercises","Stemple Voice Exercises",[9,19],{"type":28,"name":50,"description":51,"armGroupLabels":52,"otherNames":32},"Placebo Anterior Neck Manual Therapy","Will apply extremely light manual contact to the anterior neck, including hyolaryngeal elevators, depressors, sternocleidomastoid.",[19],{"type":28,"name":54,"description":55,"armGroupLabels":56,"otherNames":32},"Placebo Pain Neuroscience Education","Will discuss how pain will as a result of the surgical intervention.",[19],{"type":28,"name":58,"description":59,"armGroupLabels":60,"otherNames":32},"Placebo Neck Stretches","Will ask patient to look down as a neck stretch held for 20 seconds x3.",[19],[62],{"name":63,"affiliation":5,"role":64},"Vaninder Dhillon, MD","PRINCIPAL_INVESTIGATOR",[66,71],{"name":67,"role":68,"phone":69,"phoneExt":32,"email":70},"Claire W Ligon, M.Ed.","CONTACT","434-390-6387","Cligon4@jhmi.edu",{"name":63,"role":68,"phone":72,"phoneExt":32,"email":73},"925-360-5939","vdhillo2@jhmi.edu",[75,102],{"facility":76,"status":77,"city":78,"state":79,"zip":80,"country":81,"countryCode":82,"cosmosGeoPoint":83,"geoPoint":88,"contacts":89},"Johns Hopkins Hospital","RECRUITING","Baltimore","Maryland","21287","United States","US",{"type":84,"coordinates":85},"Point",[86,87],-76.61219,39.29038,{"lat":87,"lon":86},[90,93,97,99,100],{"name":91,"role":68,"phone":69,"phoneExt":32,"email":92},"Claire Ligon, Masters of Education","cligon4@jhmi.edu",{"name":94,"role":68,"phone":95,"phoneExt":32,"email":96},"Kristine Pietsch, Masters of Arts","518-461-3610","kteets1@jhmi.edu",{"name":91,"role":98,"phone":32,"phoneExt":32,"email":32},"SUB_INVESTIGATOR",{"name":94,"role":98,"phone":32,"phoneExt":32,"email":32},{"name":101,"role":98,"phone":32,"phoneExt":32,"email":32},"Michelle Wilson, Masters of Science",{"facility":103,"status":77,"city":104,"state":79,"zip":105,"country":81,"countryCode":82,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Suburban Hospital","Bethesda","20817",{"type":84,"coordinates":107},[108,109],-77.10026,38.98067,{"lat":109,"lon":108},[112,113,115,116,117],{"name":91,"role":68,"phone":69,"phoneExt":32,"email":92},{"name":114,"role":68,"phone":72,"phoneExt":32,"email":73},"Vaninder Dhillon, Medical Doctor",{"name":114,"role":64,"phone":32,"phoneExt":32,"email":32},{"name":91,"role":98,"phone":32,"phoneExt":32,"email":32},{"name":101,"role":98,"phone":32,"phoneExt":32,"email":32},{"type":119,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100545529","impact-of-manual-therapy-on-laryngeal-function-following-total-thyroidectomy-100545529",false,"NCT06383091","Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy","Man Total Thy","Inclusion Criteria:\n\n* The study population consists of individuals with malignant or benign thyroid disease scheduled to undergo total thyroidectomy\n* native speakers of English\n* All patients will be greater than or equal to 18 years of age\n\nExclusion Criteria:\n\n* Participants will be excluded if they have completed voice therapy prior\n* are current smokers\n* have organic vocal fold pathology or clear mucosal changes to the vocal folds that can affect vibration (e.g., vocal fold scar, polyp, or nodules),\n* pre-existing unilateral or bilateral vocal fold paralysis\n* have had prior surgical neck or chest history including central or lateral neck dissection\n* pre- or post-operative abscess or inflammation\n* have a history of head, neck, or chest radiation, diagnosed baseline oral or pharyngeal dysphagia\n* have recently started taking in the last 3 months, plan to start taking or increase the level of testosterone during the treatment period\n* greater than 10% otherwise unexplained weight loss\n* had a recent aspiration pneumonia","ALL","18 Years",{"count":130,"type":131},20,"ESTIMATED","INTERVENTIONAL",[134],"NA","In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage will effectively treatment patient complaints of swallowing or voice changes after total thyroidectomy as compared to voice exercise and scar massage alone.\n\nThe main questions it aims to answer are:\n\nWill neck massage, stretches and pain science education reduce patient complaints of swallowing changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education reduce patient complaints of voice changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education reduce patient complaints of scar tethering and quality changes after total thyroidectomy?\n\nWill neck massage, stretches and pain science education improve quality of life after total thyroidectomy?\n\nParticipants will:\n\nParticipate in 4 visits with the participant's endocrine\u002Flaryngology surgeon. One prior and 3 after surgery for endoscopic evaluation and tests.\n\nParticipate in 5 Speech-Language Pathology Sessions for intervention exercises and tests. One prior and 4 after surgery.\n\nComplete a journal of the participant's Home Exercise Practice",[137],"Total Thyroidectomy",[139,140,141,142],"manual","pain neuroscience education","total thyroidectomy","Speech Pathology","2026-06-17",{"date":145,"type":146},"2026-06-22","ACTUAL",{"date":148,"type":146},"2024-06-03",{"date":150,"type":131},"2027-12",{"name":5,"class":6},2]