[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568305":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":43,"centralContacts":50,"locations":60,"responsibleParty":77,"collaborators":81,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":93,"sex":94,"minAge":95,"maxAge":34,"enrollmentInfo":96,"targetDuration":34,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":113,"overallStatus":63,"whyStopped":34,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Universite de La Reunion","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"N-PF (Natural Cycle - Follicular Phase-Intensified Training)","EXPERIMENTAL","Female athletes with natural menstrual cycles who follow a resistance training program with increased intensity during the follicular phase and reduced intensity during the luteal phase. This arm aims to evaluate the impact of follicular-phase-focused training on neuromuscular performance, leveraging the potential effects of elevated estrogen levels during this phase.\n\nIntervention:\n\nResistance Training Program: 13 weeks, 2 sessions per week, with higher intensity training scheduled during the follicular phase (early and late) and reduced intensity during the luteal phase.",[13],"Other: Resistance periodized training program (N-PF)",{"label":15,"type":10,"description":16,"interventionNames":17},"N-PL (Natural Cycle - Luteal Phase-Intensified Training)","Description: Female athletes with natural menstrual cycles who undergo a resistance training program with increased intensity during the luteal phase and reduced intensity during the follicular phase. This approach assesses the impact of training when progesterone levels are elevated.\n\nIntervention:\n\nResistance Training Program: 13 weeks, 2 sessions per week, with higher intensity training during the luteal phase (early and late) and reduced intensity during the follicular phase.",[18],"Other: Resistance peioridized training program (N-PL)",{"label":20,"type":10,"description":21,"interventionNames":22},"N-C (Natural Cycle - Continuous Training)","Description: Female athletes with natural menstrual cycles who participate in a continuous intensity training program across all phases of the menstrual cycle. This group provides a comparison to determine the effects of a non-phase-specific training protocol on neuromuscular function.\n\nIntervention:\n\nResistance Training Program: 13 weeks, 2 sessions per week, maintaining a consistent training intensity across both follicular and luteal phases.",[23],"Other: Continuous resistance training program (C)",{"label":25,"type":26,"description":27,"interventionNames":28},"OCP-C (Oral Contraceptive - Continuous Training, Control Group)","ACTIVE_COMPARATOR","Description: Female athletes using oral contraceptives, following a continuous intensity training program regardless of menstrual phase. This group serves as a control, providing insight into the neuromuscular effects of training under the hormonal conditions set by oral contraceptive use.\n\nIntervention:\n\nResistance Training Program: 13 weeks, 2 sessions per week, with continuous intensity across all training sessions due to the stable hormonal environment induced by oral contraceptives.",[23],[30,35,39],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Resistance periodized training program (N-PF)","This intervention consists of a 13-week structured resistance training program tailored to align with the natural menstrual cycle, focusing on intensified training during the follicular phase. Participants perform two resistance training sessions per week, each lasting 90 minutes, with intensity modulated based on the participant's menstrual phase.\n\nIntensity Modulation:\n\nFollicular Phase (Days 1-14): Training sessions are performed at a higher training load during both early and late follicular phases. The increased intensity leverages higher estrogen levels, which may support greater muscle strength and recovery during this phase.\n\nLuteal Phase (Days 15-28): Training sessions are conducted at a lower training load during both early and late luteal phases to accommodate the hormonal shifts associated with elevated progesterone.",[9],null,{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"Resistance peioridized training program (N-PL)","This intervention consists of a 13-week structured resistance training program tailored to align with the natural menstrual cycle, focusing on intensified training during the luteal phase. Participants perform two resistance training sessions per week, each lasting 90 minutes, with intensity modulated according to the participant's menstrual phase.\n\nIntensity Modulation:\n\nFollicular Phase (Days 1-14): Training sessions are conducted at a lower training load during both early and late follicular phases to accommodate the hormonal environment of this phase.\n\nLuteal Phase (Days 15-28): Training sessions are performed at a higher training load during both early and late luteal phases. The increased intensity leverages the hormonal environment associated with elevated progesterone, which may affect muscle endurance and neuromuscular adaptations during this phase.",[15],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":34},"Continuous resistance training program (C)","This intervention consists of a 13-week structured resistance training program with a continuous training intensity maintained throughout the menstrual cycle. Participants perform two resistance training sessions per week, each lasting 90 minutes, with a consistent training load applied across all phases.\n\nIntensity Modulation:\n\nAll Phases: Training sessions are conducted at a steady training load regardless of menstrual phase. This continuous approach is designed to provide a baseline for assessing neuromuscular adaptations without the influence of phase-specific intensity adjustments.",[20,25],[44,48],{"name":45,"affiliation":46,"role":47},"Nicolas PEYROT, Professor (PU)","Université du Mans","STUDY_DIRECTOR",{"name":49,"affiliation":5,"role":47},"Manon DAUVERGNE, Professor (Assistant)",[51,56],{"name":52,"role":53,"phone":54,"phoneExt":34,"email":55},"Manon DAUVERGNE, PhD student","CONTACT","+262693463288","manon.dauvergne@univ-reunion.fr",{"name":57,"role":53,"phone":58,"phoneExt":34,"email":59},"Josué GAN, Msc.","+33680306613","gan.josue@gmail.com",[61],{"facility":62,"status":63,"city":64,"state":65,"zip":66,"country":67,"countryCode":34,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Laboratoire IRISSE (Université de La Réunion)","RECRUITING","Le Tampon","France","97430","Reunion",{"type":69,"coordinates":70},"Point",[71,72],55.51766,-21.2766,{"lat":72,"lon":71},[75],{"name":76,"role":53,"phone":54,"phoneExt":34,"email":55},"Manon DAUVERGNE, PhD",{"type":78,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Manon DAUVERGNE","PhD Candidate",[82],{"name":83,"class":84},"Physio Formation","UNKNOWN","100568305","impact-of-menstrual-cycle-based-resistance-training-on-neuromuscular-performance-in-female-athletes-100568305",false,"NCT06679491","Impact of Menstrual Cycle-Based Resistance Training on Neuromuscular Performance in Female Athletes","Effects of Menstrual Cycle-based Undulating Periodized Resistance Training in Women's Neuromuscular Abilities","MENSES","Inclusion Criteria:\n\n* Female athletes with natural menstrual cycles (eumenorrheic): Participants must have regular menstrual cycles lasting between 21 and 35 days, with at least 9 cycles per year.\n* Women using a low-dose monophasic estrogen-progestin oral contraceptive.\n* Age 18 or older: Participants must be legal adults.\n* Body Mass Index (BMI) between 18 and 30 kg\u002Fm².\n* No medical contraindications to high-level physical training or exercise.\n* Physically active: Engages in at least 3 hours of physical activity per week.\n* Informed consent: Provides written, informed consent to participate in the study.\n* Affiliation with a social security system (if applicable by local regulations).\n\nExclusion Criteria:\n\n\\-",true,"FEMALE","18 Years",{"count":97,"type":98},60,"ESTIMATED","INTERVENTIONAL",[101],"NA","The goal of this clinical trial is to assess the impact of menstrual cycle-based resistance training on neuromuscular function in female athletes.\n\nThe primary questions it aims to answer are :\n\n* Does varying resistance training intensity according to menstrual phases improve maximal knee extensor strength?\n* How do different training protocols affect voluntary activation, rate of force development, muscle stiffness, and vertical jump height?\n\nResearchers will compare natural menstrual cycle groups with an oral contraceptive control group to determine if menstrual phase-specific training influences neuromuscular adaptations.\n\nParticipants will:\n\n* Undergo 2 weekly resistance training sessions over 13 weeks with intensity adjustments based on menstrual phase\n* Complete periodic neuromuscular assessments across three menstrual phases: early follicular, late follicular, and mid-luteal before and after resistance training intervention",[104,105,106,107,108,109,110,111,112],"Menstrual Cycle","Resistance Training","Neuromuscular Function","Female Athlete","Women Health","Oral Contraceptive Pill","Muscle Strenght","Hormones","Periodized Training",[104,114,115,116,117,111,118,119],"Resistance training","Periodized training","neuromuscular function","Female athlete","oral contraceptive pill","women health","2024-11-05",{"date":122,"type":123},"2024-11-07","ACTUAL",{"date":125,"type":98},"2024-11-01",{"date":127,"type":98},"2027-12-31",{"name":5,"class":6},1]