[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542294":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":10,"responsibleParty":29,"collaborators":10,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":10,"eligibilityCriteria":38,"healthyVolunteers":35,"sex":39,"minAge":10,"maxAge":10,"enrollmentInfo":40,"targetDuration":10,"studyType":43,"phases":44,"briefSummary":46,"conditions":47,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients with mitral stenosis",null,[12],"Device: Transesophageal echocardiography",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","Transesophageal echocardiography","* D.Echocardiography(Transthoracic and transesophageal):\n* 2D echocardiography (to detect LA function, severity of MS and Wilkins score).\n\nThe following conventional parameters were measured :\n\n* left atrial volume index (LAVi), and left ventricular ejection fraction (LVEF) by modified biplane Simpson's rule , left atrial emptying fraction calculated as (LAVi max-LAVi min)\u002FLAVi max × 100 ,\\]degree of concomitant mitral regurgitation. The maximum and minimum LAA areas were measured by planimetry. LAA area change (%) was calculated using the following formula: LAA area change = \\[(maximal LAA area-minimal LAA area)\u002Fmaximal LAA area\\] × 100.\n* Transesophageal echocardiogram (TEE) (to detect LAA function) .\n* LAA flow velocity patterns by pulsed-wave Doppler\n* Early diastolic emptying velocity\n* Late diastolic emptying velocity or LAA contraction flow\n* LAA filling velocity\n* Systolic reflection waves\n* Two-Dimensional- LAA fractional area change (LAAAC%)",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Mohamed Ismail","CONTACT","01091806181","prep.ismail@gmail.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Hamdy shames eddin","01065601161","Ashams98@gmail.com",{"type":30,"investigatorFullName":31,"investigatorTitle":32,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mohamed Ahmed Ali Ismail","Resident","100542294","impact-of-percutaneous-transvenous-mitral-commissurotomy-on-the-left-atrial-appendage-function-in-patients-with-mitral-stenosis-100542294",false,"NCT06340997","Impact of Percutaneous Transvenous Mitral Commissurotomy on The Left Atrial Appendage Function in Patients With Mitral Stenosis.","Inclusion Criteria:\n\n* • Patient eligible for PTMC as anatomical characteristics àpatient with sever MS (area 1.5cm2, echocardiographic score (Wilkins score ≤ 8, Cormier score 1 and 2 …), contraindication or high risk to surgical MVR.\n\nExclusion Criteria:\n\n* Patient with mitral regurgitation more than grade II .\n* Patient not eligible to PTMC.\n* Patient with severe heart failure (NHYA class IV) .\n* Patient with previous Cerebrovascular accident .\n* Patient with contraindication to TEE ( esophageal disease like stricture , diverticuli, varices, …, uncooperative patient )","ALL",{"count":41,"type":42},25,"ESTIMATED","INTERVENTIONAL",[45],"NA","• Evaluation of the effect of PTMC on LAA function by TEE at least one month after the procedure and its effectiveness in prevention of thrombi formation and cerebrovascular complications.",[48],"Mitral Stenosis","NOT_YET_RECRUITING","2024-03-25",{"date":52,"type":53},"2024-04-02","ACTUAL",{"date":55,"type":42},"2024-07-01",{"date":57,"type":42},"2027-08-01",{"name":5,"class":6}]