[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100398538":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":123,"collaborators":126,"id":129,"slug":130,"hasResults":131,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":10,"eligibilityCriteria":135,"healthyVolunteers":131,"sex":136,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":10,"studyType":142,"phases":10,"briefSummary":143,"conditions":144,"keywords":147,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":159},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Surgical group",null,"Individuals with cystic fibrosis and chronic rhinosinusitis who undergo endoscopic sinus surgery",{"label":13,"type":10,"description":14,"interventionNames":10},"Medical group","Individuals with cystic fibrosis and chronic rhinosinusitis who do not undergo endoscopic sinus surgery",[16],{"name":17,"affiliation":5,"role":18},"Daniel M Beswick, MD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","310-206-8457","dbeswick@mednet.ucla.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Marlene Florian","424-946-5862","mflorian@mednet.ucla.edu",[29,45,54,64,73,83,93,103,113],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Los Angeles","California","90095","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-118.24368,34.05223,{"lat":40,"lon":39},[43,44],{"name":25,"role":21,"phone":10,"phoneExt":10,"email":27},{"name":17,"role":18,"phone":10,"phoneExt":10,"email":10},{"facility":46,"status":30,"city":47,"state":32,"zip":48,"country":34,"countryCode":35,"cosmosGeoPoint":49,"geoPoint":53,"contacts":10},"Stanford University","Stanford","94305",{"type":37,"coordinates":50},[51,52],-122.16608,37.42411,{"lat":52,"lon":51},{"facility":55,"status":30,"city":56,"state":57,"zip":58,"country":34,"countryCode":35,"cosmosGeoPoint":59,"geoPoint":63,"contacts":10},"University of Colorado","Aurora","Colorado","80045",{"type":37,"coordinates":60},[61,62],-104.83192,39.72943,{"lat":62,"lon":61},{"facility":65,"status":30,"city":66,"state":57,"zip":67,"country":34,"countryCode":35,"cosmosGeoPoint":68,"geoPoint":72,"contacts":10},"National Jewish Health","Denver","80206",{"type":37,"coordinates":69},[70,71],-104.9847,39.73915,{"lat":71,"lon":70},{"facility":74,"status":30,"city":75,"state":76,"zip":77,"country":34,"countryCode":35,"cosmosGeoPoint":78,"geoPoint":82,"contacts":10},"University of North Carolina","Chapel Hill","North Carolina","27514",{"type":37,"coordinates":79},[80,81],-79.05584,35.9132,{"lat":81,"lon":80},{"facility":84,"status":30,"city":85,"state":86,"zip":87,"country":34,"countryCode":35,"cosmosGeoPoint":88,"geoPoint":92,"contacts":10},"Oregon Health Science University","Portland","Oregon","97239",{"type":37,"coordinates":89},[90,91],-122.67621,45.52345,{"lat":91,"lon":90},{"facility":94,"status":30,"city":95,"state":96,"zip":97,"country":34,"countryCode":35,"cosmosGeoPoint":98,"geoPoint":102,"contacts":10},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":37,"coordinates":99},[100,101],-79.93275,32.77632,{"lat":101,"lon":100},{"facility":104,"status":30,"city":105,"state":106,"zip":107,"country":34,"countryCode":35,"cosmosGeoPoint":108,"geoPoint":112,"contacts":10},"Vanderbilt University Medical Center","Nashville","Tennessee","37232",{"type":37,"coordinates":109},[110,111],-86.78444,36.16589,{"lat":111,"lon":110},{"facility":114,"status":30,"city":115,"state":116,"zip":117,"country":34,"countryCode":35,"cosmosGeoPoint":118,"geoPoint":122,"contacts":10},"University of Utah","Salt Lake City","Utah","84132",{"type":37,"coordinates":119},[120,121],-111.89105,40.76078,{"lat":121,"lon":120},{"type":18,"investigatorFullName":124,"investigatorTitle":125,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Daniel M. Beswick","Assistant Professor-in-Residence",[127],{"name":128,"class":6},"Cystic Fibrosis Foundation","100398538","impact-of-sinus-surgery-on-individuals-with-cystic-fibrosis-100398538",false,"NCT04469439","Impact of Sinus Surgery on Individuals With Cystic Fibrosis","The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy","Inclusion Criteria:\n\n1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).\n2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and\u002For sweat chloride\n3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines\n4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment\n5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment\n\nExclusion Criteria:\n\n1. Underwent endoscopic sinus surgery in past 12 months\n2. Will obtain follow up care at non-participating institutions\n3. Unable to complete follow-up surveys","ALL","18 Years","99 Years",{"count":140,"type":141},170,"ESTIMATED","OBSERVATIONAL","This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.",[145,146],"Chronic Rhinosinusitis (Diagnosis)","Cystic Fibrosis",[148,146,149],"Chronic Rhinosinusitis","Endoscopic Sinus Surgery","2026-04-17",{"date":152,"type":153},"2026-04-22","ACTUAL",{"date":155,"type":153},"2020-07-01",{"date":157,"type":141},"2027-01-31",{"name":5,"class":6},9]