[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471583":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":61,"collaborators":63,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":25,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Rhode Island Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Shortened Sleep","EXPERIMENTAL","In this 4-week sleep protocol, children in this experimental condition follow a Stabilized Sleep schedule (i.e., their usual bed time) during weeks 1, 3 and 4. During week 2, they follow a Shortened Sleep schedule, during which they go to bed 90 later than is typical.",[13],"Behavioral: Shortened Sleep",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Sleep Schedule","ACTIVE_COMPARATOR","In this control arm of the 4-week sleep protocol, children follow the Stabilized Sleep schedule for all 4 weeks.",[19],"Behavioral: Stabilized sleep",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","In this experimental condition, children go to bed 90 minutes later than their typical bedtime during Week 2 of the 4-week protocol.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Stabilized sleep","In this control condition, children go to bed at their usual time throughout the 4-week protocol.",[15],[31],{"name":32,"affiliation":5,"role":33},"Daphne Koinis-Mitchell, PhD","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","401-793-8632","dkoinismitchell@lifespan.org",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Sheryl J Kopel, MSc","401 444-7217","sjkopel@lifespan.org",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Providence","Rhode Island","02903","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-71.41283,41.82399,{"lat":55,"lon":54},[58,59],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":40,"role":36,"phone":60,"phoneExt":25,"email":42},"401-444-7217",{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[64,66],{"name":65,"class":6},"Brown University",{"name":67,"class":6},"University of Mississippi Medical Center","100471583","impact-of-sleep-duration-on-immune-balance-in-urban-children-with-asthma-100471583",false,"NCT05420766","Impact of Sleep Duration on Immune Balance in Urban Children With Asthma","AIMS","Inclusion:\n\n* Children 7-11 years old\n* Has physician-diagnosed asthma, per parent and pediatrician report\n* Meets criteria for current persistent asthma with a current prescription for an asthma controller medicine\n* Obtains 9.0-11.0 h of sleep per 24 h day in the past month\n* Has a positive allergy skin test performed at the clinic visit\n* Resides and attend school in one of the targeted urban areas (Rhode Island: East Providence, North Providence, Providence, Warwick, Cranston, Woonsocket, Central Falls, Pawtucket, Lincoln, Johnston. Massachusetts: Attleboro, North Attleboro, Fall River.\n* Has a primary caregiver who speaks English\n\nExclusion:\n\n* No asthma diagnosis\n* No use of asthma controller medication\n* Severe persistent asthma that is poorly controlled\n* Diagnosis of additional pulmonary disease or medical condition or immune deficiency disorders\n* Use of systemic steroids \\\u003C30 days of screening\n* Asthma-related emergency department visit and\u002For asthma-related hospitalization in past 90 days\n* Marked developmental delay, psychiatric conditions, academic\u002Fbehavioral problems, learning disabilities\n* Tanner stage 3-5 of pubertal development\n* Diagnosed ADHD; Use of stimulants to treat ADHD\n* An Apnea-Hypoxia Index \\>5 (indicator of sleep disordered breathing)","ALL","7 Years","11 Years",{"count":79,"type":80},204,"ESTIMATED","INTERVENTIONAL",[83],"NA","Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.",[86,87,88],"Asthma in Children","Sleep Hygiene","Sleep, Inadequate",[87,90,91],"Children with asthma","Immune function in children","2025-09-19",{"date":94,"type":95},"2025-09-22","ACTUAL",{"date":97,"type":95},"2022-05-15",{"date":99,"type":80},"2026-07-31",{"name":5,"class":6},1]