[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628149":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":28,"responsibleParty":44,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Erasme University Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Pre-reimbursement (Jan 1st, 2016 - march 31st, 2020)",null,"Patients undergoing complex cardiac surgery before fibrinogen reimbursement",{"label":13,"type":10,"description":14,"interventionNames":10},"Post-reimbursement (April 1st, 2020- Dec 31st, 2024)","Patients undergoing complex cardiac surgery after fibrinogen reimbursement",[16],{"name":17,"affiliation":18,"role":19},"Caroline Van Aelbrouck, MD","H.U.B - Hôpital Erasme","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+3225553324","c.vanaelbrouck@hubruxelles.be",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Laurent Perrin, MD","laurent.perrin@hubruxelles.be",[29],{"facility":18,"status":10,"city":30,"state":10,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Brussels","1070","Belgium","BE",{"type":35,"coordinates":36},"Point",[37,38],4.34878,50.85045,{"lat":38,"lon":37},[41,42,43],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},{"name":17,"role":19,"phone":10,"phoneExt":10,"email":10},{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100628149","impact-of-the-reimbursement-of-fibrinogen-in-cardiac-surgery-100628149",false,"NCT07457879","Impact of the Reimbursement of Fibrinogen in Cardiac Surgery","Impact of the Reimbursement of Fibrinogen on Transfusion, Mortality and Morbidity in Cardiac Surgery","Inclusion Criteria:\n\n* Patients aged ≥ 18 years\n* Complex cardiac surgery under cardiopulmonary bypass (CPB), defined as:\n\n  1. Coronary artery bypass grafting combined with valve replacement\n  2. Replacement of two or more valves\n  3. Cardiac reoperation\n  4. Surgery for infective endocarditis\n  5. Ascending aorta surgery\n* Scheduled or emergency procedures\n* Complete clinical and biological data available (transfusions, hospital stay, complications, tests)\n* Surgery performed between Jan 1st, 2016 and Dec 31st, 2024\n\nExclusion Criteria:\n\n* Surgery without cardiopulmonary bypass (CPB)\n* Patients aged \\\u003C 18 years\n* Pregnancy\n* Patients requiring postoperative extracorporeal membrane oxygenation (ECMO)","ALL","18 Years",{"count":56,"type":57},450,"ESTIMATED","OBSERVATIONAL","This retrospective, single-center observational study aims to evaluate the impact of fibrinogen concentrate reimbursement introduced in Belgium in April 1st, 2020, on transfusion practices in complex cardiac surgery. Adult patients undergoing complex cardiac surgery with cardiopulmonary bypass between Jan 1st 2016 and Dec 31st 2024 at Erasme Hospital will be included. Transfusion strategies and clinical outcomes will be compared between the pre-reimbursement and post-reimbursement periods.",[61],"Cardiac Surgery",[63,64,65,66,67,68],"Cardiac surgery","Fibrinogen","Blood transfusion","Hemostasis","Transfusion practice","Perioperative bleeding","NOT_YET_RECRUITING","2026-03-03",{"date":72,"type":73},"2026-03-09","ACTUAL",{"date":75,"type":57},"2026-03-20",{"date":77,"type":57},"2026-06-10",{"name":5,"class":6},1]