[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557493":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":39,"centralContacts":43,"locations":53,"responsibleParty":73,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":11,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":11,"overallStatus":56,"whyStopped":11,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Laval University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Diet N-P-","EXPERIMENTAL",null,[13],"Other: Diet N-P-",{"label":15,"type":10,"description":11,"interventionNames":16},"Diet N+P-",[17],"Other: Diet N+P-",{"label":19,"type":10,"description":11,"interventionNames":20},"Diet N-P+",[21],"Other: Diet N-P+",{"label":23,"type":10,"description":11,"interventionNames":24},"Diet N+P+",[25],"Other: Diet N+P+",[27,30,33,36],{"type":6,"name":9,"description":28,"armGroupLabels":29,"otherNames":11},"Low in saturated fatty acids (SFAs), free sugar and sodium; Low in ultra-processed foods (UPFs)",[9],{"type":6,"name":15,"description":31,"armGroupLabels":32,"otherNames":11},"Rich in SFAs, free sugar and sodium; Low in UPFs",[15],{"type":6,"name":19,"description":34,"armGroupLabels":35,"otherNames":11},"Low in SFAs, free sugar and sodium; High in UPFs",[19],{"type":6,"name":23,"description":37,"armGroupLabels":38,"otherNames":11},"Rich in SFAs, free sugar and sodium; High in UPFs",[23],[40],{"name":41,"affiliation":5,"role":42},"Benoît Lamarche, PhD","PRINCIPAL_INVESTIGATOR",[44,48],{"name":41,"role":45,"phone":46,"phoneExt":11,"email":47},"CONTACT","418-656-3527","benoit.lamarche@fsaa.ulaval.ca",{"name":49,"role":45,"phone":50,"phoneExt":51,"email":52},"Iris Gigleux, MSc","418-656-2131","405087","Iris.Gigleux@fsaa.ulaval.ca",[54],{"facility":55,"status":56,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Centre Nutrition, santé et société (NUTRISS), INAF, Université Laval","RECRUITING","Québec","Quebec","G1V 0A6","Canada","CA",{"type":63,"coordinates":64},"Point",[65,66],-71.21454,46.81228,{"lat":66,"lon":65},[69,70,72],{"name":41,"role":45,"phone":46,"phoneExt":11,"email":47},{"name":49,"role":45,"phone":50,"phoneExt":51,"email":71},"iris.gigleux@fsaa.ulaval.ca",{"name":41,"role":45,"phone":11,"phoneExt":11,"email":11},{"type":42,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Benoit Lamarche","Study director",[77],{"name":78,"class":79},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV","100557493","impact-of-ultra-processed-foods-on-cardiometabolic-risk-factors-100557493",false,"NCT06538831","Impact of Ultra-processed Foods on Cardiometabolic Risk Factors","A 2x2 Factorial Randomized Controlled Trial to Elucidate How Ultra-processed Foods Modulate Cardiometabolic Risk","NOVA","Inclusion Criteria:\n\n* Body mass index (BMI):18 to 35 kg\u002Fm2\n* Stable weight over the last 3 months (variation of less than 5 kg)\n* LDL-cholesterol \\\u003C 5.0 mmol\u002FL\n* HbA1c \\\u003C 6.5%\n* Office blood pressure \\\u003C150\u002F90 mmHg\n* Non-smokers or smokers of less than 10 cigarettes a day\n\nExclusion Criteria:\n\n* Pregnant or breast-feeding women\n* Alcohol consumption of more than 7 drinks per week\n* Women: contraceptives for less than 3 months or hormone therapy for less than 6 months\n* Medication to treat hypercholesterolemia, diabetes or hypertension\n* Diagnosis of cardiovascular disease, diabetes, hypertension, cancer\n* Food allergies or aversions to any of the foods on the experimental menus\n* Being on a diet or following a special diet\n* Daytime MAPA blood pressure \\>150\u002F90",true,"ALL","18 Years","75 Years",{"count":93,"type":94},120,"ESTIMATED","INTERVENTIONAL",[97],"NA","The goal of this clinical trial is to examine in a 2x2 factorial RCT what feature(s) of ultra-processed foods (UPFs) contribute to cardiometabolic risk in men and women. The project's hypotheses are :\n\n1. that the nutrient composition of UPFs (high SFA, free sugar and sodium) per se has deleterious impacts on cardiometabolic risk factors;\n2. that the industrial techniques and processes of UPFs per se do not.\n\nParticipants will be randomly assigned to one of 4 groups consistent with the 2x2 factorial design of the study: 1- the nutrient composition of foods (low vs. high in SFA, free sugar and sodium) and 2- the degree of industrial techniques and food processing (little to no vs.important amounts of UPFs). All foods will be provided to participants under isocaloric conditions during the 6-week dietary intervention. Participants will have to consume one of the 4 experimental diets for 6 weeks.",[100],"Cardiometabolic Risk","2024-10-15",{"date":103,"type":104},"2024-10-17","ACTUAL",{"date":106,"type":104},"2024-09-25",{"date":108,"type":94},"2028-08-31",{"name":5,"class":6},1]