[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100488978":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":28,"locations":37,"responsibleParty":72,"collaborators":10,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":76,"sex":82,"minAge":83,"maxAge":10,"enrollmentInfo":84,"targetDuration":87,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":98,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Romanian Society for Enteral and Parenteral Nutrition","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A",null,"Group A - enteral formula with 6.3 g\u002F100 ml protein",[13],"Other: Medical food",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","enteral formula with 10 g\u002F100 ml protein",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Medical food","enteral formulas with different protein composition",[9,15],[24],{"name":25,"affiliation":26,"role":27},"Ioana Grintescu, MD, PhD","Romanian Society of Enteral and Parenteral Nutrition","STUDY_DIRECTOR",[29,33],{"name":25,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","+40722329187","ioana.grintescu@rospen.ro",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Cristian Cobilinschi, MD, PhD","+40765018776","cristian.cobilinschi@umfcd.ro",[38],{"facility":39,"status":40,"city":41,"state":10,"zip":10,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Clinical Emergency Hospital of Bucharest","RECRUITING","Bucharest","Romania","RO",{"type":45,"coordinates":46},"Point",[47,48],26.10626,44.43225,{"lat":48,"lon":47},[51,53,54,57,59,60,61,63,66,68,70],{"name":52,"role":30,"phone":31,"phoneExt":10,"email":32},"Ioana Grințescu, Professor",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},{"name":55,"role":56,"phone":10,"phoneExt":10,"email":10},"Liliana Mirea, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":58,"role":56,"phone":10,"phoneExt":10,"email":10},"Raluca Ungureanu, MD, PhD",{"name":34,"role":56,"phone":10,"phoneExt":10,"email":10},{"name":25,"role":56,"phone":10,"phoneExt":10,"email":10},{"name":62,"role":56,"phone":10,"phoneExt":10,"email":10},"Ana Maria Cotae, MD",{"name":64,"role":65,"phone":10,"phoneExt":10,"email":10},"Diana Iacob, MD","SUB_INVESTIGATOR",{"name":67,"role":65,"phone":10,"phoneExt":10,"email":10},"Angela Popa, MD",{"name":69,"role":65,"phone":10,"phoneExt":10,"email":10},"Ioana Dumitru, MD",{"name":71,"role":65,"phone":10,"phoneExt":10,"email":10},"Mihaela Buiuc, MD",{"type":73,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100488978","impact-of-very-high-protein-content-enteral-nutrition-formulas-on-critically-ill-multiple-trauma-patients-100488978",false,"NCT05647135","ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts","ImpACt of Very High Protein Content Enteral nUtrition Formulas on Protein Metabolism and Residual Gastric Volume in Critically Ill MUltipLe trAuma paTiEnts","ACCUMULATE","Inclusion Criteria:\n\n* Adult patients (\\>18 yrs) admitted to the ICU\n* Multiple trauma (Injury severity score \\> 18)\n* Intubation and mechanical ventilation upon admission in ICU or during the first 24 hours of admission, for at least 48 h\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Pregnant women\n* Patients not intubated or not mechanically ventilated or receiving only non-invasive ventilation\n* Patients with enteral feeding contraindication 48 h after admission\n* Patients with recent gastrointestinal surgical intervention\n* Patients on chronic therapy with corticosteroids","ALL","18 Years",{"count":85,"type":86},70,"ESTIMATED","8 Weeks","OBSERVATIONAL","This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with normal protein content.\n\n* Differences regarding achieving protein and calorie daily targets when using enteral nutrition formulas with different protein content\n* Differences regarding residual gastric volume when using enteral nutrition formulas with different protein content\n* Differences regarding body composition when using enteral nutrition formulas with different protein content",[91,92,93,94,95,96,97],"Metabolism","Trauma","Nutritional Deficiency","Protein Malnutrition","Gastroparesis","Muscle Loss","Calorie Malnutrition Protein",[99,100,101,102,103,104,105],"enteral nutrition","multiple trauma","energy target","protein target","body composition","gastric residual volume","enteral nutrition intolerance","2024-07-17",{"date":108,"type":109},"2024-07-22","ACTUAL",{"date":111,"type":109},"2023-03-01",{"date":113,"type":86},"2024-12-01",{"name":5,"class":6},1]