[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473300":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":37,"locations":47,"responsibleParty":72,"collaborators":74,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":41,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":101,"overallStatus":50,"whyStopped":41,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Istituto Auxologico Italiano","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Rehabilitation","EXPERIMENTAL","Multidisciplinary rehabilitation program consisting of diet and physical exercise for 4 weeks.",[13],"Other: Rehabilitation program",{"label":15,"type":10,"description":16,"interventionNames":17},"Whole-Body Cryotherapy","Rehabilitation program consisting of 10 WBC sessions over two weeks.",[18,13],"Other: Whole-body cryostimulation (WBC)",[20,26],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Whole-body cryostimulation (WBC)","Multidisciplinary rehabilitation program consisting of 10 WBC sessions.",[15],[25],"Whole-body cryotherapy",{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Rehabilitation program","Multidisciplinary rehabilitation program consisting of diet and physical exercise.",[9,15],[31],"Multidisciplinary Rehabilitation program",[33],{"name":34,"affiliation":35,"role":36},"Paolo Capodaglio, Prof, MD","IRCCS Istituto Auxologico Italiano","PRINCIPAL_INVESTIGATOR",[38,43],{"name":34,"role":39,"phone":40,"phoneExt":41,"email":42},"CONTACT","+39 0323514331",null,"p.capodaglio@auxologico.it",{"name":44,"role":39,"phone":45,"phoneExt":41,"email":46},"Jacopo Maria Fontana, PhD","+39 3534297935","j.fontana@auxologico.it",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"IRCCS Istituto Auxologico Italiano Ospedale San Giuseppe","RECRUITING","Oggebbio","Verbano-Cusio-Ossola","28845","Italy","IT",{"type":57,"coordinates":58},"Point",[59,60],8.64663,45.99088,{"lat":60,"lon":59},[63,65,68,70],{"name":44,"role":39,"phone":64,"phoneExt":41,"email":46},"+393534297935",{"name":66,"role":67,"phone":41,"phoneExt":41,"email":41},"Paolo Piterà","SUB_INVESTIGATOR",{"name":69,"role":67,"phone":41,"phoneExt":41,"email":41},"Amelia Brunani",{"name":71,"role":36,"phone":41,"phoneExt":41,"email":41},"Paolo Capodaglio",{"type":73,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[75,77],{"name":76,"class":6},"Politecnico di Milano",{"name":78,"class":6},"Università degli Studi di Brescia","100473300","impact-of-wbc-on-patients-with-metabolic-or-neurological-diseases-or-fibromyalgia-wbc-menefi-100473300",false,"NCT05443100","Impact of WBC on Patients With Metabolic or Neurological Diseases or Fibromyalgia (WBC-MeNeFi)","A Non-randomized Pilot Study of the Impact on Rehabilitation Outcomes of a Course of Whole-body Cryostimulation (WBC) Treatment on Patients With Metabolic or Neurological Diseases or Fibromyalgia","WBC-MeNeFi","Inclusion Criteria:\n\n* both sexes\n* age 18-65 yrs\n* BMI \\> 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* severe psychiatric conditions\n* acute respiratory disease\n* acute cardiovascular disease\n* unstable hypertension\n* cold intolerance\n* claustrophobia\n* pregnancy\n* recent modification of usual drug treatment\n* previous treatment with WBC\n* weight loss in the last 3 months\n* body temperature greater than 37.5°C.","ALL","18 Years","65 Years",{"count":91,"type":92},300,"ESTIMATED","INTERVENTIONAL",[95],"NA","The purpose of this clinical trial is to investigate on different types of patients the effects of 10 sessions of whole-body cryostimulation (WBC): 1) in patients with obesity (BMI \\> 30), we want to investigate whether WBC increases thermogenesis, basal metabolic rate (BMR), respiratory quotient (which indirectly provides an estimate of energy substrate oxidation), reduces chronic inflammatory status, fatigue and pain, and improves functional abilities and general physical and psychological capacities; 2) in patients diagnosed with fibromyalgia and\u002For osteoarthrytis, we want to investigate the reduction of pain, inflammatory status, increase in functional capacity and general physical and psychological abilities, and improvement in mood; 3) in neurological patients diagnosed with Parkinson's disease, Multiple Sclerosis, and Disimmune Polyneuropathies, the effects of WBC on pain, fatigue, and sleep quality are to be investigated; 4) in normal\u002Foverweight (BMI\\\u003C30 kg\u002Fm2) subjects, the effects of WBC on all parameters described previously for the other protocols are to be investigated. Specifically, for all enrolled subjects, we want to assess blood catecholamine levels, investigate the effects of sympathetic response on body composition, blood pressure, heart rate, lipid profile, and physical performance. Three hundred patients admitted for a rehabilitation program (diet + physiotherapy + exercise) will be non-randomly assigned to either a group following the program (R) or a group additionally receiving ten 2-3 minute WBC sessions at -110°C over two weeks (RWBC).",[98,99,100],"Obesity","Fibromyalgia","Neurological Conditions",[102,98,9,103,104],"Whole-Body cryostimulation","Catecholamines","Thermal stress","2025-08-01",{"date":107,"type":108},"2025-08-04","ACTUAL",{"date":110,"type":108},"2019-04-01",{"date":112,"type":92},"2026-12-30",{"name":5,"class":6},1]