[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644117":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":39,"locations":45,"responsibleParty":68,"collaborators":72,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":10,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":10,"enrollmentInfo":83,"targetDuration":10,"studyType":86,"phases":10,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Tampere University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients",null,"DVT detected on other lower limb, undergoing catheter-directed thrombolysis",[13,14,15],"Device: Impedance plethysmography IPG","Device: Venous Occlusion Plethysmography VOP","Other: Breathing and leg movement exercise",{"label":17,"type":10,"description":17,"interventionNames":18},"Healthy volunteers",[13,14,15],[20,27,33],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Impedance plethysmography IPG","IPG signal is measured with ThrombUS+ prototype device",[17,9],[26],"IPG",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Venous Occlusion Plethysmography VOP","In VOP measurement, a temporal blood restriction is caused by an occlusive cuff blocking venous outflow but allowing arterial inflow. The cuff intervention causes a change in venous blood volume, and it can be measured by electrical impedance plethysmography (IPG).",[17,9],[32],"VOP",{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Breathing and leg movement exercise","The first exercise is the Valsalva maneuver, where the subject first inhales and then pushes out the breath while the larynx is closed. In the second exercise, the subject inhales for approximately 10 seconds, holds the breath for approximately 5 seconds, and then breathes out. Finally, the subject moves the ankles to contract calf muscles, and further to cause changes in venous blood volume. The IPG signal is measured on both calves by ThrombUS+ prototype device during these exercises.",[17,9],[38],"Valsalva",[40],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Vehkaoja","CONTACT","+358407393181","antti.vehkaoja@tuni.fi",[46,63],{"facility":47,"status":48,"city":49,"state":10,"zip":10,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Tampere University Hospital","RECRUITING","Tampere","Finland","FI",{"type":53,"coordinates":54},"Point",[55,56],23.78712,61.49911,{"lat":56,"lon":55},[59],{"name":60,"role":42,"phone":61,"phoneExt":10,"email":62},"Oksala","+3583311611","niku.oksala@tuni.fi",{"facility":5,"status":64,"city":49,"state":10,"zip":10,"country":50,"countryCode":51,"cosmosGeoPoint":65,"geoPoint":67,"contacts":10},"COMPLETED",{"type":53,"coordinates":66},[55,56],{"lat":56,"lon":55},{"type":69,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Antti Vehkaoja","Professor",[73],{"name":47,"class":6},"100644117","impedance-plethysmography-based-deep-vein-thrombosis-monitoring-during-catheter-directed-thrombolysis-100644117",false,"NCT07665320","Impedance Plethysmography Based Deep Vein Thrombosis Monitoring During Catheter-directed Thrombolysis","Inclusion Criteria for Patients group:\n\n* Age: 18 or older;\n* DVT detected on other lower limb;\n* Suitable for CDT treatment;\n* Ability to give informed consent;\n* Volunteering for the study.\n\nExclusion Criteria for Patients group:\n\n* Age under 18 years;\n* Inability to give informed consent;\n* Denial;\n* Too injured skin in the measurement area\n\nInclusion Criteria for Healthy volunteers group:\n\n* Age: 18 or older;\n* Ability to give informed consent;\n* Volunteering for the study\n\nExclusion Criteria for Healthy volunteers group:\n\n* Diagnosed DVT in lower limbs;\n* Age under 18 years;\n* Inability to give informed consent;\n* Denial;\n* Too injured skin in the measurement area.",true,"ALL","18 Years",{"count":84,"type":85},40,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to collect data on blood circulation using a multi-frequency impedance plethysmography device developed in the ThrombUS+ project. Impedance plethysmography (IPG) is a non-invasive method that measures changes in blood volume using electrodes placed on the skin. The collected data will be used for device development, the improvement of diagnostic data analysis methods, and AI training.\n\nA total of 40 participants will be recruited for this study, with 20 healthy volunteers in Tampere University and 20 patients undergoing thrombolytic therapy for DVT at Tampere University Hospital.",[89],"Deep Vein Thrombosis (DVT)",[91,92],"deep vein thrombosis","DVT","2026-06-24",{"date":95,"type":96},"2026-06-29","ACTUAL",{"date":98,"type":96},"2025-07-17",{"date":100,"type":85},"2027-12",{"name":5,"class":6},2]