[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618913":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":20,"responsibleParty":31,"collaborators":33,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":20,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":20,"enrollmentInfo":45,"targetDuration":20,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":58,"overallStatus":64,"whyStopped":20,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":20},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Guideline Implementation Group","EXPERIMENTAL","Participants in this single-arm study will receive an evidence-based, context-adapted clinical nutrition practice guideline implemented in surgical intensive care units (ICUs) using an i-PARIHS-guided translation strategy. The implementation includes guideline localization, expert consensus validation, education and training, on-site facilitation, audit and feedback, and continuous process optimization. Outcomes will be assessed before and after guideline implementation to evaluate changes in healthcare professional adherence to clinical nutrition recommendations and nutrition-related clinical outcomes among surgical critically ill patients.",[13],"Behavioral: Guideline Implementation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Guideline Implementation","This behavioral intervention consists of the implementation of an evidence-based, context-adapted clinical nutrition practice guideline in surgical intensive care units (ICUs), guided by the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework. The intervention includes systematic guideline selection based on existing surgical and critical care nutrition guidelines, contextual adaptation to the Chinese healthcare setting, guideline localization and expert consensus validation, and structured implementation strategies.\n\nKey components of the intervention include education and training of ICU healthcare professionals, on-site facilitation, audit and feedback, and continuous process optimization to support adherence to guideline recommendations. The intervention is delivered at the unit level and integrated into routine clinical practice in surgical ICUs. Outcomes are evaluated using a pre- and post-implementation design to assess changes in healt",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Ru Bin Han, Professor","CONTACT","+86 13701103033","hanbinru8723@163.com",{"name":28,"role":24,"phone":29,"phoneExt":20,"email":30},"Chen Xin, Mr.","+86 17863992191","1014974593@qq.com",{"type":32,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[34],{"name":35,"class":6},"The Affiliated Hospital of Qingdao University","100618913","implementation-of-clinical-nutrition-practice-guidelines-in-surgical-icus-100618913",false,"NCT07337798","Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs","Effects of Implementing Evidence-Based Clinical Nutrition Practice Guidelines in Surgical Intensive Care Units: A Cohort Study","Inclusion Criteria:\n\nFor ICU healthcare professionals:\n\nEmployed at one of the participating study sites (tertiary general hospitals)\n\nHolds a valid Registered Nurse license issued in the People's Republic of China\n\nCurrently working in frontline clinical nursing care in a surgical intensive care unit (ICU) during the study period\n\nAt least 1 year of clinical working experience\n\nAble to understand the study objectives and procedures\n\nWilling to participate and able to provide written informed consent\n\nFor surgical critically ill patients (outcome assessment population):\n\nAged 18 years or older\n\nAdmitted to a surgical ICU due to surgical-related conditions, including trauma, infection, malignancy, or postoperative complications\n\nExpected length of stay in the surgical ICU of at least 48 hours\n\nNo restriction on sex\n\nPatient or legally authorized representative able to provide written informed consent\n\nExclusion Criteria:\n\nFor ICU healthcare professionals:\n\nCurrently pregnant, breastfeeding, or planning pregnancy during the study period\n\nTemporarily assigned, rotating, externally dispatched, on long-term training, or on leave during the study period, making continuous participation impossible\n\nParticipation in other interventional studies that may interfere with the implementation of this study\n\nDetermined by the research team to have cognitive, communication, or other conditions that would make participation inappropriate\n\nFor surgical critically ill patients:\n\nDiagnosed with brain death or awaiting organ donation\n\nPregnant or breastfeeding women\n\nConcurrent participation in other nutrition-related clinical trials","ALL","18 Years",{"count":46,"type":47},200,"ESTIMATED","INTERVENTIONAL",[50],"NA","The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive care units (ICUs) in China. The guideline is selected based on the best available evidence from existing surgical and critical care nutrition guidelines, adapted to the Chinese healthcare context, and implemented using an i-PARIHS-guided translation strategy. The trial involves ICU healthcare professionals working in surgical ICUs of tertiary general hospitals, while assessing nutrition-related clinical outcomes among surgical critically ill patients.\n\nThe main questions it aims to answer are:\n\nDoes guideline implementation improve ICU healthcare professionals' adherence to recommended clinical nutrition practice guidelines?\n\nDoes the implementation of the clinical nutrition practice guideline improve the proportion of surgical critically ill patients who achieve recommended energy and protein intake targets during ICU stay?\n\nResearchers will compare outcomes before and after guideline implementation to determine whether the i-PARIHS-guided guideline translation improves nutrition management processes, healthcare professional performance, and patient-related clinical outcomes.\n\nParticipants will:\n\nComplete baseline and post-implementation assessments related to clinical nutrition knowledge, attitudes, and practices.\n\nParticipate in guideline-based education, training, and implementation activities guided by the i-PARIHS framework.\n\nApply the adapted clinical nutrition practice guideline during routine clinical care in surgical ICUs.\n\nBe evaluated through on-site audits, questionnaires, and clinical data collection during the implementation process.",[53,54,55,56,57],"ICU Patients","Surgical","Nutrition Intervention","Enteral Nutrition","Enteral Nutrition Intolerance",[59,60,61,62,63],"Clinical Nutrition","Surgical Intensive Care Units","i-PARIHS Framework","Implementation Science","Clinical practice guideline","NOT_YET_RECRUITING","2026-01-11",{"date":67,"type":68},"2026-01-13","ACTUAL",{"date":70,"type":47},"2025-12-20",{"date":72,"type":47},"2026-12-31",{"name":5,"class":6}]