[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589358":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":84,"collaborators":86,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":25,"eligibilityCriteria":99,"healthyVolunteers":96,"sex":100,"minAge":101,"maxAge":25,"enrollmentInfo":102,"targetDuration":25,"studyType":105,"phases":106,"briefSummary":108,"conditions":109,"keywords":114,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NMES","EXPERIMENTAL","Neuromuscular Electrical Stimulation (NMES) consists of usual care rehabilitation plus evidence-based implementation of NMES in the early postoperative period to improve physical function after TKA.",[13],"Procedure: NMES",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","ACTIVE_COMPARATOR","The Usual Care clinics will continue clinical practice as normal. Usual Care sites will not have overlap of personnel or training with NMES Sites.",[19],"Other: Usual Care",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","The NMES intervention protocol in this study ensures patients receive NMES intervention that is adequately dosed (dose = treatment minutes x intensity), delivered using evidence-based parameters, and feasible. The investigators will deliver NMES using a portable two-channel stimulator that the investigators have found to produce stronger muscle contractions than other portable NMES units and has been used in previous clinical studies. It also has a built-in compliance meter to monitor patient treatment minutes (adherence) to NMES application. NMES sites will perform routine collection of outcomes as part of standard practice.",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Usual Care clinics will continue with routine collection and documentation of physical performance outcomes as standard practice. A combination of chart reviews and on-site or remote observation will allow for characterization of usual care components for descriptive comparison. Usual Care clinics including the facility, rehabilitation clinicians, and patients will not have access to NMES materials developed for this study.",[15],[30],{"name":31,"affiliation":5,"role":32},"Jennifer Stevens-Lapsley, PT, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Maggie Givan, MA","CONTACT","719.251.7533","maggie.givan@cuanschutz.edu",[40,59,67],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"UCHealth","RECRUITING","Aurora","Colorado","80045","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-104.83192,39.72943,{"lat":52,"lon":51},[55,57],{"name":35,"role":36,"phone":56,"phoneExt":25,"email":38},"719-251-7533",{"name":58,"role":32,"phone":25,"phoneExt":25,"email":25},"Michael Bade, PT, PhD",{"facility":60,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"University of Colorado Denver, Anschutz",{"type":49,"coordinates":62},[51,52],{"lat":52,"lon":51},[65,66],{"name":35,"role":36,"phone":56,"phoneExt":25,"email":38},{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"facility":68,"status":42,"city":69,"state":70,"zip":71,"country":46,"countryCode":47,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Intermountain Health","Murray","Utah","84107",{"type":49,"coordinates":73},[74,75],-111.88799,40.66689,{"lat":75,"lon":74},[78,82],{"name":79,"role":36,"phone":80,"phoneExt":25,"email":81},"Matt Schneider, MBA","801-507-8065","Matthew.Schneider@imail.org",{"name":83,"role":32,"phone":25,"phoneExt":25,"email":25},"Kate Minick, DPT, PhD",{"type":85,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[87,89,91],{"name":88,"class":6},"University of Colorado Health",{"name":90,"class":6},"Intermountain Health Care, Inc.",{"name":92,"class":93},"National Institute on Aging (NIA)","NIH","100589358","implementation-of-neuromuscular-electrical-stimulation-after-total-knee-arthroplasty-100589358",false,"NCT06953375","Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty","Inclusion Criteria:\n\nSite Inclusion Criteria:\n\n• UCHealth or Intermountain Health outpatient physical therapy clinic\n\nPatient Inclusion Criteria:\n\n* Underwent primary unilateral TKA\n* Attended outpatient rehabilitation at a participating clinic within 5 days after TKA\n* Attended at least 3 total outpatient physical therapy visits in total\n\nExclusion Criteria:\n\nPatient Exclusion Criteria:\n\n* NMES Contraindications \\[Patients with implanted cardiovascular cardiovertedefibrillator (ICD), active cancer, post-operative diagnosed deep vein thrombosis (DVT) in involved lower extremity\\]\n* Previous lower extremity arthroplasty less than 12 weeks prior to scheduled TKA surgical date","ALL","18 Years",{"count":103,"type":104},3250,"ESTIMATED","INTERVENTIONAL",[107],"NA","Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but it is drastically underused in rehabilitation practice. This randomized trial will examine the effectiveness and feasibility of a comprehensive strategy for implementing neuromuscular electrical stimulation after knee replacement in two large healthcare organizations.",[110,111,112,113],"Total Knee Arthroplasty","Functional Recovery","Aging","Physical Therapy",[115,116,117,113,118,119,120,121],"NMES (Neuromuscular Electrical Stimulation)","TKA (Total Knee Arthroplasty)","Rehabilitation","RE-AIM: Reach Effectiveness Adoption Implementation Maintenance","Implementation Science","Older Adults","Physical Function","2025-09-25",{"date":124,"type":125},"2025-09-29","ACTUAL",{"date":127,"type":125},"2025-05-12",{"date":129,"type":104},"2029-04",{"name":5,"class":6},3]