[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610280":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":27,"locations":32,"responsibleParty":51,"collaborators":54,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":12,"enrollmentInfo":71,"targetDuration":12,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":35,"whyStopped":12,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Columbia University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care","NO_INTERVENTION","Participants randomized to the standard of care group will receive standard examinations and management of screen positives (ablative therapy or colposcopy referral at a follow-up visit).",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Screen, Triage, and Treat","EXPERIMENTAL","Participants randomized to the screen, triage, and treat group will be examined using the screen and treat approach (same day results and ablative therapy or colposcopy referral, if applicable).",[18],"Other: Screen, Triage, and Treat",[20],{"type":6,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"A screening test is used to determine who is eligible for treatment, eliminating steps related to histological confirmation. Those who meet the HPV criteria will be immediately evaluated for suitability for on-site ablative treatment on the same day. Women not suitable for treatment will be referred for colposcopy and further management at the appropriate facility.",[14],[24],{"name":25,"affiliation":5,"role":26},"Rebecca Schnall, PhD, MPH","PRINCIPAL_INVESTIGATOR",[28],{"name":25,"role":29,"phone":30,"phoneExt":12,"email":31},"CONTACT","212-342-6886","rb897@columbia.edu",[33],{"facility":34,"status":35,"city":36,"state":12,"zip":12,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Clínica de Familia La Romana","RECRUITING","La Romana","Dominican Republic","DO",{"type":40,"coordinates":41},"Point",[42,43],-68.96635,18.42332,{"lat":43,"lon":42},[46],{"name":47,"role":29,"phone":48,"phoneExt":49,"email":50},"Pamela Baez Caraballo, MD, MSc","809-813-2934","130","pamela@clinicadefamilia.org.do",{"type":26,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Rebecca Schnall, RN, MPH, PhD","Professor of Disease Prevention and Health Promotion",[55,58],{"name":56,"class":57},"National Cancer Institute (NCI)","NIH",{"name":59,"class":60},"Clínica de Familia La Romana, Dominican Republic","UNKNOWN","100610280","implementation-of-screen-treat-and-triage-for-women-living-with-hiv-in-la-romana-istar-100610280",false,"NCT07225530","Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)","(iSTAR)","Inclusion Criteria:\n\n* 25 years of age;\n* female sex assigned at birth (any gender identity);\n* HIV-positive;\n* women who have had cervical cancer precursor lesions which were removed more than 6 months ago; and\n* understand Spanish\n\nExclusion Criteria:\n\n* ages outside of the specified inclusion criteria;\n* women who are pregnant, less than 6 weeks postpartum, or in whom pregnancy cannot be excluded;\n* history of a Loop Electrosurgical Excision Procedure (LEEP) procedure in the last 6 months;\n* history of a hysterectomy;\n* previous diagnosis of gynecological cancer;\n* history of cancer of the anogenital tract; or\n* unable or unwilling to provide informed consent",true,"FEMALE","25 Years",{"count":72,"type":73},600,"ESTIMATED","INTERVENTIONAL",[76],"NA","This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic. With cervical cancer being a leading cause of cancer-related deaths in women living with HIV, and cervical cancer deaths being preventable through screening and early detection, this project seeks to identify factors associated with the successful implementation of the Screen, Triage, and Treat approach to inform future implementation and scale-up.",[79,80,81],"HIV Infections","HPV Infection","Cervical Cancer",[83,84,85,80],"People living with HIV (PLWH)","Cervical cancer screening","Spanish speakers","2026-02-24",{"date":88,"type":89},"2026-02-25","ACTUAL",{"date":91,"type":89},"2026-02-23",{"date":93,"type":73},"2029-11-01",{"name":5,"class":6},1]