[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642289":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":24,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":61,"whyStopped":24,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":24},{"fullName":5,"class":6},"Al-Zaytoonah University of Jordan","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"experimental group","EXPERIMENTAL","aerobic exercise with blood flow restriction (BFR) training Procedure: Aerobic Exercise Training Device: Blood Flow Restriction Cuff",[13],"Other: Aerobic Exercise Combined with Blood Flow Restriction",{"label":15,"type":10,"description":16,"interventionNames":17},"control group","aerobic exercise",[18],"Other: Aerobic exercise",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Aerobic Exercise Combined with Blood Flow Restriction","Aerobic exercise combined with blood flow restriction (BFR) is a rehabilitation technique in which patients perform low- to moderate-intensity aerobic exercise, such as treadmill or cycling training, while a specialized cuff is applied around the proximal part of the limb to partially restrict blood flow. This method aims to enhance muscle strength and functional performance using lower exercise intensity, making it suitable for patients with limited exercise tolerance, such as individuals with COPD.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Aerobic exercise","The control group performed conventional aerobic exercise training at low to moderate intensity without the application of blood flow restriction. The program included activities such as treadmill walking or cycling to improve cardiovascular endurance, functional capacity, and overall physical fitness in patients with COPD.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"hanan mohamed","CONTACT","+962775661825","h.hosny@zuj.edu.jo",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Hanan Hosny M Battesha","associate professor hanan hosny M Battesha","100642289","improve-muscle-weakness-in-patient-with-copd-100642289",false,"NCT07649850","Improve Muscle Weakness in Patient With COPD","Aerobic Exercise Combined With Blood Flow Restriction Improves Muscle Strength and Functional Capacity In Patients With Emphysematous COPD: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients diagnosed with emphysematous chronic obstructive pulmonary disease (COPD).\n* Clinically stable COPD patients with no acute exacerbation within the previous 4-6 weeks.\n* Mild to moderate disease severity according to GOLD criteria.\n* Ability to participate safely in aerobic exercise training.\n* Medically stable and cleared by a physician for pulmonary rehabilitation.\n* Ability to understand and follow study instructions.\n\nExclusion Criteria:\n\n* Acute COPD exacerbation or respiratory infection during the study period.\n* Severe cardiovascular diseases (e.g., unstable angina, uncontrolled hypertension, recent myocardial infarction).\n* Peripheral vascular disease or contraindications to blood flow restriction (BFR) training.\n* Severe musculoskeletal, neurological, or orthopedic disorders limiting exercise performance.\n* Cognitive impairment affecting cooperation or informed consent.\n* Participation in another structured rehabilitation program during the study period.\n* Severe hypoxemia requiring continuous oxygen therapy during exercise.\n* History of deep vein thrombosis or clotting disorders.","ALL","50 Years","70 Years",{"count":50,"type":51},60,"ESTIMATED","INTERVENTIONAL",[54],"NA","This randomized controlled trial investigated the effects of combining aerobic exercise with blood flow restriction (BFR) training in patients with emphysematous chronic obstructive pulmonary disease (COPD). The study aimed to determine whether adding BFR to aerobic exercise could enhance muscle strength and functional capacity compared with conventional training alone. The findings demonstrated that aerobic exercise combined with BFR significantly improved lower-limb muscle strength, exercise tolerance, and functional performance in patients with emphysematous COPD. These results suggest that BFR-assisted aerobic training may serve as an effective and safe rehabilitation strategy to improve physical function and quality of life in this population.",[57],"Emphysema or COPD",[59,60,16],"emphysematous COPD","lood flow restriction (BFR)","NOT_YET_RECRUITING","2026-06-11",{"date":64,"type":65},"2026-06-16","ACTUAL",{"date":67,"type":51},"2026-06-10",{"date":69,"type":51},"2026-08-30",{"name":5,"class":6}]