[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497919":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":17,"responsibleParty":33,"collaborators":36,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":7,"eligibilityCriteria":44,"healthyVolunteers":41,"sex":45,"minAge":46,"maxAge":7,"enrollmentInfo":47,"targetDuration":7,"studyType":50,"phases":7,"briefSummary":51,"conditions":52,"keywords":7,"overallStatus":20,"whyStopped":7,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"University of Aarhus","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Ina Marie Dueholm Hjorth, MD","PRINCIPAL_INVESTIGATOR",[13],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+4526192456","imhjorth@gmail.com",[18],{"facility":19,"status":20,"city":21,"state":7,"zip":7,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Department of Gynaecology and Obstetrics, Aarhus University Hospital","RECRUITING","Aarhus","Denmark","DK",{"type":25,"coordinates":26},"Point",[27,28],10.21076,56.15674,{"lat":28,"lon":27},[31],{"name":10,"role":14,"phone":32,"phoneExt":7,"email":7},"+45 26192456",{"type":11,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Ina Marie Dueholm Hjorth","Medical doctor, PhD student",[37],{"name":38,"class":6},"Aarhus University Hospital","100497919","improved-diagnosis-of-ovarian-cancer-by-use-of-circulating-tumor-dna-as-a-biomarker-100497919",false,"NCT05763511","Improved Diagnosis of Ovarian Cancer by Use of Circulating Tumor DNA as a Biomarker","Inclusion Criteria:\n\n* Suspected ovarian neoplasm\n* Informed consent\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* Previous ovarian cancer diagnosis","FEMALE","18 Years",{"count":48,"type":49},300,"ESTIMATED","OBSERVATIONAL","This project investigates circulating tumor DNA (ctDNA) in patients with suspected ovarian malignancy.\n\nWe hypothesize that measurement of ctDNA in women with suspected ovarian cancer can improve the diagnostic efficiency for preoperative differentiation between benign and malignant masses.\n\nSpecifically, we hope to determine the diagnostic efficiency of ctDNA alone and ctDNA in combination with imaging modalities (ultrasonography, MRI, PET-CT) and CA 125 for preoperative differentiation between benign and malignant adnexal masses. Based on this, we hope to develop an improved diagnostic algorithm.\n\nThe mutational profile and relation to tumour type, stage, treatment response and prognosis will be explored.\n\nAnalyses of blood and tissue samples will be used to examine the disease development and biology.\n\nBlood samples, tumour tissue and data on imaging modalities as well as CA 125 will be collected prospectively in consecutive women referred to Aarhus University Hospital.",[53,54,55],"Ovarian Neoplasms","Ovary Cancer","Ovarian Cysts","2024-05-08",{"date":58,"type":59},"2024-05-09","ACTUAL",{"date":61,"type":59},"2022-07-01",{"date":63,"type":49},"2029-05-04",{"name":5,"class":6},1]