[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576522":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":31,"centralContacts":39,"locations":45,"responsibleParty":61,"collaborators":31,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":31,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":48,"whyStopped":31,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Fondazione Don Carlo Gnocchi Onlus","OTHER",[8,14,17,23],{"label":9,"type":10,"description":11,"interventionNames":12},"CIP-FES","EXPERIMENTAL","Each subject will receive 15 individual rehabilitation sessions, each lasting 60 minutes, conducted 3 to 5 times per week over a period of 5 to 3 weeks, depending on the weekly frequency,\n\nIntentional, repetitive movements, such as lower limb movements within goal-oriented mobility tasks, will be performed, with FES applied in parallel. Two approaches will be used: (i) assistive stimulation for passive patients with poor muscle strength, and (ii) proportional active stimulation for subjects with residual muscle strength.",[13],"Other: Rehabilitation protocol: FES",{"label":15,"type":10,"description":11,"interventionNames":16},"CIM-FES",[13],{"label":18,"type":19,"description":20,"interventionNames":21},"CIP-CON","ACTIVE_COMPARATOR","Each subject will receive 15 individual rehabilitation sessions, each lasting 60 minutes, conducted 3 to 5 times per week over a period of 5 to 3 weeks, depending on the weekly frequency,\n\nIntentional, repetitive movements, such as lower limb movements within goal-oriented mobility tasks (e.g., overground straight walking), will be performed without FES. The electrical stimulator will be positioned, and the amplitude will be set to zero",[22],"Other: Rehabilitation protocol without FES",{"label":24,"type":19,"description":20,"interventionNames":25},"CIM-CON",[22],[27,32,36],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Rehabilitation protocol: FES","Subjects diagnosed with CIP will follow the FES-based rehabilitation protocol",[9],null,{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Rehabilitation protocol without FES","Subjects belonging to the control group will follow the rehabilitation protocol without FES",[24,18],{"type":6,"name":28,"description":37,"armGroupLabels":38,"otherNames":31},"Subjects diagnosed with CIM will follow the FES-based rehabilitation protocol",[15],[40],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},"Tiziana Lencioni","CONTACT","00390240308547","tlencioni@dongnocchi.it",[46],{"facility":47,"status":48,"city":49,"state":31,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"IRCCS Fondazione Don Carlo Gnocchi Onlus","RECRUITING","Milan","20148","Italy","IT",{"type":54,"coordinates":55},"Point",[56,57],12.59836,42.78235,{"lat":57,"lon":56},[60],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},{"type":62,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100576522","improved-recovery-of-walking-in-acquired-muscle-weakness-100576522",false,"NCT06786390","Improved Recovery of Walking in Acquired Muscle Weakness","Regaining Walking Ability Easier and Better in Critical Illness Polyneuropathy and Myopathy","Re-Walk-Easy","Critical Illness Patient Inclusion Criteria:\n\n* clinical diagnosis of tetra\u002Fparaparesis of peripheral origin as disclosed by ENG\u002FEMG examination;\n* be independent before the episode of critical illness\n\nCritical Illness Patient Exclusion Criteria:\n\n* history of previous comorbidity for ICU-AW;\n* previous known chronic polyneuropathy;\n* severe coagulopathy;\n* severe disorder of consciousness;\n* contraindications to Electrical Stimulation application\n\nHealthy Subjects Exclusion Criteria:\n\n* Prosthetic implants\n* musculoskeletal, neurological, cardiovascular and pulmonary disorders that may alter the gait",true,"ALL","18 Years","85 Years",{"count":76,"type":77},72,"ESTIMATED","INTERVENTIONAL",[80],"NA","The aim of Re-Walk-Easy is to evaluate the effects of rehabilitation based on electrical stimulation on the motor performance of critically ill patients. The study will also investigate the pathophysiology of the two forms-the myopathic-predominant and the polyneuropathic-predominant variants-by examining the longitudinal progression of CIP and CIM and determining which form benefits more from electrical stimulation as a rehabilitative approach.",[83,84],"Critical Illness Myopathy","Critical Illness Polyneuropathy",[86,87,88],"Functional Electrical Stimulation","Acquired Muscle Weakness","Rehabilitation","2025-02-27",{"date":91,"type":92},"2025-03-03","ACTUAL",{"date":94,"type":92},"2025-02-25",{"date":96,"type":77},"2027-12",{"name":5,"class":6},1]