[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576463":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":24,"responsibleParty":39,"collaborators":24,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":43,"sex":49,"minAge":50,"maxAge":24,"enrollmentInfo":51,"targetDuration":24,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":66,"whyStopped":24,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":24},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Gastrodia elata Blume water extract","EXPERIMENTAL","Subjects will receive Gastrodia elata Blume water extract",[13],"Dietary Supplement: Gastrodia elata Blume water extract",{"label":15,"type":16,"description":17,"interventionNames":18},"Gastrodia elata Blume water extract-like","PLACEBO_COMPARATOR","Subjects will receive a placebo resembling Gastrodia elata Blume water extract",[13],[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DIETARY_SUPPLEMENT","Subjects in the experimental group will consume Gastrodia elata Blume water extract daily. The extract is prepared from dried Gastrodia elata Blume, which is processed into a water-soluble form. This dosage is administered orally for a duration of a week. The intervention is designed to evaluate the potential effects of Gastrodia elata Blume on alleviating depressive symptoms, improving autonomic nervous system function, and enhancing overall quality of life in terminal cancer patients.",[9,15],null,[26],{"name":27,"affiliation":5,"role":28},"Jaw Shiun Tsai","STUDY_CHAIR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Yen Yu Lin","CONTACT","+886-935-812-319","hannahlin1231@gmail.com",{"name":27,"role":32,"phone":36,"phoneExt":37,"email":38},"+886-223123456","265147","jawshiun@ntu.edu.tw",{"type":40,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100576463","improvement-of-depression-in-terminal-cancer-patients-100576463",false,"NCT06785623","Improvement of Depression in Terminal Cancer Patients","Improvement of Depression in Terminal Cancer Patients (IDTCP)","IDTCP","Inclusion Criteria:\n\n* Age \\> 20 years\n* Diagnosis of terminal cancer, with an expected life expectancy of less than 6 months-\n* Patients with sufficient cognitive status to respond to the research staff's evaluation questions\n\nExclusion Criteria:\n\n* Patients or their families who refuse to participate\n* Patients who withdraw from the study\n* Patients who have participated in other research studies within one month before or during the trial\n* Patients with suicidal tendencies","ALL","20 Years",{"count":52,"type":53},60,"ESTIMATED","INTERVENTIONAL",[56],"NA","This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients. In Taiwan, cancer accounts for 25-30% of annual deaths, with terminal patients often experiencing physical pain and psychological distress, including depression. Addressing both physical and psychological challenges is vital in palliative care.\n\nGastrodia elata Blume is a traditional dietary medicine known for its antidepressant, anti-inflammatory, antioxidant, neurotransmitter-regulating, and neuroprotective properties. This trial will recruit 60 hospice patients, randomly divided into two groups: a control group and a WGE experimental group.\n\nAssessments will include:\n\n1. General examinations (e.g., height, weight, blood pressure).\n2. Non-invasive autonomic nervous system analyses.\n3. Patient-reported measures: Quality of Life Scale (EORTC QLQ-C30), Pain Score, and Hospital Anxiety and Depression Scale (HADS).\n\nThe study hypothesizes that WGE can:\n\n1. Alleviate depressive symptoms.\n2. Enhance autonomic nervous system function.\n3. Improve the quality of life for terminal cancer patients.\n\nThis research aims to demonstrate the therapeutic potential of WGE, improving psychological and physiological outcomes for hospice patients.",[59,60,61],"Depression","Cancer Patients and Depression and Suicide","Life Quality",[63,64,65],"depression","terminal cancer patients","palliative care","NOT_YET_RECRUITING","2025-01-19",{"date":69,"type":70},"2025-01-21","ACTUAL",{"date":72,"type":53},"2025-01-14",{"date":74,"type":53},"2025-12-31",{"name":5,"class":6}]