[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100427401":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":29,"locations":29,"responsibleParty":30,"collaborators":34,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":29,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":63,"whyStopped":29,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":29},{"fullName":5,"class":6},"University of Geneva, Switzerland","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"1 tDCS Parietal","EXPERIMENTAL","Anodal tDCS applied to the right inferior parietal cortex",[13],"Device: transcranial direct current stimulation (tDCS)",{"label":15,"type":10,"description":16,"interventionNames":17},"2 tDCS Frontal","Anodal tDCS applied to the medial frontal cortex",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"3 Sham","SHAM_COMPARATOR","Sham tDCS (control, no stimulation delivered). Following a standard sham protocol, in this condition the tDCS will be active the first 30seconds and the last 30seconds of the session, but silent during the other 19minutes",[13],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","transcranial direct current stimulation (tDCS)","We will apply tDCS to the patients' brains for 20 minutes at the intensity of 1.5mA. Each patient will undergo the three sessions (separated by at least 24h to minimize carry-over effects), in a pseudo-randomized order across patients.",[9,15,19],null,{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Roberta Ronchi","Dr",[35],{"name":36,"class":6},"University Hospital, Geneva","100427401","improving-awareness-for-spatial-neglect-with-tdcs-100427401",false,"NCT04845529","Improving Awareness for Spatial Neglect With tDCS","Improving Awareness in Right-brain-damaged Patients With Unilateral Spatial Neglect Using Transcranial Direct Current Stimulation (tDCS)","ANOSO","Inclusion Criteria:\n\n* First stroke affecting the right-hemisphere\n* Presence of USN, as assessed by a standard neuropsychological evaluation\n* Structural images of the brain lesion available (magnetic resonance or tomographic scans)\n* Criteria for electrical brain stimulation\n* Good (or corrected) visual acuity\n* High proficiency in French\n* Right-handed\n\nExclusion Criteria:\n\n* Presence of general cognitive deficits and\u002For suspicious of possible cognitive deficits\n* Presence of difficulty in task's comprehension\n* Impossibility to sustain a research session of at least 45minutes (e.g., attentional lability)\n* Precedent additional neurological disorder and\u002For current or precedent psychiatric disease\n* Presence of one or more exclusion criteria for the electrical brain stimulation 18, as following:\n\nPresence (or suspected presence) of metal in the brain or skull or body (except titanium) (e.g. splinters, fragments, clips, etc.) Presence of cochlear implants, implanted neuro-stimulator (e.g., DBS, epidural\u002Fsubdural, VNS), cardiac pacemaker, medication infusion device, spinal or ventricular derivations Presence of epilepsy (participant and\u002For the close family) and\u002For precedent epileptic seizures (participant) Presence of a fainting spell or syncope, due to neurological diseases (not consider syncope during blood sampling or after being in a warm environment or after emotionally stressful events) Presence of a severe (i.e., followed by loss of consciousness) head trauma Presence of hearing problems or ringing in your ears (e.g. tinnitus) Current treatment under psychoactive (e.g. antidepressants, tranquilizers) or antiepileptic medications Chronic headache For women: you are pregnant or there is any chance that you might be.","ALL","20 Years","85 Years",{"count":49,"type":50},12,"ESTIMATED","INTERVENTIONAL",[53],"NA","Brain-damaged patients can show severe neurological and cognitive deficits, and yet often remain strikingly unaware of these symptoms: this condition is called anosognosia. The aim of this study is to improve awareness in right-brain-damaged patients with Unilateral Spatial Neglect (USN) following stroke using transcranial direct current stimulation (tDCS). tDCS is a neuromodulatory technique that delivers low-intensity current to the brain facilitating (anodal tDCS) or inhibiting (cathodal tDCS) spontaneous neuronal activity. tDCS does not induce activity in resting neuronal networks, but modulates spontaneous neuronal activity: consequently, the amount and direction of effects critically depend on the previous state of the neural structures.\n\nWe will test USN patients showing anosognosia for neglect symptoms. Different brain areas will be stimulated, to target explicit and implicit components of anosognosia, including parietal and frontal brain regions.",[56,57,58],"Stroke","Anosognosia","Neglect, Hemispatial",[60,61,62],"Brain modulation","Recovery","Implicit and explicit anosognosia","NOT_YET_RECRUITING","2025-05-23",{"date":66,"type":67},"2025-05-30","ACTUAL",{"date":69,"type":50},"2026-12",{"date":71,"type":50},"2027-01",{"name":5,"class":6}]