[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637769":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":11,"locations":29,"responsibleParty":48,"collaborators":51,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":11,"enrollmentInfo":69,"targetDuration":11,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"RTI International","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CUPID shared decision-making counseling intervention","EXPERIMENTAL",null,[13],"Behavioral: CUPID shared decision-making counseling intervention",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":11},"BEHAVIORAL","The CUPID shared decision-making counseling intervention involves delivery of a paper-based, shared decision-making tool in community and clinic settings by PrEP delivery staff and Community Health Teams affiliated with each health facility. The intervention is designed as a single session in which a couple will go through the decision tool, guided by a trained member of a Community Health Team (which can include Community Health Extension Workers, Peer Educators, PrEP Ambassadors, Village Health Teams, or other personnel affiliated with MOH clinics trained to operate in communities), with onsite support, as needed, from a PrEP delivery staff, counselors, or other health providers. The CUPID shared decision-making model provides a patient-centered approach to encourage an informed and active role in decision making by providing couples with knowledge about the available options and helping to clarify their needs and values relevant to the decision.",[9],[20,24,27],{"name":21,"affiliation":22,"role":23},"Brenda Gati Mirembe, MBChB, MSc","Makerere University-Johns Hopkins Research Collaboration \u002FMU-JHU CARE LTD","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":26,"role":23},"Carolyne A Akello, MBChB, MSc","MU-JHU Research Collaboration\u002F Ministry of Health",{"name":28,"affiliation":5,"role":23},"Alexandra M Minnis, PhD, MPH",[30],{"facility":31,"status":32,"city":33,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Makerere University-Johns Hopkins University Research Collaboration MU-JHU Care","RECRUITING","Kampala","Uganda","UG",{"type":37,"coordinates":38},"Point",[39,40],32.58219,0.31628,{"lat":40,"lon":39},[43],{"name":44,"role":45,"phone":46,"phoneExt":11,"email":47},"Dr. Brenda Gati Mirembe, MBChB, MSc","CONTACT","(+256) 200 404 100","bgati@mujhu.org",{"type":23,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Alexandra Minnis","Principal Investigator; Director, Public Health",[52,55,57],{"name":53,"class":54},"National Institute of Mental Health (NIMH)","NIH",{"name":56,"class":6},"MU-JHU CARE",{"name":58,"class":6},"University of Washington","100637769","improving-choice-and-use-of-biomedical-hiv-prevention-for-women-in-uganda-a-couples-based-approach-100637769",false,"NCT07574619","Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach","CUPID","Inclusion Criteria:\n\nAll Aims:\n\n1. Able and willing to provide written informed consent\n2. Fluent in English or the dominant language spoken in the health facility's region.\n\nAim 1:\n\n1. Age ≥18 years\n2. Meets one of the following criteria:\n\n   1. Performs tasks related to PrEP outreach and\u002For delivery in former CATALYST study areas. This may include clinic and non-clinic positions.\n   2. Is a member of one of the three regional CATALYST CABs\n3. Willing to participate in a focus group discussion\n\nAim 2:\n\n1. Aged 18 years or older\n2. Attending a PrEP follow-up visit\n3. Able and willing to complete all study procedures.\n\nAim 3:\n\n1. Age ≥18 years\n2. Meets one of the following criteria:\n\n   1. CUPID couples' decision tool user\n   2. A CUPID intervention provider (member of a CHT or other PrEP Provider)\n   3. A provider offering PrEP choice through a health facility where CUPID is implemented\n   4. MOH or District Health Official\n3. Willing to complete a questionnaire and participate in a qualitative interview (individual or dyadic)\n\nExclusion Criteria:\n\nAll Aims: Participants will be excluded who have any condition that, in the opinion of the MPI or designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.\n\nAim 2:\n\nExclusion criteria: Participants aged 15-17 years",true,"ALL","18 Years",{"count":70,"type":71},1424,"ESTIMATED","INTERVENTIONAL",[74],"NA","This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics already providing choices for PrEP in Uganda, the investigators will evaluate whether CUPID is effective in increasing PrEP uptake, persistence, and use among Ugandan women and assess implementation outcomes to determine whether it is acceptable and feasible to implement. If successful, CUPID will offer a community-based strategy for engaging male partners to support PrEP choice and improve HIV prevention among women and provide a scalable and sustainable intervention that will contribute to a more comprehensive approach to HIV prevention.",[77],"HIV",[79,80,81,82,34,83,84,85],"CAB-PrEP","LEN-PrEP","Oral PrEP","PrEP Ring","Couples","Decision Tool","PrEP Choice","2026-05-14",{"date":88,"type":89},"2026-05-18","ACTUAL",{"date":91,"type":89},"2026-05-13",{"date":93,"type":71},"2028-03",{"name":5,"class":6},1]